Follica

[Kalio]

How will this work? Will Follica be some kind of injectable or rather just a topical? If its applied per injection, will it be mandatory to repeat the treatment every year or so?

[DepressedByHairLoss]

Well, it will happen some day. It better happen within a few years. I'll be right pissed if it doesn't. However, when and how is pure speculation, but since we're putting our hopes on Follica, it may be within a few years and we have a general idea of how it will be administered due to the publicly released patents.

The risk of them losing money now is near zero... but thats IF the hair that they claimed to be able to create with neogenesis is actually terminal hair. Spencer Kobren and Joe From Staten Island both commented and confirmed that Follica did successfully grow new hair from neogenesis in human clinical trials and are now in Phase IIb trials. But thats as much info as we know. So if its terminal hair... we can basically say 'case closed' and wait until Follica is given the green light and put snake oil salesman out of business and bury them into such a deep hole they'll never know the meaning of light... as they should.

But, I think they do have the cure. Why? Well, we saw from the barbecue head guy grew terminal hair after wounding, laser tattoo removal grew new hair, the hairy hand case and the kid with his arm that grew hair all over. All of the cases exhibited terminal hairs. So, Follica is perfecting this method and I'm fairly certain they've got it figured out.

I'm still hoping/pushing that we try to get around their procedure ourselves somehow... still believe injections or some kind of application of FGF-9 after wounding may get us there. So far, noone has been brave enough to try it. FGF-9 is available at 5mcg for $50.

Hellouser, I am interested in that 3rd paragraph where you talk about these people regrowing hair. Can you maybe provide some links? I'd love to read up on them.

[hellouser]

How will this work? Will Follica be some kind of injectable or rather just a topical? If its applied per injection, will it be mandatory to repeat the treatment every year or so?

Basically:

1) Strip (wound) layer of skin on scalp
2) Slow down healing
3) Apply topicals
4) Get laid with hair

I actually had an appointment this morning with my dentist. A checkup actually in regards to the gum grafting I had done a couple months ago. He mentioned he'll need to smoothen out the excess gum tissue in a couple months with a laser. This is where it gets interesting;

Basically the laser is like a pen and vaporizes the tissue. I asked him if it could be used on skin, suppose for a tattoo removal (didn't want to mention hair loss). He said the laser pen vaporizes tissue sometimes potentially up to 3mm deep. I couldn't understand him when he said the name of the laser, but this is a good start for those of us (hopefully all of us) interested in replicating Follica's wounding method.

I need to get my hands on this laser!

[hellouser]

Two lasers I found:

http://www.biolase.com/products/ezlase/features.html

http://www.biolase.com/products/ilase/features.html

Hmmmm!

[Kalio]

Basically:

1) Strip (wound) layer of skin on scalp
2) Slow down healing
3) Apply topicals
4) Get laid with hair

Very interesting, how often do you reckon one should repeat these steps in order to get a full head of hair?

Also, how do you slow down healing? Is that by using one of those dermarollers on the same wound before it is fully healed?

[UK_]

Basically:

1) Strip (wound) layer of skin on scalp
2) Slow down healing
3) Apply topicals
4) Get laid with hair

I actually had an appointment this morning with my dentist. A checkup actually in regards to the gum grafting I had done a couple months ago. He mentioned he'll need to smoothen out the excess gum tissue in a couple months with a laser. This is where it gets interesting;

Basically the laser is like a pen and vaporizes the tissue. I asked him if it could be used on skin, suppose for a tattoo removal (didn't want to mention hair loss). He said the laser pen vaporizes tissue sometimes potentially up to 3mm deep. I couldn't understand him when he said the name of the laser, but this is a good start for those of us (hopefully all of us) interested in replicating Follica's wounding method.

I need to get my hands on this laser!

Hahahaha Hellouser man I love how you always wanna figure this shit out on your own - that's what we need, not sitting on our hands waiting for something to fall into our laps.

[Pentarou]

Two lasers I found:

http://www.biolase.com/products/ezlase/features.html

http://www.biolase.com/products/ilase/features.html

Hmmmm!

This is definitely an avenue of research worth investigating IMO.

[UK_]

If Nigam is actually doubling then I will go for a procedure 100% and its looking more promising by the day.

Maybe we could ask Nigam to look into the Follica method to see if he is able to understand/investigate what they're doing to grow hair.

[hellouser]

Very interesting, how often do you reckon one should repeat these steps in order to get a full head of hair?

Getting laid wont regrow hair unfortunately, but that in itself is better than hair. I think the steps may need to be repeated until you're happy with the results. However, thats pure speculation as I'm unsure how the topicals applied will affect hair growth (how much of them used will probably play a role)

Also, how do you slow down healing? Is that by using one of those dermarollers on the same wound before it is fully healed?

Not completely sure, as I don't remember, but it may Lithium Gluconate that slows down the healing, but it needs to be a substantial wound too. I've got a feeling that we'll probably be left with scabs after on our scalp. Again, pure speculation.

[Pentarou]

Spencer and Joe From Staten Island both stated they are in human clinical trials and both said that Follica succesfully grew hair through NEOGENESIS.

Puretech Ventures which is funding Follica, clearly states on their website they are in Human Clinical Trials:

http://www.puretechventures.com/pipeline.php

From what I've read/heard, Follica doesn't need a complete 3 phase trials as the substances theyre using to generate new follicles are 'known substances' and apparently they only need approval for the wounding device (which, what we know from the released patents is a laser). If anyone has more concrete info, please correct me on any of the points i've made, im not 100% sure, theres too much info coming through the pipes lately with all the hair loss solutions (which, is a good thing, finally)

Following the recent Garza interview, I really think that one of us really needs to get in contact with PureTech to find out if Follica actually are undergoing trials (a simple yes or no answer would suffice I guess).

[garethbale]

Following the recent Garza interview, I really think that one of us really needs to get in contact with PureTech to find out if Follica actually are undergoing trials (a simple yes or no answer would suffice I guess).

Yeah I was thinking that earlier.

Will email them this weekend. They will probably disclose nothing but I will ask anyway

[Artha]

There a new patent that just been publish 2 days ago!

http://patentscope.wipo.int/search/en/WO2013142295

http://patentscope.wipo.int/search/en/detail.jsf?docId=WO2013142295&recNum=1&maxRec=&office=&prevFilter=&sortOption=&queryString=&tab=PCTDescription

[walrus]

There a new patent that just been publish 2 days ago!

http://patentscope.wipo.int/search/en/WO2013142295

http://patentscope.wipo.int/search/e...PCTDescription

Nice find! Includes some info on DP-2 antagonist clinical trials that could be used.

[Thinning87]

Notice the very last paragraph

[Artha]

Notice the very last paragraph

[00123] It will be appreciated by those skilled in the art that changes could be made to the embodiments described above without departing from the broad inventive concept thereof. It is understood, therefore, that this invention is not limited to the particular embodiments disclosed, but it is intended to cover modifications that are within the spirit and scope of the invention, as defined by the appended claims.

That?

A little more about Dr. Cotsarelis

Dr. Cotsarelis is a consultant for Proctor and Gamble, Stiefel/GSK and Follica, has stock options from Follica and received
a sponsored research agreement from L’Oreal.