custom growth factors

[lilpauly]

Something tells me the growth factors with VIGOROUS wounding (2-3mm dermaroller) may give Histogen like results.

It could be a game changer , I am asking every 1 who is using the growth factors to keep every1 updated

[Arashi]

Its not very accurate.

Actually I'm always amazed at how good it is. Of course it's not perfect especially not if users make typo's (like unfortunately quite a few of the users in that thread do), but it's good enough to see what they're talking about and that there's no interesting info there just yet (Wesley just received his growthfactors). Hopefully soon to come.

[hellouser]

Never heard about google translate ?
http://translate.google.nl/translate...D32621&act=url

Its not very accurate.

[Arashi]

How many people on this forum can understand or speak Dutch? Thread link useless.

Never heard about google translate ?

http://translate.google.nl/translate?sl=nl&tl=en&js=n&prev=_t&hl=nl&ie=UTF-8&u=http%3A%2F%2Fwww.haarweb.nl%2Fforum%2Fshowthread.php%3Ft%3D32621&act=url

[hellouser]

There is approx 12 of us and none have gotten the grow th factors yet , boldy might get them tommorow , u can google translate it or I will post it english

Something tells me the growth factors with VIGOROUS wounding (2-3mm dermaroller) may give Histogen like results.

[lilpauly]

How many people on this forum can understand or speak Dutch? Thread link useless.

Lilpauly, are they experiencing results? What's the feedback like?

There is approx 12 of us and none have gotten the grow th factors yet , boldy might get them tommorow , u can google translate it or I will post it english

[StayThick]

http://www.haarweb.nl/forum/showthread.php?t=32621

How many people on this forum can understand or speak Dutch? Thread link useless.

Lilpauly, are they experiencing results? What's the feedback like?

[Arashi]

Some1 is using the growth factors in the Dutch forum I will post the thread

http://www.haarweb.nl/forum/showthread.php?t=32621

[lilpauly]

Some1 is using the growth factors in the Dutch forum I will post the thread

[StayThick]

there are some who strongly disagree with this statement hell. i think one was stoic at *******. he thinks wounding every few days is better but of course now i've forgotten his reasoning, but at the time it made sense.

It's all experimental at this point, regardless of the study.

I do it 2 times a week because I heal fairly quickly, and I think I could benefit more from that extra day. I have no scientific proof that proves that though. That's just my personal choice. I don't think dermarolling 2-3 times a week will have less than an impact vs just doing it 1 time a week. Logic doesn't make any sense to me on how that can be.

[lilpauly]

2 or 3 times week it needs to be applied.

[hellouser]

there are some who strongly disagree with this statement hell. i think one was stoic at *******. he thinks wounding every few days is better but of course now i've forgotten his reasoning, but at the time it made sense.

Here's what I'm basing it off (mind you, I'm not saying wounding more than once a week will give worse or better results, none of us are sure yet)

These results imply a regulatory network in hair follicles wherein PGD2 inhibits, whereas PGE2/F2a promote, hair follicle function.
PGs are key inflammatory mediators involved in wound. We also found that during wound healing, the capacity of tissue to generate PGE2 and PGD2 is separated over time, thus providing evidence consistent with the distinct functions of PGs. These results are similar to those observed after incisional wound healing in DBA/I mice (Kapoor et al., 2007). In C57Bl/ 6J and DBA/I strains and models of wound healing, PGE2 is the more abundant product during the early phases of wound healing. Elevated levels of PGE2, a potent immune activator, are consistent with progressing inflammation (Sakata et al., 2010). Whereas, at later stages, when inflammation is resolving, PGE2 levels taper off and PGD2 becomes the predominant PG.

Read more here: http://www.baldtruthtalk.com/showpos...&postcount=547

[Conpecia]

I would stick to wounding once a week, I posted in my dermaroller thread that the healing process is typically over after about 10 days, so dermarolling more than once a week may not allow for all the growth factors to be induced ON TIME, which Follica even suggests that timing is a factor.

there are some who strongly disagree with this statement hell. i think one was stoic at *******. he thinks wounding every few days is better but of course now i've forgotten his reasoning, but at the time it made sense.

[hellouser]

Yeah i will, but i dont know if wounding with a 1.5mm and the next day after dermarolling with a 0.5mm wont interfere with the healing process etc, have to read about that. I know 0.5mm is enough for those growth factors to reach up past the skin and exert a biological activity. I do agree that wounding could have a synergistic effect with growth factors + minoxidil (b catenin expression, vccg turn off >fstl1 >bmp4 antagonist, pge2 inducer, damn minox is great lol!) + will be using RU too. So my regimen will be RU + growth factors + minoxidil+ wounding.

I want to get better results as the study, and thats why i will be using it 2-3 times a week 2 times a day. I'm not worried myself about cancer risk or other side-effects, as this seems to be a pretty balanced growth factor mixture. Plus the dosage is pretty safe too imo, just look at that regranex gel with a PDGF concentration of 100ug/ml. Passed the fda though it has a risk warning, we are talking about a single exogenous growth factor directly applied to a wound on a mega dosage. This is a way loser dose + more balanced.

Be very, VERY careful with dermarolling and RU. The easy penetration could lead RU to go systemic which may (or may not) give you bad side effects. This is why CB should be a far better option; it binds to the recept and blocks DHT at the follicle, goes benign if enters the blood stream and does not inhibit product of DHT.

I would stick to wounding once a week, I posted in my dermaroller thread that the healing process is typically over after about 10 days, so dermarolling more than once a week may not allow for all the growth factors to be induced ON TIME, which Follica even suggests that timing is a factor.

[Imalmostbald]

lilpauly mentioned once a week application should suffice. Also, if youre going to go down the experimental route, I would recommend to try deep dermarolling/wounding FIRST and then applying the growth factors as the penetration through skin will be MUCH easier and perhaps (and most likely) a synergistic effect between wounding/healing/growth factors.

Yeah i will, but i dont know if wounding with a 1.5mm and the next day after dermarolling with a 0.5mm wont interfere with the healing process etc, have to read about that. I know 0.5mm is enough for those growth factors to reach up past the skin and exert a biological activity. I do agree that wounding could have a synergistic effect with growth factors + minoxidil (b catenin expression, vccg turn off >fstl1 >bmp4 antagonist, pge2 inducer, damn minox is great lol!) + will be using RU too. So my regimen will be RU + growth factors + minoxidil+ wounding.

I want to get better results as the study, and thats why i will be using it 2-3 times a week 2 times a day. I'm not worried myself about cancer risk or other side-effects, as this seems to be a pretty balanced growth factor mixture. Plus the dosage is pretty safe too imo, just look at that regranex gel with a PDGF concentration of 100ug/ml. Passed the fda though it has a risk warning, we are talking about a single exogenous growth factor directly applied to a wound on a mega dosage. This is a way loser dose + more balanced.