ragsta what mm roller are you using?
Dermarolling Community Trial
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35 years,
Since you work in a HT clinic, would you be able to inquire as to any risks of long term damage by eitiher normal microneedling or excessive microneedling. Is there a chance that we could be scarring, or if not scarring our skin, making it thicker such that it would harm results of a future transplant in the recepient area?Comment
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Someone claiming they've bad permanent scarring from a derma roller session
"I have had two dermaroller treatments and the second one effectively ruined my life.";
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Looking over this thread it seems valid concerns are
1. Pushing too hard and
2. Bacterial issues surrounding improper sterilization and storing or rollers
How are you all sterilizing, and storing your dermarollers?Comment
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Looking over this thread it seems valid concerns are
1. Pushing too hard and
2. Bacterial issues surrounding improper sterilization and storing or rollers
How are you all sterilizing, and storing your dermarollers?Comment
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Im just using Isopropyl Rubbing Alcohol..hopefully thats enough.Comment
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2. Betadine, Isopropanol, Isopropyl should all be used to clean the roller. Some are boiling it hot water followed by the high concentration alcohols.
I store mine in a plastic enclose it came with and then inside the plastic tube container.Comment
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to clean it i pour betadine into a shot glass and let the roller sit in it for a few mins, I would think that would clean it pretty well...Comment
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I do this, but with TCP (it's an antiseptic), would've thought that's enough. Plus I do it just after I've had a shower so my scalp is clean.Comment
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I will ask Dr. Cole when he returns. I doesn't hurt to see what the naysayers have to report. In the case of micro needling, I see a risk of infection but that's about it:
Risk of Infection
Can you damage your skin?
I'm not a doctor and my opinions here are not to be interpreted as medical advice.
35YrsAfter also posts as CITNews and works at Dr. Cole's officeLast edited by 35YrsAfter; 02-22-2015, 03:57 PM.Comment
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no ones tried doxycycline to increase fgf9 ? seems to have already been bought up in the forum though
"To test whether increased expression of Fgf9 in the wound promotes WIHN, we overexpressed Fgf9 in the epidermis of FVB-Tg(KRT14-rtTA)F42Efu/J; TRE-Fgf9-IRES-EGFP (K14rtTA; Fgf9) transgenic mice. Administration of doxycycline to these mice induces expression of Fgf9 targeted to the epidermis by the promoter for the gene encoding keratin-14. Fgf9 expression increased 150-fold in these mice after doxycycline administration (Fig. 1d), and this led to a marked increase in the number of neogenic hair follicles compared to controls (Fig. 1e,f). These combined results indicate that modulation of Fgf9 expression in the wound affects WIHN."Comment
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Thank you 35years. Maybe you can help me with one more query?
Everyone;Comment
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VD3 pretreatment?
Rationale is based on excerpt from from highly publicized and heavily discussed study: 1α,25-dihydroxyvitamin D3 modulates the hair-inductive capacity of dermal papilla cells: therapeutic potential for hair regeneration.
"upregulation of Wnt10b, ALPL, and TGF-β2 was mediated through the genomic VDR pathway. In a rat model of de novo hair regeneration by murine DPC transplantation, pretreatment with VD(3) significantly enhanced hair folliculogenesis. Specifically, a greater number of outgrowing hair shafts and higher maturation of regenerated follicles were observed"
-Therefore as derma rolling is supposed to stimulate hair follicle neogenesis through WNT/FGF9 pathways and according to above, VD3 enhances follulogenesus (maturation) perhaps more rapid and profound results could be observed by treating scalp with VD3 prior to rolling.
Any thoughts?Comment
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Rationale is based on excerpt from from highly publicized and heavily discussed study: 1α,25-dihydroxyvitamin D3 modulates the hair-inductive capacity of dermal papilla cells: therapeutic potential for hair regeneration.
"upregulation of Wnt10b, ALPL, and TGF-β2 was mediated through the genomic VDR pathway. In a rat model of de novo hair regeneration by murine DPC transplantation, pretreatment with VD(3) significantly enhanced hair folliculogenesis. Specifically, a greater number of outgrowing hair shafts and higher maturation of regenerated follicles were observed"
-Therefore as derma rolling is supposed to stimulate hair follicle neogenesis through WNT/FGF9 pathways and according to above, VD3 enhances follulogenesus (maturation) perhaps more rapid and profound results could be observed by treating scalp with VD3 prior to rolling.
Any thoughts?Comment
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