-
-
This make a lot of sence as the needles are not rotating through the skin to enter and exit. The big question is, do you need maximum disruption to the skin OR would a simple stabbing action; in and out suffice?Sometimes the pain would be pretty bad, and I would tear up and want to sneeze, but most of the pain was coming from the actual rolling across the scalp while pressing down. Instead, I simply pressed down, moved the roller, pressed down again... repeat. Eventually you'll pierce through the skin. I'm not sure how this well translate into disrupted skin/follicles but for a final touch if you can't handle any more pain, its not a bad idea.
What about numbing the area with Ice before rolling?Comment
-
Guys, I started using my Nanogen Titanium Scalp Roller 0.5mm because the seller doesnt accept refunds. All what I can say is that it hurts and irritates sometimes. I dont think I could handle 1.5mm for God sake. Hellouser, you are really brave. I will just keep using it everyday as instructed in the leaflet. Maybe it will do something, better than nothing. Actually they mentioned in their website that
The Scalproller has 4 innovative modes of action to enhance any hair treatment regimen:
1. Increases Topical Treatment Absorption
Scalproller pre-treatment has been shown to increase absorption of topical treatments by 5 times or more. With Scalproller pre-treatment, lower 2% concentrations of a topical treatment solution will give concentrations in the scalp higher than when using 5% solutions on untreated skin. Similarly, 5% solutions will produce higher concentrations in the scalp than 12.5% solutions or suspensions used on untreated skin. Frontal scalp areas are notoriously difficult to treat topically, most probably due to lack of absorption. Therefore topical treatments are only really effective in treating vertex hair loss. Using Nanogen's Scalproller can dramatically increase absorption of topical treatments in these regions, opening up new potential areas for topical treatments to act on.
2. Heals Donor Scars
Hair transplant surgery commonly leaves scars in the donor region; Nanogen's Scalproller has been proven to fade and reduce the appearance of these scars by breaking up scar tissue structures and formations. Plus there is evidence in animal models to show that new hair may grow to conceal the donor area after Scalproller treatment.
3. Activates PRP Treatment
Platelet Rich Plasma or PRP therapy is a cutting edge development in hair loss treatment. PRP has been shown to produce thicker transplanted hair growth, and possibly even thicken non-transplanted hair. In PRP therapy, the platelet and growth factor rich fraction of the patient's blood is re-injected into them, and then growth is activated by repeated needle insertion. Single needle insertion is irregular, time consuming and often painful. Scalproller treatment produces much more reliable, regular needle insertions in less time, and with less pain.
4. Encourages New Hair Growth
The latest research by Intercytex, performed with Dr. Bessam Farjo as principal investigator, has shown that patients receiving superficial injections and controlled wounding grow new hair, which may solely be a result of the controlled skin wounding itself. This surprising result is correlated by the pioneering work published by Dr. George Cotsarelis of Pennsylvania University, who found that stimulation of the Wnt protein by wounding leads to hair regeneration. Wounding by microneedles would potentially start this Wnt protein mediated growth stimulation, and prevent synthesis of TGF-β2, a protein known to induce hair loss.
Scalproller treatment increases topical treatment penetration and may independently promote new hair growth.
Here is the Q & A
What is a Scalproller?
Nanogen's Scalproller is a treatment previously only available through Trichologists or Dermatologists. The 0.3mm & 0.5mm models have now made this treatment available for use at home. It is a cylindrical barrel with precision engineered titanium microneedles which penetrate the top layers of skin without causing damage or bleeding. This accurate and non-intrusive penetration allows much higher absorption of scalp treatments like Serum VEGF. It may also stimulate scalp healing and hair growth by itself as it can stimulate the scalp's healing response.
How will Nanogen's Scalproller Work?
As you roll the roller over your scalp it penetrates the upper layers of skin. By opening the skin in this way you dramatically increase the penetration of any topical growth product, increasing its efficacy. These perforations also stimulate the scalp's healing mechanisms, increasing production of many important factors for a healthy scalp.
Can I use the Scalproller more than once a day?
At first, the Scalproller is designed to be used once daily, and is far more intensive than any skin roller, using more than once daily may be possible after time, depending on the individual. If used more than once a day initially the Scalproller may cause more irritation than is aimed for, and even cause damage.
When using the Scalproller do I roll over each part of my scalp only once?
At first, use a single motion once over each area of scalp, rolling gently forward from the crown. This produces a controlled amount of irritation and avoids tangling the roller in longer hair. After time, individual users may prefer to roll in multiple directions.
Which needle length Scalproller should I use?
Nanogen's genuine Scalproller is available in 2 versions for home use. The 0.3mm version is recommended for patients with very thin hair or pain sensitive skin. A 0.5mm home version is available to ensure penetration even with thicker hair.
Will the Scalproller mark my scalp, cause redness, or cause pain or bleeding?
When used as directed, the Scalproller will only cause small or no marks, and the marks will fade in under a minute. Scalproller treatment may cause a flush to your scalp that will fade in a few hours, but no long-lasting redness. The Scalprollers made available for home use have sharp, durable titanium needles that do not cause appreciable pain or bleeding.
Do I use Nanogen's Scalproller over my whole scalp, or just the thinning area?
As the main aim of the Scalproller is to help topical hair loss treatments penetrate, you should use the Scalproller everywhere that you will apply your topical treatment. However using it elsewhere will certainly not do any harm.
Is this the same as other Skin or Derma Rollers?
No. Other skin rollers have different needle lengths, and are designed to be used for different purposes. Some claim they will work on Hair Loss, but Nanogen's Scalproller is the first specially designed for use on the scalp and for use every day. No other skin roller is made from unique titanium needles, so only the Scalproller can be reused intensively for 3-6 months.
Can I use a topical solution with the Scalproller?
Yes, the Scalproller is designed to be used with topical treatments to increase their efficacy, you should still follow the guidelines on your topical treatments for their application.
When do I use a topical solution with the Scalproller?
You use the Scalproller first, to increase the penetration of the treatment, then the topical treatment. You should still follow the guidelines on your topical treatments for their application.
I use more than one topical solution, which should I apply first?
The same as you did before you used the Scalproller, you should still follow the guidelines on your topical treatments for their application.
How long will the Scalproller last for?
Even when used daily, due to its unique durable titanium microneedles Nanogen's Scalproller can last from 3-6 months.
How do I know when to replace my Scalproller?
There will be no visible signs of the sharpness deteriorating. After 3 months, if you begin to notice any increase in pain or inflammation while using the Scalproller, this is a sign the needles are becoming less sharp, and you need to replace it. After 6 months you should replace your Scalproller, even if you have not noticed a difference in pain or inflammation.
Is Nanogen's Scalproller Guaranteed to Work?
Like all Nanogen products, the Scalproller is manufactured and quality controlled to exacting standards. Unfortunately, due to regulations on handling of biological material, we cannot accept returns of a used Scalproller and so cannot refund the product.
Here is the link:-
Comment
-
this has been around awhile. Dont you think somebody would have reported results (not neccessarily a forum member).
Also, if laser tattoo removal caused hair growth, dont you think somebody would have tried an experiment with it?
if not, experiments for both could easily be crowdfunded cheap.Comment
-
I've been dermarolling on and off since last November and have noticed a degree of regrowth. I just put it down to enhanced absorption of topicals, not to wounding. I wasn't aware of the wounding concept.
Not necessarily. It's taken this long to even get a study published on microneedling, even though the wounding concept has seemingly been around for years. Unfortunately we all know how slowly things seem to move in the world of hairloss treatments.Comment
-
As hellouser showed us, somebody already tried and experimented with laser:
Comment
-
1.early result week first hair is growing faster
an interesting point to expect from the study
Comment
-
I found that post very interesting because I have been using LLLT since November of 2007 myself.
I will not be changing my current regimen. I will only be adding dermarolling to my current regimen to see if doing so can improve upon what is already working for me. My regimen would not be applicable to you guys but for the ladies, here is my current regimen:
Spironolactone taken orally twice a day.
Minoxidil twice a day (foam in the AM, generic liquid in the PM).
Laser comb every other day.
Nizoral once a week.
My regular shampoo/conditioner is Aveeno "Pure Renewal" sulfate free shampoo and conditioner.
My vitamins are Nature's Bounty extra strength "Hair, Skin & Nails" multi-vitamin and vitamin D3. Both taken twice a day with meals.
I will be using the dermaroller once a week on Sunday nights. I will be prepping the area prior to dermarolling with Betadine and applying a very thin layer of Neosporin on the area afterwards. I will not be using Minoxidil on Sunday night and Monday morning. I will resume using Minoxidil on Monday evening.Comment
-
Oh, man, law school flashback... Hawkins is a hugely famous case that's taught as part of every tort curriculum. We always called it the "hairy hand case."These articles really need to be looked at by the community here. Also, and courtesy of Conpecia, he was able to remember a case from law school:
The increasing evidence of wounding theory is starting to pile up....!!! Thanks for the article ConpeciaComment
-
What do you guys and girls think of this idea. I have started a mind map for Diy wounding for hair growth on mind42.com. This is a mind map we can all edit to try and organise our ideas and resources. To edit the mind map you need me to add your email you signed up to mind42.com with to the specific mind map we are working on.
We could use this to keep track of wounding devices, links to science papers, specfic compounds that might work as growth promoters, where we might find this?
Its just an idea and there may be a better way of arranging the data we find but we def need something better than a massive thread on a single forum.
Comment
-
COOL!!
Now if only my message to Winston about unlocking private messaging was actually taken seriously, we could exchange emails privately. Eventhough I did mention integrity in regards to allowing the community come together an WORK together, this forum, despite its potential, is GIMPED.
See if you can private message me on Hair Loss Talk, my username there is also 'hellouser'
Thanks!
Comment
-
Found another article:
Wound healing
Understanding the role of stem cells in wound healingWounds develop when the epidermal layer of skin is breached by injury or infection and the severity increases when the underlying layers of skin become involved. Three steps need to occur for wounds to heal normally: inflammation, proliferation and remodeling. Inflammation lasts approximately four days. In that time the key events that happen are the generation of a fibrin matrix and the formation of a blood clot to cover and protect the wound. Immune cells, such as macrophages, also migrate into the area to clean up any cellular debris and to help prevent infections from taking hold. During the proliferation phase, inflammatory signals recruit many different cell types to the wound, including fibroblasts and vascular endothelial cells. Fibroblasts make collagen and can also turn into myofibroblasts that close the wound, and vascular endothelial cells form new blood vessels around the wound. All this cellular activity makes what is called a ‘granulation tissue’ that is located just below the blood clot. Keratinocytes then migrate to the wound from the wound edges and also from the base of hair follicles. The dividing keratinocytes move over the granulation tissue to knit the epidermis together. This process continues during the remodeling phase and once the epidermis is restored, keratinocytes and fibroblasts lay down the matrix proteins for the new basement membrane that regenerates the interface between the epidermis and the underlying dermis.
Stem cells are known to play an important role during the normal course of events that distinguish skin regeneration and wound healing. The skin is home to many different types of stem cells, including epidermal stem cells, melanocyte stem cells (which make pigment-producing cells), and epithelial and mesenchymal stem cells that reside in hair follicles. Together, these stem cells are responsible for making the multitude of different skin cells that are important for perpetually renewing normal, healthy skin. In response to general injuries the number of circulating stem cells in the body increase. Hair follicle stem cells and epithelial stem cells are thought to interact with bone marrow stem cells, which are recruited to a wound during the inflammatory phase of wound healing, and together these stem cells bring about speedy wound closure and tissue repair. As yet, it is not clear whether stem cells from the bone marrow might also contribute to the healing process by actually making new skin cells.The parts in bold are intriguing.Freda Miller at the Hospital for Sick Children in Toronto is well known for having discovered skin-derived precursors (SKPs). These are adult dermal stem cells that not only repair wounded skin but also prevent skin from aging and promote hair growth. She and her team are actively searching out drugs, small molecules and genes that can ramp up the activity of SKPs. The idea being that if they can increase the number of SKPs, they might be able to enhance skin repair and maintenance, especially as abnormal wound healing and premature aging have been linked with low levels of SKPs.
Source: http://www.stemcellnetwork.ca/index....healing&hl=eng
I might actually try and reach out to Freda Miller as she's in Toronto. Here's some of her research in regards to hair follicles: http://www.ncbi.nlm.nih.gov/pubmed/19951689Comment
-
Some other worthwhile studies to read:
Dr. Jahoda's paper on 'Changes in hair growth characteristics following the wounding of vibrissa follicles in the hooded rat' From 1984
Source: http://dev.biologists.org/content/83/1/81.full.pdf
Wnt-dependent de novo hair follicle regeneration in adult mouse skin after wounding
Source: http://www.scopus.com/record/display...8cE7qwvy6w%3a2
Specific MicroRNAs Are Preferentially Expressed by Skin Stem Cells To Balance Self-Renewal and Early Lineage Commitment
Source: http://www.sciencedirect.com/science...34590911000154Comment
-
Has anyone seen any results yet? im on 3 weeks and nothing so far. I guess it takes 6 weeks ?Comment
Tweet
Comment