Dermarolling Community Trial

[Pentarou]

I think dermarolling is an excellent idea, however, I feel it will not go far enough. Wounding grows hair, we know that, it doesn't grow enough hair to be cosmetically significant, the question is really of finding the topical compounds that are going to tickle the right chemical pathways....

I agree with the general sentiment. There's definitely potential in rolling, but we need a as-yet unknown special ingredient to kick it into growth overdrive.

[fred970]

There is plenty of evidence. Lots of forum posters say they get weird wrinkles now. Did you even read those articles?

Oh excuse me! Random people on the internet say they got wrinkles from minoxidil and that counts as evidence to you?

All people who say this read about minoxidil giving wrinkles before saying it, they started to see things. Good illustration of the placebo effect.

[Ted]

I have to agree with fred on this one. It is really hard to find before and after pictures of people getting wrinkles from minox, and in the hair loss world we all know what that means.

[fred970]

I have to agree with fred on this one. It is really hard to find before and after pictures of people getting wrinkles from minox, and in the hair loss world we all know what that means.

Thank you! As saying goes: "pictures or it never happened", we have countless before/after pictures with FDA approved treatments but not even one on the entire internet showing wrinkles from minoxidil. So the bottom line is: this never happened to anyone.

[35YrsAfter]

Thank you! As saying goes: "pictures or it never happened", we have countless before/after pictures with FDA approved treatments but not even one on the entire internet showing wrinkles from minoxidil. So the bottom line is: this never happened to anyone.

Wrinkles from using minoxidil is a bunch of BS.

35YrsAfter also posts as CITNews and works at Dr. Cole's office - forhair.com - Cole Hair Transplant, 1045 Powers Place, Alpharetta, Georgia 30009 - Phone 678-566-1011 - email 35YrsAfter at chuck@forhair.com
The contents of my posts are my opinions and not medical advice
Please feel free to call or email me with any questions. Ask for Chuck

[lilpauly]

no man its a known side effect.

Wrinkles from using minoxidil is a bunch of BS.

35YrsAfter also posts as CITNews and works at Dr. Cole's office - forhair.com - Cole Hair Transplant, 1045 Powers Place, Alpharetta, Georgia 30009 - Phone 678-566-1011 - email 35YrsAfter at chuck@forhair.com
The contents of my posts are my opinions and not medical advice
Please feel free to call or email me with any questions. Ask for Chuck

[blondetooth]

Oh excuse me! Random people on the internet say they got wrinkles from minoxidil and that counts as evidence to you?

All people who say this read about minoxidil giving wrinkles before saying it, they started to see things. Good illustration of the placebo effect.

There are pictures actually. Before and after photos a few months apart. People have documented proof of it that is clearly visible. Also hundreds of complaints and comments about it. Do a Google search and you will see I'm right. Your blind arrogance is sad.

Also there is a graph around here showing minoxidil only produces temporary results and then it useless. I would never use it, use fin for stability.

My dad was hospitalized and has permanent heart problem's from minoxidil. They were a few weeks after his first application. Not fun.

Use a dermaroller but stay away from temporary cover up chemicals that screw up your head.

[Ted]

There are pictures actually. Before and after photos a few months apart. People have documented proof of it that is clearly visible. Also hundreds of complaints and comments about it. Do a Google search and you will see I'm right. Your blind arrogance is sad.

Also there is a graph around here showing minoxidil only produces temporary results and then it useless. I would never use it, use fin for stability.

My dad was hospitalized and has permanent heart problem's from minoxidil. They were a few weeks after his first application. Not fun.

Use a dermaroller but stay away from temporary cover up chemicals that screw up your head.

Can you please link us to these pictures? I have googled but couldn't find any. I found this though http://www.realself.com/question/minoxidil-wrinkles

I also found this:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039155/

Minoxidil may suppress androgen receptor-related functions
Cheng-Lung Hsu,1 Jai-Shin Liu,1,3 An-Chi Lin,1 Chih-Hsun Yang,2 Wen-Hung Chung,2 and Wen-Guey Wu3
Author information ? Article notes ? Copyright and License information ?
Go to:
Abstract
Although minoxidil has been used for more than two decades to treat androgenetic alopecia (AGA), an androgen-androgen receptor (AR) pathway-dominant disease, its precise mechanism of action remains elusive. We hypothesized that minoxidil may influence the AR or its downstream signaling. These tests revealed that minoxidil suppressed AR-related functions, decreasing AR transcriptional activity in reporter assays, reducing expression of AR targets at the protein level, and suppressing AR-positive LNCaP cell growth. Dissecting the underlying mechanisms, we found that minoxidil interfered with AR-peptide, AR-coregulator, and AR N/C-terminal interactions, as well as AR protein stability. Furthermore, a crystallographic analysis using the AR ligand-binding domain (LBD) revealed direct binding of minoxidil to the AR in a minoxidil-AR-LBD co-crystal model, and surface plasmon resonance assays demonstrated that minoxidil directly bound the AR with a Kd value of 2.6 ?M. Minoxidil also suppressed AR-responsive reporter activity and decreased AR protein stability in human hair dermal papilla cells. The current findings provide evidence that minoxidil could be used to treat both cancer and age-related disease, and open a new avenue for applications of minoxidil in treating androgen-AR pathway-related diseases.

[blondetooth]

Please people, putting chemicals on your scalp is not healthy.

Don't be one of those people that only believes what a doctor tells them, or only believes what they read on the back of the medicine box.

[blondetooth]

Rogaine: After 48 weeks you are basically baseline....

Propecia works though. Have a good day.

Here is your google search link for Rogaine wrinkles, hundreds of thousands people complaining, dark bags under eyes etc.... https://www.google.com/webhp?sourcei...ine%20wrinkles Scary.

[Ted]

I still can't find any before and after pictures of people getting wrinkles from minox. Please link the pictures you are talking about.

I read that in the study that showed the first graph you posted they stopped using minox after 96 weeks. So it looks like after 96 weeks you are still quite a lot better of with minox than without. The question though is for how long.

[gainspotter]

Of course you're gonna get wrinkles from minox. If you use it then you're going bald. Going bald is stressful. Stress causes wrinkles.

[fred970]

Don't be one of those people that only believes what a doctor tells them, or only believes what they read on the back of the medicine box.

Who are we supposed to believe then? You?!

And another one! Stress causes wrinkles now. First, define stress, secondly, stop writing complete nonsense.

There are no before/after pictures. Therefore, there is no evidence. Therefore, case closed.

I must laugh at the 25 years old men who've used minoxidil for 2 years and say it gave them wrinkles.

Hey, dude, you're ageing, we all are, of course you're going to get some wrinkles at that age. Get over it and stop blaming the minoxidil.

And to people who say that this is a known side-effect, they can scan the notice of Rogaine and show us where it's written in the side-effects. We're waiting.

[asianguy]

Are there any benefits to dermarolling without topicals?

Also will dermarolling help reduce the visibility of FUE donor punch scars?

[FFS]

I know the studies suggest dermarolling til you bleed everywhere but will it be beneficial to use a derma roller daily at 1.5mm but not drawing blood and immediately applying RU afterwards, to enhance absorption of RU?