Why cant they do this for hair follicles? Seriously?

[KO1]

In this case its done with just isolated DS cells. (dermal sheeth).

the isolated cells where able to create scalp hairs. on jahoda's forearm. the beauty of this, is that we can go further, like my first post shows, to make use of the other cells that are trychonic.


"All the wound sites healed rapidly and
lacked any overt inflammatory reaction.
Remarkably, each of the sites of dermalsheath implantation produced new follicles
and fibres 3 to 5 weeks after the graft "

https://www.dropbox.com/s/hzsywst375...0testrabit.pdf

Not including that study. I don't think there's any example of human hair follicles composed of multiplied human DP cells and keratinocytes on human skin, even on SCID mice.

The Jahoda study you linked doesn't involve culturing and multiplication which has been THE challenge, otherwise we know these cells are trichogenic.

[Boldy]

Not including that study. I don't think there's any example of human hair follicles composed of multiplied human DP cells and keratinocytes on human skin, even on SCID mice.

The Jahoda study you linked doesn't involve culturing and multiplication which has been THE challenge, otherwise we know these cells are trichogenic.

we already know how to culture DP cells in longterm, without them loosing the Markers that indicate if they will be trichonic or not. this is not a challenge anymore... 3d culture, aggregating the cells at the end, or even 2d culture with wnt, fgf and bmp2. ..

screening for the genese/ markers and comparing the intact fresh isolated dp vs long term cultured/restored dp, shows same levels, and after implantation same results. I'm very confident about this approach.

[KO1]

I agree the science looks good....but I don't think we've actually seen it happen. ARI never confirmed whether their results were revitalization of follicles or formation de novo.

[Boldy]

I agree the science looks good....but I don't think we've actually seen it happen. ARI never confirmed whether their results were revitalization of follicles or formation de novo.

they haven't bee using dp cells, no serum, and probably no growth factors. all are limiting factors here.

regarding ari's last approach without dp, they aimed for revitalization.This understanding comes from their latest presentation found on youtube.

[KO1]

they haven't bee using dp cells, no serum, and probably no growth factors. all are limiting factors here.

regarding ari's last approach without dp, they aimed for revitalization.This understanding comes from their latest presentation found on youtube.

What cell types did they use then? I'm confident they used both dermal papilla fibroblasts as well as keratinocytes from HF Bulge.

http://www.clinicaltrials.gov/ct2/results?term=ji+gami&Search=Search

Most say dermal and epidermal cells. Unless I am missing something.

[Boldy]

What cell types did they use then? I'm confident they used both dermal papilla fibroblasts as well as keratinocytes from HF Bulge.

http://www.clinicaltrials.gov/ct2/results?term=ji+gami&Search=Search

Most say dermal and epidermal cells. Unless I am missing something.

dermal cells can be dermal sheeth, or dermal sheeth cup.

check this video, https://www.youtube.com/watch?v=l_JHbtXJ0a8

[KO1]

Yeah I've seen the video, but I find it hard to believe they would not use DP cells, ARI themselves developed many of the assays that measure trichogenicity of cultured cells in vitro, so I would think they would use DP cells.....just IMO.

[Boldy]

Yeah I've seen the video, but I find it hard to believe they would not use DP cells, ARI themselves developed many of the assays that measure trichogenicity of cultured cells in vitro, so I would think they would use DP cells.....just IMO.

I think you're right.. just watched the video again..

[Boldy]

I think you're right.. just watched the video again..

they are culturing the cells for just 2 weeks regarding this video., without serum.

I have their patent somewhere, will reread it tomorrow.

[KO1]

That is interesting if the case....Nigam OTOH is culturing bulge stem cells for 6 wks, perhaps DP cells for the same amount.

ARI is likely not using 3d dp cultures as that is newer technology and I think Jahoda/Christiano/Higgins hold the patent there.

[clandestine]

Huh.

Didn't know we were already cured. Who'd have thought?

[ar50]

Wow man you blew my mind: we could really CHOOSE what kind of hair we wanted?
I was happy if i could find something to stop my hair loss haha.

But what do you thinks is the best way to approach the problem of regulations?
What can we do in your opinion?

[DepressedByHairLoss]

Some one else posted this discovery a while ago on this forum: https://www.youtube.com/watch?v=FsxCrv2wuss. If they can multiply skin like this (and use this discovery on a human being), then I wonder why they can't do the same thing with hair follicles.