Human organs could be grown in animals "within a year"

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  • KO1
    Senior Member
    • Jan 2012
    • 805

    #46
    I love these forums.

    Comment

    • FearTheLoss
      Senior Member
      • Dec 2012
      • 1581

      #47
      Originally posted by x4342
      There are a lot of promising technologies but many are of skeptical of the claims.

      -Replipenis claims they can increase size. First the take a small "donor" sample, culture it and inject it back in. Their results with humans have been poor but they have managed to give a lot of mice giant members.

      -Aaaaaderans is a sex toy manufacturer, but they are also working on an eventual similar treatment although there are rumors they are giving up.

      -Another company is working on what they call "PSC", penile stimulating complex. They claim it works but people have criticized the pictures with one doctor at a recent conference stating, "they aren't exactly producing porn star material." A lot of rumors about funding issues with these guys.

      -If you don't want to wait for any of these new treatments you can always go with current stuff. Penisteride seems to work, but it's a highly contentious subject as a lot of guys say it made all their hair fall out.

      Oh, and if you opt for surgery, AVOID THE STRIP METHOD. Just trust me on this one.

      Actually laughed out loud when I saw this reply.

      Comment

      • FearTheLoss
        Senior Member
        • Dec 2012
        • 1581

        #48
        funniest thing I have ever read hands down.

        Comment

        • Thinning87
          Senior Member
          • Dec 2012
          • 839

          #49
          Originally posted by x4342
          There are a lot of promising technologies but many are of skeptical of the claims.

          -Replipenis claims they can increase size. First the take a small "donor" sample, culture it and inject it back in. Their results with humans have been poor but they have managed to give a lot of mice giant members.

          -Aaaaaderans is a sex toy manufacturer, but they are also working on an eventual similar treatment although there are rumors they are giving up.

          -Another company is working on what they call "PSC", penile stimulating complex. They claim it works but people have criticized the pictures with one doctor at a recent conference stating, "they aren't exactly producing porn star material." A lot of rumors about funding issues with these guys.

          -If you don't want to wait for any of these new treatments you can always go with current stuff. Penisteride seems to work, but it's a highly contentious subject as a lot of guys say it made all their hair fall out.

          Oh, and if you opt for surgery, AVOID THE STRIP METHOD. Just trust me on this one.
          HAHAHAHAHAHA very good very good!

          Comment

          • KO1
            Senior Member
            • Jan 2012
            • 805

            #50
            Remember, if you get penis transplant, you know the rules, we want before and after pics from all angles, wet, dry, you name it.

            Comment

            • FearTheLoss
              Senior Member
              • Dec 2012
              • 1581

              #51
              and don't be alarmed when after 2 months you have nothing down there, it will probably start to grow back at about six months..but then there are the unlucky few that just lose it for good...that's where choosing the right doctor really comes into play. Maybe you should go experimental and get a procedure with Nigam? I hear he "doubles the donor"

              Comment

              • ar50
                Senior Member
                • May 2013
                • 115

                #52
                Hahahajaha good one bro. Its good to laugh in this dark period of time for us.
                No but in all fairness: im satisfied but you know i was just wondering.
                There a lot of veterans without an arm or a leg. This could be major breaktrough

                Comment

                • FearTheLoss
                  Senior Member
                  • Dec 2012
                  • 1581

                  #53
                  I don't think this is a dark period of time for us...

                  Histogen: Showed results that are better than minox and fin combined with no major side effects (IN THEIR SAFETY STUDY)

                  RepliCel: Going into phase 2 studies, got a 7 million dollar investment in their hair regeneration technology. (obviously they have something there for this to happen, Spencer has faith in them)

                  Follica: Has grown hair on humans, FGF9 may really boost their results too. Let's stay cautiously optimistic with them because they are working on a real CURE...like this whole thing would be forever over...I guess replicel is too.

                  CB: some forum members have already seen promising results from it and they aren't even using the correct vehicle that was used in the study. If everything goes well, we could see CB to the market in 2016-2017.

                  Topical Fin: Hasson and Wong are already offering it, but not the version with the new film. This has potential because there may be a happy medium where the amount absorbed in the bloodstream is minimal enough to not give us guys with sides, sides...but yet benefit our hair. Time will tell. I contacted HW and they said people have had good results with their topical fin (better than minox, not as good as oral fin, but no sides)

                  PDG2: people are supposedly getting amazing results with this, but again, time will tell. This has good science behind it, so it may be just tweaking the dosage.

                  Dr. Nigam Donor Doubling: We will see where this goes, but I am starting to believe.

                  Dr. Cole: Has been getting 10-70% donor regeneration with Acell, with an average of 50%..but still a 50% increase in donor would make a huge difference.

                  Comment

                  • x4342
                    Member
                    • Apr 2013
                    • 55

                    #54
                    ar50: Sorry about that, bro.. I was just trying to lighten things up! Sometimes we all need a laugh or two.

                    Anyway, it's far easier to provide a scaffold and allow the body to repair itself than completely regrow something. If a soldier severely damages his leg and loses a ton of tissue things can be done. They are making a lot of progress when it comes to restoring lost tissue. But literally giving someone their leg back when it is completely gone is likely still a long way off.

                    FearTheLoss:
                    I agree that Follica has been pretty uncompromising in their approach and desire to find a "problem solved" solution. As consumers we benefit most from a combination of long and shorter term approaches. You need someone that is determined to completely solve the problem in an uncompromising manner but also for others to simply release something that is markedly better than what we have today. If Histogen could simply release an obviously superior product in a timely manner it would be a huge step forward even if it isn't a quantum leap forward.

                    Comment

                    • ar50
                      Senior Member
                      • May 2013
                      • 115

                      #55
                      Originally posted by x4342
                      ar50: Sorry about that, bro.. I was just trying to lighten things up! Sometimes we all need a laugh or two.

                      Anyway, it's far easier to provide a scaffold and allow the body to repair itself than completely regrow something. If a soldier severely damages his leg and loses a ton of tissue things can be done. They are making a lot of progress when it comes to restoring lost tissue. But literally giving someone their leg back when it is completely gone is likely still a long way off.

                      FearTheLoss:
                      I agree that Follica has been pretty uncompromising in their approach and desire to find a "problem solved" solution. As consumers we benefit most from a combination of long and shorter term approaches. You need someone that is determined to completely solve the problem in an uncompromising manner but also for others to simply release something that is markedly better than what we have today. If Histogen could simply release an obviously superior product in a timely manner it would be a huge step forward even if it isn't a quantum leap forward.



                      No problem man haha i found it very original
                      What really amaze me is fact that there is still no real treatment for hairloss( im talking about people who dont want to use fin, because for the fin users there is obviously a treatment). They are working on cloning a ****ing mammoth but hair loss is to hard. They can now transplant heads, but hair loss is to hard.

                      I am no scientist and this is probably more about financing and priorities but Thats's the thing what really irritates me.

                      And what also bugs me is that follica is so quiet about their research. I mean okay you dont want the competition to find something out but at least give us some more info. I really clinge on the positive news i read on this forum, because I have lost a lot of my confidence.

                      But back on subject: is Histogen safe? I remember I read that you only can injected once because it can have bad effect?

                      Comment

                      • KO1
                        Senior Member
                        • Jan 2012
                        • 805

                        #56
                        Originally posted by ar50
                        But back on subject: is Histogen safe? I remember I read that you only can injected once because it can have bad effect?
                        It should be safe, but the problem is that continuous activation of Wnt can lead to bad things, like cancer, but the safety profile is really unknown at this point in time.

                        I've followed Follica for years now, and to my knowledge, they're currently growing primitive, follicle-like structures called "neogenic-like hair follicles", and they haven't clearly elucidated the relationship between those and terminal follicles. Their P2 control group data showed roughly 11% growth with JUST dermabrasion btw, so you'd think with activation of Wnt, upregulation of FGF, and suppression of PGD2, we should see SOMETHING.

                        Comment

                        • yeahyeahyeah
                          Senior Member
                          • Nov 2011
                          • 1776

                          #57
                          Originally posted by KO1
                          It should be safe, but the problem is that continuous activation of Wnt can lead to bad things, like cancer, but the safety profile is really unknown at this point in time.

                          I've followed Follica for years now, and to my knowledge, they're currently growing primitive, follicle-like structures called "neogenic-like hair follicles", and they haven't clearly elucidated the relationship between those and terminal follicles. Their P2 control group data showed roughly 11% growth with JUST dermabrasion btw, so you'd think with activation of Wnt, upregulation of FGF, and suppression of PGD2, we should see SOMETHING.
                          What phase are they in? And how long before its released?

                          Comment

                          • ar50
                            Senior Member
                            • May 2013
                            • 115

                            #58
                            I've followed Follica for years now, and to my knowledge, they're currently growing primitive, follicle-like structures called "neogenic-like hair follicles", and they haven't clearly elucidated the relationship between those and terminal follicles. Their P2 control group data showed roughly 11% growth with JUST dermabrasion btw, so you'd think with activation of Wnt, upregulation of FGF, and suppression of PGD2, we should see SOMETHING.[/QUOTE]

                            woow bro im sorry but i dont understand a word you said haha : try to explain this to your friend who doesnt know anything about hair loss.

                            Comment

                            • KO1
                              Senior Member
                              • Jan 2012
                              • 805

                              #59
                              Originally posted by yeahyeahyeah
                              What phase are they in? And how long before its released?
                              Follica finished Phase2 two years ago. They have not commented further.

                              Comment

                              • KO1
                                Senior Member
                                • Jan 2012
                                • 805

                                #60
                                Originally posted by ar50
                                woow bro im sorry but i dont understand a word you said haha : try to explain this to your friend who doesnt know anything about hair loss.
                                Basically sandpapering your head will grow some hair. Follica is trying to make a treatment that involves sanding your head+topical lotion = hair.

                                Try to remember, Follica is growing mini organs de novo. This is real breakthrough stuff, and obviously extremely difficult. If they crack this, this has serious, broad ranging implications. I dont know about penis translplants though. Just messing with you.

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