Histogen's FINAL Phase I/IIa Results (2013)

[UK_]

Ok, one thing I don't get is that the same toxicology data was on the 6 month poster that Histogen produced yet nobody mentioned it, everyone was thrilled with Histogen when they released the 6 month data.

Yes that's true it was revealed in October but not many people mentioned it.

[Desmond84]

Really! I must have missed it!

The follistatin is the culprit! Who knows they might take it out of their formula in order to allow fir increased dosing!

How vital is follistatin for hair growth is anyones guess

[UK Boy]

I just feel people may have jumped on this cos Desmond pointed things out to them, Desmond said Histogen's dead and suddenly it's gospel even though certain elements of the info have been sitting there for 6 months and no one even questioned then. Gail mentioned they're carrying out toxicology testing on large mammals so they appearing to be looking into this issue and hopefully trying to resolve it. I really think we need more info from the company regarding the results before Histogen gets written off, remember they still haven't even got into optimal dosing so efficacy can improve. On a side note I don't think people should be writting Aderans off yet either, it's been like 1 month since their last phase 2 trial ended, you need ta give them at least 2 months to analyse results and get a statement organised. Everyone's gone doom and gloom but I feel it's an over reaction. Histogen and Aderans will not be miracle cures but they could be helpful tools if the companies don't try to charge large amounts for them.

[garethbale]

I just feel people may have jumped on this cos Desmond pointed things out to them, Desmond said Histogen's dead and suddenly it's gospel even though certain elements of the info have been sitting there for 6 months and no one even questioned then. Gail mentioned they're carrying out toxicology testing on large mammals so they appearing to be looking into this issue and hopefully trying to resolve it. I really think we need more info from the company regarding the results before Histogen gets written off, remember they still haven't even got into optimal dosing so efficacy can improve. On a side note I don't think people should be writting Aderans off yet either, it's been like 1 month since their last phase 2 trial ended, you need ta give them at least 2 months to analyse results and get a statement organised. Everyone's gone doom and gloom but I feel it's an over reaction. Histogen and Aderans will not be miracle cures but they could be helpful tools if the companies don't try to charge large amounts for them.

Spot on.

Nobody here has any inside information on any of these companies...Replicel, Aderans, Histogen, Nigam etc.

As soon as it is mentioned that there is a problem, or that a trial hasn't grown an afro on a patient, this forum goes into meltdown! Yes, the figures don't look great but really what are we expecting? If Histogen can maintain for a good few years with injections that is still a very good option for some people (like me, who don't respond much to fin)

Lets not jump for joy when we hear potentially encouraging news nor bemoan our fate when we don't. This is going to be a long drawn out process and there will many more ups and downs.

[Desmond84]

You're right! It was there! Im amazed that no one questioned it!

I guess all drugs have a therapeutic window...there is only so much of a drug we can administer without causing toxicity!

Its the same with Histogen! Back in october some members calculated that we need 250-300 shots to cover the entire nw5 pattern area!

Now that is a significant amount of hsc to inject! I said it before...the results are decent...but you will still need a dht inhibitor to maintain the areas you didnt inject...

I was just pointing out that this will not be an alternative to propecia but rather an add-on or a better version of minoxidil

[UK_]

I just feel people may have jumped on this cos Desmond pointed things out to them, Desmond said Histogen's dead and suddenly it's gospel even though certain elements of the info have been sitting there for 6 months and no one even questioned then. Gail mentioned they're carrying out toxicology testing on large mammals so they appearing to be looking into this issue and hopefully trying to resolve it. I really think we need more info from the company regarding the results before Histogen gets written off, remember they still haven't even got into optimal dosing so efficacy can improve. On a side note I don't think people should be writting Aderans off yet either, it's been like 1 month since their last phase 2 trial ended, you need ta give them at least 2 months to analyse results and get a statement organised. Everyone's gone doom and gloom but I feel it's an over reaction. Histogen and Aderans will not be miracle cures but they could be helpful tools if the companies don't try to charge large amounts for them.

Sorry but I have written everyone off. Its over guys, lets stop the madness.

[garethbale]

Sorry but I have written everyone off. Its over guys, lets stop the madness.

Cheer up UK

[Pentarou]

Someone like UK_ who has been round on these forums for longer would have a more realistic perspective on "future" hair loss treatments, as in they ain't going to happen.

We all need to immediately adjust our way of thinking - it won't be if we go bald, it is when, and all we can realistically ever hope to do in our lifetimes is to delay that "when" to a slightly later date.

[UK_]

There comes a time in every bald truthers life that he has to accept the obvious.

Its over guys. We're done.

[TO YOUNG TO RETIRE]

pecimists,

i am sorry,

aint Nigam doubling already in the market? why so negative,
get a job save,


AND GET YOUR HAIR

[clandestine]

Someone like UK_ who has been round on these forums for longer would have a more realistic perspective on "future" hair loss treatments, as in they ain't going to happen.

We all need to immediately adjust our way of thinking - it won't be if we go bald, it is when, and all we can realistically ever hope to do in our lifetimes is to delay that "when" to a slightly later date.

A fool who has been around a while is still a fool.

[Desmond84]

OK, I just finished watching Game of Thrones! What on earth!!!!

This week just keeps getting worse!

[ihavebeenchosenithasbegun]

There comes a time in every bald truthers life that he has to accept the obvious.

Its over guys. We're done.

Pretty much we're probably going to be the last or second last generation to get ****ed.

Well, it seems finasteride is indeed sent by the gods, no matter how crude it is.

[Thinning87]

I just feel people may have jumped on this cos Desmond pointed things out to them, Desmond said Histogen's dead and suddenly it's gospel even though certain elements of the info have been sitting there for 6 months and no one even questioned then. Gail mentioned they're carrying out toxicology testing on large mammals so they appearing to be looking into this issue and hopefully trying to resolve it. I really think we need more info from the company regarding the results before Histogen gets written off, remember they still haven't even got into optimal dosing so efficacy can improve. On a side note I don't think people should be writting Aderans off yet either, it's been like 1 month since their last phase 2 trial ended, you need ta give them at least 2 months to analyse results and get a statement organised. Everyone's gone doom and gloom but I feel it's an over reaction. Histogen and Aderans will not be miracle cures but they could be helpful tools if the companies don't try to charge large amounts for them.

Spot on.

Nobody here has any inside information on any of these companies...Replicel, Aderans, Histogen, Nigam etc.

As soon as it is mentioned that there is a problem, or that a trial hasn't grown an afro on a patient, this forum goes into meltdown! Yes, the figures don't look great but really what are we expecting? If Histogen can maintain for a good few years with injections that is still a very good option for some people (like me, who don't respond much to fin)

Lets not jump for joy when we hear potentially encouraging news nor bemoan our fate when we don't. This is going to be a long drawn out process and there will many more ups and downs.

I agree. Having been bald and seen many letdowns for a long time doesn't make anyone more knowledgeable about future treatments than anybody else.

I can't believe all the sudden you guys are writing off Histogen like it had promised complete regrwoth in one sitting. If that's what you thought you obviously weren't paying attention to the information out there.

Not only do final results change nothing in terms of what someone can expect from the product, but they confirm to us that the company is indeed moving forward.

And so is Replicel, which was supposed to be dead according to the many "experienced" long-timers. And then we still need to hear anything from Aderans. And in the meantime while all this develops, we got others working in the background. And even if all this doesn't work, we can always shave heads, or get a good HT - life will move on.

So cheer up everybody, new weapons are on their way to being released, so keep at it with the three P's of hairloss because they have not changed: Propecia, Propecia, Propecia.

[The Alchemist]

OK, I just finished watching Game of Thrones! What on earth!!!!

This week just keeps getting worse!

Hahaha! I thought it was quite appropriate - the Starks were a nice metaphore for the hope of baldies everywhere.