Complete RU58841 Usage Guide

[Amercancer]

Ok I got it, just confused from other users.

[Plan C]

My RU arrived today from Anagen and the first thing I noticed is that it doesn't smell of anything, whereas the RU I bought 7 months ago from them smells strongly of chemicals. Hope they're not reducing the potency of it.

[lilpauly]

Some batches smell some don't

[lilpauly]

the solvent causes the smell.

[Swooping]

Indeed smell can differ due to other solvents used in the synthesis process, says nothing about purity. That said kane has been tested several times and is legit as hell don't worry.

[inbrugge]

Thanks for the confirmation guys.

I just ordered a batch from Kane as well. I'm planning to switch from Topical Fin to Ru. I had initially tried Ru at a low dose (20 mg) and quit because I freaked out from the sides. But I'm getting the same sides on Topical Fin, which I'm now tolerating through, so I might as well tolerate through the sides on Ru.

What do you guys say about that? Good or Bad idea to switch from topical fin to Ru? Or keep using both? Should I ease of topical fin or cut cold turkey?

[lilpauly]

Thanks for the confirmation guys.

I just ordered a batch from Kane as well. I'm planning to switch from Topical Fin to Ru. I had initially tried Ru at a low dose (20 mg) and quit because I freaked out from the sides. But I'm getting the same sides on Topical Fin, which I'm now tolerating through, so I might as well tolerate through the sides on Ru.

What do you guys say about that? Good or Bad idea to switch from topical fin to Ru? Or keep using both? Should I ease of topical fin or cut cold turkey?

well gyno is serious side effect

[inbrugge]

well gyno is serious side effect

well I wasn't on Ru long enough to see if Ru also gives it to me. Ru gave me problems downstairs and I quit immidieately instead of seeing how it would fold out.

For topical fin, I've been on it 5-6 weeks and downstairs is better than Ru but it does make my breast more puffy. I think my body is also very susceptible to it. However, when I lay off topical fin for 3-4 days it gets better so I know it's not permanent.

[lilpauly]

well I wasn't on Ru long enough to see if Ru also gives it to me. Ru gave me problems downstairs and I quit immidieately instead of seeing how it would fold out.

For topical fin, I've been on it 5-6 weeks and downstairs is better than Ru but it does make my breast more puffy. I think my body is also very susceptible to it. However, when I lay off topical fin for 3-4 days it gets better so I know it's not permanent.

for some people sides go away after a week or sometimes sides can develope as u get older . Many times Peopke tolerate fin for years then get sides . I have gyno presently from steroids and its really starting to hurt

[Swooping]

Thanks for the confirmation guys.

I just ordered a batch from Kane as well. I'm planning to switch from Topical Fin to Ru. I had initially tried Ru at a low dose (20 mg) and quit because I freaked out from the sides. But I'm getting the same sides on Topical Fin, which I'm now tolerating through, so I might as well tolerate through the sides on Ru.

What do you guys say about that? Good or Bad idea to switch from topical fin to Ru? Or keep using both? Should I ease of topical fin or cut cold turkey?

I would just trial & error if I were you and assess which one works better and which one brings more sides to the table. Then decide for yourself which one is more worth it. That is what I would do.

[inbrugge]

I would just trial & error if I were you and assess which one works better and which one brings more sides to the table. Then decide for yourself which one is more worth it. That is what I would do.

I think I like the science behind Ru better than Fin. I think Ru is designed to bind to receptors where fin is designed to stop all conversion of 5-a? Thus, fin is designed to be systematic for it to be effective where Ru is designed to be localized. Correct me if I'm wrong.

So I have 2 questions:

1. Any thing I should consider if I want to make a compound mix of Minoxidil, Ru, Tretinoin, and etc.

2. What's the best vehicle? Eth+PG, KB, or Neogenic?

[diffuseloser]

Hard to tell. It's all trial and error and what works for some may not necessarily work for others. All you can do is take your time with the prep, whatever vehicle you use. I've just about run out of RU but will be buying another 10g and continue using with Kirkland as it certainly hasn't hurt none. I use minoxidil anyway so it's convenient for me and I've been maintaining quite well. Good luck whatever you decide.

[Swooping]

I think I like the science behind Ru better than Fin. I think Ru is designed to bind to receptors where fin is designed to stop all conversion of 5-a? Thus, fin is designed to be systematic for it to be effective where Ru is designed to be localized. Correct me if I'm wrong.

So I have 2 questions:

1. Any thing I should consider if I want to make a compound mix of Minoxidil, Ru, Tretinoin, and etc.

2. What's the best vehicle? Eth+PG, KB, or Neogenic?

Yes well it binds to the androgen receptors so it will prevent androgens from binding, including DHT. It doesn't mess with 5ar2. But you are correct where RU is designed to act locally, finasteride acts systematically. I think vehicles are indeed as said more of a trial & error what works best for you.

[Boldy]

Yes well it binds to the androgen receptors so it will prevent androgens from binding, including DHT. It doesn't mess with 5ar2. But you are correct where RU is designed to act locally, finasteride acts systematically. I think vehicles are indeed as said more of a trial & error what works best for you.

swoop did you find any data that indicate the binding Time on the AR? I have not this far.

we know that it is about 1 hour in serum, and this can probably be reduced maybe to half with st johns or other p-glycoproteine abc transporters inducers.

[Swooping]

swoop did you find any data that indicate the binding Time on the AR? I have not this far.

we know that it is about 1 hour in serum, and this can probably be reduced maybe to half with st johns or other p-glycoproteine abc transporters inducers.

No I never discovered how long RU58841 stays bound to the androgen receptor. But I suppose it would be close to 24 hours. I tried 2 time applications a day and didn't notice a difference.