Hellouser's RU Log (with Minox, CB Nizoral and Saw Palmetto)

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  • doke
    Senior Member
    • Jun 2009
    • 1464

    Originally posted by hellouser
    Many of you have seen me post and boast about RU and many of you have also inquired about my progress... well, here is my log.

    I noticed my hair going bad.. I mean really bad back in around March of 2011. I didn't notice it thin out or anything, but rather my hair line go waaaay back than what it used to be. I noticed this after I was at a club with friends and had some pictures of myself taken. The lighting on my face was rather harsh and it exposed a lot of scalp behind the hairline which made the hairline look higher than it actually is. This is where my life started going downhill..... its when I realized I looked ****ing weird and it was my hair. By this time I was already an NW2-3, but I never really took much notice into my hairline.. I didn't care about it before, I thought I looked normal (I mean I still do, but society is full of shithead assholes so no, by their standards I dont look normal).

    February, 2011 - Before Regimen
    So I started reading about things that can be done. I learned about Saw Palmetto, Nizoral, Finasteride, hair transplants and Replicel. I read about Finasteride castrating men and giving many side effects and it was a complete write off. It still is and its a dangerous drug which no man should take. I'm not saying I'd take it away from those who are already on it with results, but Finasteride is pure bullshit. My first line of defense? Saw Palmetto, and even with that I was hesitant as I ready about mild effects. But the bad breathe issue was the worst problem. It subsided eventually though.

    Here's what my hair looked like then (these are from a club, so apologies for the crappy quality). Mind you, I used to use a good but 'wet' product called Bedhead by Tigi. This makes hair look quite thin as it climps hair real close together, hence it looking thin below.







    So here's where I start fighting this disease that nobody cares about;

    April, 2011
    I start taking saw palmetto. Did my research, relatively small sides if any, much safer than finasteride, 1 pill a day (eventually moved up to 2 pills a day, 160mg each). Also started using Nizoral.

    June, 2011
    I start taking Kirkland's Minoxidil 2%, twice a day. I suppose in the pics below I shed a bit however I don't remember freaking out about hairs in the tub or on my pillow.





    October, 2011
    Ordered 5grams of RU from Ontario Chemicals and start using in 1ml application of 0.7ml isopropyl (wrong vehicle) and 0.3ml of PG. Concentration of RU was probably about 10mg. USELESS. At this dosage, almost impossible to get side effects more so since I was using isopropyl.
    RU is now applied once daily, Minoxidil once daily as well.

    March, 2012
    In the picture below I am 5 months into using 1ml of RU with about 1-2% concentration (10-20mg) with about 1ml of Minoxidil at 2%. I should mention that while I'm on this regimen, I often used only 0.5ml total per day which all went into my hairline. The rest of my pathetic head I battled with Minox.



    September, 2012
    Ran out of 5g of RU (yeah, after 11 months). Order 10g of RU from Ontario Chemicals again, still using Isopropyl but upped the dosage of RU to 5% concentration per 1ml (so 50mg per 1ml) and used once daily. Still on Minoxidil 2% once daily, still on Saw Palmetto and Nizoral.

    No further loss, no shedding still but no regrowth either.

    October, 2012
    Below we can see I've had regrowth!





    December, 2012
    Ran out of 2% Minoxidil from Kirklands, changed it to Kirklands 5%.

    MASSIVE SHEDDING (therefor, major loss in density).

    Hair got thinner immediately in the following weeks.
    Still on RU at 5% in 1ml, Saw Palmetto and Nizoral.

    January, 2013
    Below is a photo of my hair RIGHT after a lot of Minox was applied all over and we see a drastic change for the worse. The shedding from the switch to Minoxidil at 5% is evident and things look terrible. Mind you in the photos below I am using between 1.5-2ml of Minoxidil and these pictures are IMMEDIATELY after application hence my hair looks wet and thin.





    February 6th, 2013
    Photos below show whats going on:



    February 15th, 2013
    STILL SHEDDING and most likely due to going from 2% to 5% minoxidil. Shedding is common and usually a sign of efficacy. Ran out of RU, got 10g again of RU, but also purchased Everclear to fix the vehicle. Upped the dosage of RU to about 100mg per 1ml (thus 10% solution) once daily.



    Below it is very VERY clear I've lost a lot of density.




    March, 2013
    Shedding slowing down significantly. No regrowth yet however small hairs have shown up around the hairline.

    April 19th, 2013
    Havent had a haircut since January/February so hair is quite long. Still shedding. But: LOTS of new hairs have sprouted around the hairline and the small hairs at hairline visible 1 month prior are now longer, but only visible when seen up close. I hope the same holds true for the vertex and crown to hold onto my hair until Aderans/Histogen is out.





    April 20th, 2013
    Day of haircut! Behold! Density is back!





    Currently:
    Today is May 1st, and I recently added CB once daily at 1% (1-1.5ml) thus the new regimen is now:

    100mg RU in 1ml, once daily
    10-15mg CB in 1ml or 1.5ml, once daily
    Minoxidil 5% at about 1.5ml, once daily
    Saw Palmetto (320mg - 550mg daily, depending on available pills)
    Nizoral 2%

    I'm also using some shampoos with Saw Palmetto and am planning on acquiring MiN New York hair products (a clay which contains saw palmetto and azelaic acid, probably useless but better than nothing).

    I've also noticed THICK and DARK terminal hairs show up at the hairline! These are hairs I dont remember seeing from a while back and potentially havent been around in years! There aren't many, maybe about 20, but its a clear sign things are working.

    Future treatment:

    I recently acquired Lubrajel, the same vehicle used in the study for BNP-32 as a topical treatment for hair loss. You can read about this peptide here or my general summary here

    I have quite a bit of cash saved up for a surgical treatment for Dr. Gho, but if the guys from other forums already experimenting with BNP-32 get results, I will be buying some BNP-32 myself and using my lubrajel to regrow the temples and entire scalp. If that fails, its Gho time (or someone else that can offer regeneration).

    - - - - - - - - - - - - - - - - - - - - - - - - - - - -

    I do want to say though that the last two years of my life have EASILY been the most depressing, most angry, most lacking. I'm trying to wait very patiently for a treatment from Histogen and Aderans.

    If anyone is curious about how effective is CB? I don't know yet, its too soon to tell.

    As for side effects? None from RU as far as I can tell. No brain fog, no limp-finasteride-dick however I have experienced many drops in Libido from Saw Palmetto. Whats weird is that sometimes my libido is RAGING high and I'll be getting random stiffies at work too. Though I suppose the reduced libido could also be due to physical inactivity and general depression.

    I hope this helps. I'll post more in the future.

    Also, if anyone wants to know how to acquire, mix, apply, etc RU, I've made a complete guide here; http://www.baldtruthtalk.com/showthread.php?p=120497
    hi hell many thanks for this post i only just found it and holy cow there is a massive improvement have you tried spironolactone 5% cream? and im now wondering whether to reuse my 5% mpb treatments ru plus with 5% minox not sure if i can afford cb as well.
    If i could get back what you have done i would be very happy to what i have now although im a lot older than you hell.
    This shedding you went through looks the same as irishpride had but turned it around like you,if we have to keep going through major sheds it will suck.
    Do you think you have the right combo now hell?

    Comment

    • doke
      Senior Member
      • Jun 2009
      • 1464

      Is cb like ru?

      Comment

      • HARIRI
        Senior Member
        • Nov 2012
        • 467

        Originally posted by doke
        Is cb like ru?
        I asked the same question and two members answered me well:-

        yan answer:-

        "In preclinical studies, CB-03-01 was shown to be rapidly metabolized by the skin to the parent compound cortexolone, which is a physiological steroid lacking anti-androgen activity and is completely safe."

        "Cortexolone has good penetrative properties, making it suitable for topical use, and while effective locally it is metabolized into a harmless, inactive parent compound prior to circulating systemically"

        RU keeps its anti-androgen property, even after passing the skin and going systemic.

        Lothar99 answer:-

        CB-03-01 is an androgen receptor blocker, meaning that it will bind to androgen receptors and therefore prevent other things from binding (mostly we are concerned with DHT binding). There are other medications that have this method of action, but what makes CB-03-01 unique is that it is quickly metabolized when it enters the bloodstream. Ideally, you apply the CB-03-01 to the scalp, and as it passes through the skin, it binds to the androgen receptors there. Any CB-03-01 that passes all the way through to the blood will metabolize into a substance that doesn't block androgen receptors. Because it is so quickly metabolized, the CB-03-01 should never reaches other parts of the body where it would cause androgen related side effects.

        Comment

        • The Dark Knight
          Member
          • Aug 2012
          • 38

          Does anyone know where to get ethanol in the UK? It seems everclear alcohol is illegal here and there is no way to import it

          Comment

          • HARIRI
            Senior Member
            • Nov 2012
            • 467

            Originally posted by The Dark Knight
            Does anyone know where to get ethanol in the UK? It seems everclear alcohol is illegal here and there is no way to import it
            That is the biggest challenge. Where to get Ethanol/PG online? Unfortunately MPB Treatments looks like they are a rip off as COB984 ordered several bottles from them but didn't get any while his credit card got deducted already. I hope one member may become kind enough to search online for them.

            Comment

            • moore
              Member
              • Jun 2012
              • 95

              Originally posted by HARIRI
              Lothar99 answer:-

              CB-03-01 is an androgen receptor blocker, meaning that it will bind to androgen receptors and therefore prevent other things from binding (mostly we are concerned with DHT binding). There are other medications that have this method of action, but what makes CB-03-01 unique is that it is quickly metabolized when it enters the bloodstream. Ideally, you apply the CB-03-01 to the scalp, and as it passes through the skin, it binds to the androgen receptors there. Any CB-03-01 that passes all the way through to the blood will metabolize into a substance that doesn't block androgen receptors. Because it is so quickly metabolized, the CB-03-01 should never reaches other parts of the body where it would cause androgen related side effects.
              This is one of the best and clearer explanation I've ever read.
              Wonder if someone has ever raised the question: DHT blockers would stop DHT from miniaturizing follicles not already fallen to the vellus stage (right or wrong?).
              What about the already vellus ones?
              I know maybe this is not the right thread where to ask..sorry.
              Every time I read about this very subject I'm frightened by words such as 'fibrosis':





              http://www.****************/interact...an-be-reverted

              Comment

              • Avacfc
                Member
                • May 2013
                • 31

                Originally posted by The Dark Knight
                Does anyone know where to get ethanol in the UK? It seems everclear alcohol is illegal here and there is no way to import it
                I live in the uk and had a hard time finding ethanol or a high percent alcohol since its not sold above 40% here. However i dug deep and found a 95% polish vodka for 30 quid online. Not sure if im aloud to give out website on here

                Comment

                • doke
                  Senior Member
                  • Jun 2009
                  • 1464

                  Originally posted by Avacfc
                  I live in the uk and had a hard time finding ethanol or a high percent alcohol since its not sold above 40% here. However i dug deep and found a 95% polish vodka for 30 quid online. Not sure if im aloud to give out website on here
                  i found same problem had to buy polish vodka and its expensive.

                  Comment

                  • HARIRI
                    Senior Member
                    • Nov 2012
                    • 467

                    Originally posted by doke
                    i found same problem had to buy polish vodka and its expensive.
                    I think the only way to get it is from MPBtreatments, they sell each bottle of ethanol/PG for $7 only. My forum friend COB984 received a confirmation of shipping from them just today. I hope he could share more info about it. Seems like they are legit but slow!!!

                    Comment

                    • The Dark Knight
                      Member
                      • Aug 2012
                      • 38

                      Originally posted by Avacfc
                      I live in the uk and had a hard time finding ethanol or a high percent alcohol since its not sold above 40% here. However i dug deep and found a 95% polish vodka for 30 quid online. Not sure if im aloud to give out website on here
                      Yeah, its ridiculous how hard it is to find here but thanks! I searched 95% vodka online and I think I've found it

                      Comment

                      • doke
                        Senior Member
                        • Jun 2009
                        • 1464

                        Now guys reflecting on cb 03-01 a drug that may be helpful for acne and alopecia androgenica but i remember this antiandrogen talk for many years with what some called the mother of all antiandrogens ru58841 now we have some access to it with a ready made mpb treatments formula and kanes powder its gone off the boil so i like others went out and bought some powder and also mpbs ready made is it a miracle no its not and this maybe the same hard to get hold of and is it the right mix we will not be sure until cosmo makes it available.
                        Talk has it that for acne tretinoin is a better treatment and we know that cannot be used if you go out in the sun so best apply at night spectral dnc L has it in its formula and also dr lewenbergs famous 2% minoxidil+tretinoin formula that has many regrow there hair on.
                        I Think it better to wait until the hype dies down and see if anyone regrows hair back with cb i hope it does work.

                        Comment

                        • Avacfc
                          Member
                          • May 2013
                          • 31

                          Originally posted by The Dark Knight
                          Yeah, its ridiculous how hard it is to find here but thanks! I searched 95% vodka online and I think I've found it

                          This is what i got

                          Comment

                          • hellouser
                            Senior Member
                            • May 2012
                            • 4419

                            Originally posted by Avacfc
                            That will work

                            Comment

                            • HARIRI
                              Senior Member
                              • Nov 2012
                              • 467

                              Here you go Guys, I got this link from the Kane Shop:-



                              They do have both:-

                              PHARMA GRADE 98% ETHANOL 50ML...$7 Only

                              PHARMA GRADE 98% ETHANOL 100ML... $11 Only

                              Comment

                              • nliyan25
                                Member
                                • Jul 2013
                                • 44

                                RU shed

                                Hellouser, is it normal to be losing about 50 hairs a day on RU after two weeks? Should this decrease with time? Also, is RU supposed to thicken existing hair that is thin?

                                Comment

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