Finasteride 0.25 mg twice per week. Works for me.

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  • Notcoolanymore
    Senior Member
    • Jun 2013
    • 2246

    #91
    Originally posted by kissmyscalp
    Yes, I look like Kim kardashian now. I plan to stop this crap. This is not a viable solution.

    Nice, mmmm hmmm.

    Comment

    • JulioGP
      Senior Member
      • Feb 2013
      • 293

      #92
      Originally posted by kissmyscalp
      I'm on 0.25 mg EOD from 4 month and it completely stop my hair loss so stop saying sh*t. It works, probably not for everyone, but it works.

      Fin reduce DHT for 48h at almost the same amount so no problem and 0.25mg is at least 50% as powerful as 1mg.

      And I have some sides too: testicular pain, breast sensibility and weight gain.

      I'm sorry but you are wrong.

      You did not actually read the package insert for Finasteride?

      Pharmacokinetic data

      Bioavailability
      63%

      Metabolism
      Hepatic

      Half-life
      Elderly: 8 hours
      Adults: 6 hours


      Excretion
      Feces (57%) and urine (39%) as metabolites

      Comment

      • Jazz1
        Inactive
        • Aug 2012
        • 1598

        #93
        I tested FIN every third day was fine, anything over 3 days my itch would come back. Iv been on FIN EOD and been doing fine.

        Comment

        • kissmyscalp
          Member
          • Dec 2013
          • 42

          #94
          From a doctor on another website:

          The average serum "half-life" of finasteride 1mg is about 5 hours in young men and 8 hours in older men. This does not mean that half of the medicine is out of your body in that time period though. The finasteride molecule is distributed throughout the body where it binds to the type II 5-alpha-reductase enzyme, thereby inhibiting conversion of testosterone to dihydrotesterone. Serum DHT is reduced about 65%, and less DHT means less balding. But several studies show that a single dose of finasteride suppresses serum DHT for 7 days or more (Eur J Drug Metab Pharmacokinet. 1991 Jan-Mar;16(1):15-21, J Clin Endocrinol Metab. 1990 Apr;70(4):1136-41, Prostate. 1989;14(1):45-53). So the finasteride is leaving the bloodstream, entering the tissue throughout the body, and binding to the typeII 5AR enzyme, resulting in long lasting DHT suppression.

          I do not "recommend" my patients take finasteride daily, every other day, twice weekly, etc. Rather I feel it is my duty as their doctor to advise them of the known facts about this medication. Most of my patients choose to take it on a Mon-Wed-Fri schedule, which is rational from my point of view. Many of my younger patients take it daily 'just to be sure' while my older patients are happy to take it two or three times a week. There are no clinical studies showing that less than daily dosing is as effective at treating hair loss as daily dosing and for obvious financial reasons, the pharmaceutical company making finasteride has no incentive to fund such a study.

          Comment

          • JulioGP
            Senior Member
            • Feb 2013
            • 293

            #95
            Look, doctors can say what they want. I've done the blood test (serum) taking finasteride every other day and 1 day after taking the dose, the DHT was already on high again.

            People may feel some improvement and I believe, for 7 days a week if you use 2 times a week, you'll be the other 5 with high DHT. At least 2 days of the week you will remove some DHT. This gives 96 days per year, which is not bad.

            Some people even using Finasteride every day (and doing tests to find it) can download the DHT to an acceptable level, who uses 1 or 2 times a week, will never achieve this.

            Here I make a bet with you.
            Who want to use this way, MAKE TESTS BLOOD. Then post the results here. You will see that does not work.

            Talking about A or B without doing any blood work and believe that it works, is the same as believing in Santa Claus, I'm sorry.

            Comment

            • Jcm800
              Senior Member
              • Jan 2011
              • 2614

              #96
              So Julio, have you had persistant side effects after quitting Finasteride? How many times have you tried the drug yourself?

              I like your posts and believe you talk sense, do you work in the medical field at all?

              Comment

              • kissmyscalp
                Member
                • Dec 2013
                • 42

                #97
                Something is wrong with your blood test. With 1mg ED you have a strong decrease in testo and an increase DHT. This is a complete non sense.

                Maybe you are playing too much with your hormones and different products.

                And DHT does not return to its baseline in only 24h.

                Comment

                • JulioGP
                  Senior Member
                  • Feb 2013
                  • 293

                  #98
                  Originally posted by Jcm800
                  So Julio, have you had persistant side effects after quitting Finasteride? How many times have you tried the drug yourself?

                  I like your posts and believe you talk sense, do you work in the medical field at all?
                  I tried using the product 3 times. I do not work in the medical field. I believe I managed to recover about 85% of what I was before the medication, and it took at least another 6 months. There are many people on the forum here in Brazil (over 8000 participants) had irreversible side effects and still failed to recover.

                  Comment

                  • Jcm800
                    Senior Member
                    • Jan 2011
                    • 2614

                    #99
                    I see thanks, yeah persistant sides are a big worry for me.

                    What sides did you experience that made you try it three times unsuccessfully?

                    Comment

                    • JulioGP
                      Senior Member
                      • Feb 2013
                      • 293

                      Originally posted by kissmyscalp
                      Something is wrong with your blood test. With 1mg ED you have a strong decrease in testo and an increase DHT. This is a complete non sense.

                      Maybe you are playing too much with your hormones and different products.

                      And DHT does not return to its baseline in only 24h.
                      kissmyscalp , DHT returns to its level before 24 hours. Both testosterone and the DHT hormones are very dynamic , they vary quickly up and down.

                      If you collect the blood in the morning and afternoon , may be surprised at the difference in the results because all day these hormones rise and fall, so without having to use any medication.

                      Of course there is much good sense in believing in the package leaflet saying that the half - life of the drug is about 6-8 hours.

                      When you use Finasteride and suppresses DHT , you can have an increase in testosterone or 17 beta - estradiol . Generally the testosterone that was not converted to DHT by the 5AR turns into a bit of estradiol and it is easy to be felt by some, which is the famous Gynecomastia .

                      I had no drop in testo used as Finasteride , however , in my tests, at the time I used 0.5 mg of finasteride every day, I had an increase in testosterone by 32% .

                      Want further proof that DHT quickly returns to its original level within a few hours ? I'll give you an example . Female Contraception .

                      The Contraceptive contains " ingredients " that reduce the release of follicle- stimulating and luteinizing hormones . If the woman does not take all day ( even at the right time ) , does not work properly . It is very similar to DHT. The body does not take days to raise their level, it does not exist.

                      What could perhaps be used for a "long period" would be this:
                      A male contraceptive whose effects last 10 years or more is now in the final stage of trials - and its developers claim it can also regenerate a man's hair and prevent prostate cancer.


                      But there chances of you having side effects for years, since the drug is in your body all this time.

                      Comment

                      • Dan26
                        Senior Member
                        • Jul 2012
                        • 1270

                        Julio you are ONE person...We cannot take your blood test results and say the same will be true for everyone else.

                        We have scientific literature that proves opposite of what you are saying...So either that stuff is wrong, you are wrong, or you are both right and it is different for each individual.

                        Comment

                        • JulioGP
                          Senior Member
                          • Feb 2013
                          • 293

                          I agree with you.

                          I concluded that the literature does not work for everyone. Have to take the test and do blood tests. You can not just rely on the literature.

                          Comment

                          • mowingdown
                            Junior Member
                            • Aug 2015
                            • 17

                            Just browsing old threads. Is this still working for you?

                            Comment

                            • Sam01
                              Junior Member
                              • Oct 2017
                              • 4

                              Loomings an update bro?

                              Comment

                              • Pike1
                                Junior Member
                                • Jan 2018
                                • 1

                                Hello everyone

                                It's my first post on this forum, I have read this discussion with interest as I contemplated taking finasteride for the last couple of years as I was advised to do so by a well known HairLoss centre here in UK, after reading tons of information on the net I decided to start taking a dose of 0.5mg daily on the 21st Dec 2017, on the very same day I experienced a mild pain in the nuts which on and off persisted on a daily basis, after 3/4 days I noticed my morning erections stopped and I can sincerely say that after 7/8 days I had serious difficulties to have sex with my wife. I am not sure if I fall in the 1 or 2% stats but surely this was enough to scare the hell out of me and stopped this stuff last week. My plan is to go back to a dermatologist and start from basics again (blood tests eccetera..) and see where things are wrong .

                                I find incredible that after 20 years there are still arguments on the effectiveness and the correct usage of this drug. Don't you all agree?

                                On the other hand I am also very interested how did it work out for Loomings.....

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