RU is working wonders on Hairloss Help

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  • Troy
    replied
    Originally posted by Amino
    Hi Gents,

    I'm finding the 5% solution from MPB too strong for me (i was also very sensitive to Dut).

    Rather than waste it, anyone have any thoughts on dilluting it to the equivilent of 1% solution? Can I just mix it with something? Any thoughts?

    Thanks.
    This question got me thinking...

    So in the patents of K&B solution, the solutions of 5% and 2% are:

    Kraemer & Bohn’s 5% RU58841 solution (KB5)
    - 27% Demineralized water
    - 63% Ethanol (96%)
    - 2.5% BASF Cremophor RH 410
    - 2.5% BASF Luviquat FC 550
    - 5% RU58841
    Kraemer & Bohn’s 2% RU58841 solution (KB2)
    - 54% Demineralized water
    - 40% Ethanol (96%)
    - 2% BASF Cremophor RH 410
    - 2% BASF Luviquat FC 550
    - 2% RU58841
    So let's say we want to transform your 5% into 2%, and what you can easily get is distilled water and ethanol.

    The ratios change mainly in these two.

    60ml 5% solution contain 27% water (something like 16.20 ml) and 63% ethanol (something like 37.80 ml)

    You have to start with yours 60ml, let's assume you'll make the double of this - 120 ml - wich will get you a little more than 2% of RU concentration, and we can try to base our math in the Kraemer & Bohn’s 2% RU58841 solution.

    120ml 2% solution contain 54% water (something like 64.80 ml) and 40% ethanol (something like 48.00 ml)

    Based on the diferential of water between 5% (60ml) and 2% (120ml) (16.20ml / 64.80ml) I guess you can try to add something like 48ml of distilled water.

    Based on the diferential of ethanol between 5% (60ml) and 2% (120ml) (37.80ml / 48.00ml) I guess you can try to add something like 12ml of ethanol (96%).


    I don't know if this will work...I would appreciate also someone's thoughts on this...


    Resuming: Add 48ml of distilled water and 12ml ethanol (96%), you will get 120ml with a much more diluted solution.

    Leave a comment:


  • Jairus
    replied
    Originally posted by Troy
    You apply the cream directly to the scalp...No need to dissolve it in anything!

    If you have shaved/buzzed hair it's good to apply...I have a bit long hair, so it's a nightmare, unless you only apply to the hairline.
    Cheers Troy

    Do u use it yourself? In terms of applications would it be once a day?

    Is the cream stronger than the liquid RU?

    I know its a topical anti androgen, but since it seems to penetrate the scalp more, could there be sides?

    Leave a comment:


  • Troy
    replied
    Originally posted by Jazz1
    How much is PSI and how is it mixed or used etc?
    The concentrations used in the trials were 0.5%, 1%, 2% and i think they even used 5%!

    The vehicle is very simple: ethanol, PG, distilled water

    Leave a comment:


  • Troy
    replied
    Originally posted by Jairus
    I see on mpbtreatments that they have RU in a cream. Is this just applied normally out of the tin? Any dissolving needed? Seems to be easier to apply topically.

    Can anyone comment on this?
    You apply the cream directly to the scalp...No need to dissolve it in anything!

    If you have shaved/buzzed hair it's good to apply...I have a bit long hair, so it's a nightmare, unless you only apply to the hairline.

    Leave a comment:


  • Jairus
    replied
    I see on mpbtreatments that they have RU in a cream. Is this just applied normally out of the tin? Any dissolving needed? Seems to be easier to apply topically.

    Can anyone comment on this?

    Leave a comment:


  • clandestine
    replied
    Originally posted by lilpauly
    PSI IS NOW available!
    For 400$/g

    Leave a comment:


  • Jazz1
    replied
    How much is PSI and how is it mixed or used etc?

    Leave a comment:


  • Troy
    replied
    I answered this a few days ago in this thread...

    Not an anti androgen and much more than a growth stimulant.

    It works on bone morphogenic protein (BMP). As stated, not only does it increase BMP2 (hair growth) and decrease BMP4 (hair loss) but it also inhibits the way the immune system attacks the hair follicle during MPB (anti-inflammatory properties) and inhibits cell apotosis (cell death) in the follicle. Aside from inhibiting proteasomal activity it also decreases the activity of the transcription factor NF-.kappa.B.
    The most exciting part about this treatment is that it works in a totally unique fashion. “Topical administration of OSH101 strongly stimulates dormant hair follicles, increases hair follicle thickness, and overall hair growth” So it’s not going to just affect existing hair like Minox does, it affects DORMANT follicles as well. In the trials, there was a 5% increase in total hair count in JUST 28 days of treatment

    Leave a comment:


  • Jazz1
    replied
    Originally posted by lilpauly
    PSI IS NOW available!
    What is this stuff bro?

    Leave a comment:


  • lilpauly
    replied
    PSI IS NOW available!

    Leave a comment:


  • Amino
    replied
    Dilute 5% Solution

    Hi Gents,

    I'm finding the 5% solution from MPB too strong for me (i was also very sensitive to Dut).

    Rather than waste it, anyone have any thoughts on dilluting it to the equivilent of 1% solution? Can I just mix it with something? Any thoughts?

    Thanks.

    Leave a comment:


  • Troy
    replied
    Originally posted by dex89
    ohhh, in that case, were do I sign up?
    PM someone involved in the group buy over at HLH - Troy, BaldinLikeBaldwin or Marklc2004...

    Leave a comment:


  • dex89
    replied
    Originally posted by Troy
    Exactly



    You just throw RU in and it should dissolve.
    ohhh, in that case, were do I sign up?

    Leave a comment:


  • Troy
    replied
    Originally posted by Jazz1
    KB is already mixed solution you just throw in RU.
    Exactly

    Kraemer & Bohn’s 5% RU58841 solution (KB5)
    - 27% Demineralized water
    - 63% Ethanol (96%)
    - 2.5% BASF Cremophor RH 410
    - 2.5% BASF Luviquat FC 550
    - 5% RU58841
    You just throw RU in and it should dissolve.

    Leave a comment:


  • Jazz1
    replied
    Originally posted by dex89
    hmmm interesting, but what liquid form do you mix with RU and K&B?

    I'm interested in joining this group buy.
    KB is already mixed solution you just throw in RU.

    Leave a comment:

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