Inconclusive rant about finasteride, DHT reduction and ways to control it.

[Aston]

Aston; how are you fairing with the modified dosage?

My progression:

at start: aged 22, good libido, some acne (very oily skin), slow hair loss (NW2), very deep sleep

Day1: 0,3125mg (1st dose)
Day2: sleep issues (sleeping but waking up horribly tired)
Day3: sleep issues, Skin sebum feels entirely gone, previous acne healing
Day4: 0,3125mg (2st dose), sleep issues
Day5: sleep issues
Day6: sleep issues, acne gone, excess skin sebum gone
Day7: sleep issues get progressively better
---decided to wait one week before next dose---
Day14: 0,150mg
Day15: restless, but good sleep, acne still gone
Day16: good sleep (not as deep as before fin)
Day17: 0,150mg, good sleep
Day18: -today-

The lack of oil on my skin and scalp makes me think my DHT was kept fairly low despite the low doses and the 1 week pause. Will return to 0,3125mg at the next dose. No effect whatsoever on libido or anything else for now, but it's early for that, apparently.

[gutted]

maybe they had low DHT and low T to begin with.... finasteride has side effects just like any other drug. The numbers are correct. If you got side effects, you are part of those 3%. Deal with it

hormone levels fluctuate between individuals.
so i dont think this matters at all, if they had low tesosterone/dht levels then they would have had equally/balanced sensitive adnrogen receptors to maintain the status quo i.e homeostasis.

if they had highly sensitive andorgen receptors they probably would have a low dht/testosterone profile but this does not mean they would have erectile dysfunction based on their natrual low test/dht profile, the body would maintain the balance.

the key with propecia is the dosage, you need to find the right balance for yourself. the recomended dosage by merck is overkill and it is this, they need to revise.


there are plenty of people suffering sides from propecia dn there probably an equal number of people probably not suffering sides...right now, as it stands going on propecia is a gamble.

[chrisis]

Thanks Aston. You get it!

[Aston]

The numbers are correct for the tested population and represent an average, which is subject to errors in application.

Also, balding men in their twenties reportedly all have low T and high DHT. Either their 5a reductase enzyme is too active (current theory) or their SBHG production is impaired.

Unfortunately we do not posses enough data to assert anything and we should therefore stay open to the possibility.

[clandestine]

There are many theories which could validate the condition called "Post Finasteride Syndrome" and we can't logically exclude the possibility that certain pockets of population outside of the control groups in studies are vulnerable to it for one reason or another.

The many men who have placed their hopes on the effectiveness of finasteride (such as myself) will clearly always fight theirs fears and whoever fuels them, but whatever the truth is, many men feel finasteride has caused permanent damage to their health. All we can do is look together into the mechanics of such claims and compare data, for everyone's sake. Unfortunately medical science is still far from perfection, as are pharmaceuticals. Whether you like it or not, the ultimate "clinical trial" is the consumer market.

Arguing with partial knowledge for the sake of personal fears or unproven theories is futile and will only sour healthy discussion.

Aston; how are you fairing with the modified dosage?

[2020]

There are many theories which could validate the condition called "Post Finasteride Syndrome" and we can't logically exclude the possibility that certain pockets of population outside of the control groups in studies are vulnerable to it for one reason or another.

maybe they had low DHT and low T to begin with.... finasteride has side effects just like any other drug. The numbers are correct. If you got side effects, you are part of those 3%. Deal with it

[Aston]

There are many theories which could validate the condition called "Post Finasteride Syndrome" and we can't logically exclude the possibility that certain pockets of population outside of the control groups in studies are vulnerable to it for one reason or another.

The many men who have placed their hopes on the effectiveness of finasteride (such as myself) will clearly always fight theirs fears and whoever fuels them, but whatever the truth is, many men feel finasteride has caused permanent damage to their health. All we can do is look together into the mechanics of such claims and compare data, for everyone's sake. Unfortunately medical science is still far from perfection, as are pharmaceuticals. Whether you like it or not, the ultimate "clinical trial" is the consumer market.

Arguing with partial knowledge for the sake of personal fears or unproven theories is futile and will only sour healthy discussion.

[2020]

Wow I feel like I'm arguing with a wall.

Your lack of ability to comprehend my point just stumps me. This is why I eventually ignore you.

what?

Men with more advanced balding patterns will react differently to drugs designed to inhibit the hormones that caused the balding. It's very basic logic.

^ This is false.

Care to try for another theory?

[chrisis]

Wow I feel like I'm arguing with a wall.

Your lack of ability to comprehend my point just stumps me. This is why I eventually ignore you.

[2020]

Wow someone's getting worked up...

I have yet to see a study that proves Propecia is safe for men with receded hairlines only or a study that fairly represents such men.

do I need to dig up those studies again?? Even on the official study, THEY HAD A SURVEY where they asked the subjects if they had an improvement on their hairline.
OBVIOUSLY those people had hairline loss as well, it's just that the study focused more on the crown because they knew that that's where propecia would be most effective....

Men with more advanced balding patterns will react differently to drugs designed to inhibit the hormones that caused the balding. It's very basic logic.

right, so ALL OF THOSE STUDIES just happened to pick up super humans with super hormone profiles and that's how they were able to conduct studies with minimal side effects.... you're not special. Balding pattern is genetic. DHT is not even the cause of hairloss ffs you fool

[chrisis]

Wow someone's getting worked up...

I have yet to see a study that proves Propecia is safe for men with receded hairlines only or a study that fairly represents such men.

Men with more advanced balding patterns will react differently to drugs designed to inhibit the hormones that caused the balding. It's very basic logic.

[2020]

You can't say the side effects are on a par with aspirin and Clarityn when the Propecia studies are flawed, as I've pointed out again and again.

no you ****ing didn't omfgg do you have amnesia? Your "different hormone profiles" theory was a bs.... you hormones were either ****ed up from the beginning(pre-existing condition) or you're just one of those few who DO get side effects.
It's been TWENTY YEARS! Study after study CONFIRMS their original study results. WHY CAN'T YOU GET THIS THROUGH YOUR HEAD!!! It's not us - IT'S YOU!!!

[chrisis]

To be fair there are people out there who say they have sexual issues after taking Claritin. Also, aspirin is an over the counter too but it causes plenty of deaths every year. Propecia is pretty much right on par when it comes to side effects compared to other drugs.

You can't say the side effects are on a par with aspirin and Clarityn when the Propecia studies are flawed, as I've pointed out again and again.

[WashedOut]

Yeah I'll keep it up for now. Probably got about a month's supply so we'll see how I am at the end of my batch.

I'm floored at the suggestion that it's a gamble for me to take a common household non-prescription medicine, that has side effects limited to a bit of drowsiness, while a drug that can potentially devastate your sexual health is defended to the death...

I usually get a bit of hayfever this time of year anyway, so taking Clarityn is not unusual for me.

If this doesn't resolve my problem however, I will go to a doctor and get some tests run.

To be fair there are people out there who say they have sexual issues after taking Claritin. Also, aspirin is an over the counter too but it causes plenty of deaths every year. Propecia is pretty much right on par when it comes to side effects compared to other drugs.

[chrisis]

I would suggest giving it a full month to deal with cycles before really coming to any conclusion. It makes sense that one would get excited when you notice an initial improvement, but it is not uncommon to see one treatment work for a little bit and then stop for unknown reasons.

Yeah I'll keep it up for now. Probably got about a month's supply so we'll see how I am at the end of my batch.

I'm floored at the suggestion that it's a gamble for me to take a common household non-prescription medicine, that has side effects limited to a bit of drowsiness, while a drug that can potentially devastate your sexual health is defended to the death...

I usually get a bit of hayfever this time of year anyway, so taking Clarityn is not unusual for me.

If this doesn't resolve my problem however, I will go to a doctor and get some tests run.