Is minoxidil causing wrinkles?

[VictimOfDHT]

Ok. Don't take it then. I don't know why people keep coming here and telling us this drug does this and this one does that. Some people here have nothing better to do but keep telling us how bad Finasteride is and how it's the most dangerous drug ever made.... The same thing is going on with Minoxidil. Here and on other forums people keep telling us Minoxidil makes your face look like shit and makes you look older.... Ok. DON"T ****ING USE MINOXIDIL OR FIN. It's not like we're kids here. We know what the hell we're doing and all of us -I'm assuming- can make our own decisions. Why don't people get it? Talk about a topic that hasn't been discussed like 10 million times.

And like I said before, I'd rather look 70 with hair than look young with no hair (bald), that is IF you can ever look young when you have a balding head.

[TheDude]

This study suggests that minoxidil does in fact decrease collagen:

"Collagen synthesis
Two groups have studied the effect of minoxidil on collagen synthesis. Murad and Pinnell48 showed that minoxidil suppressed activity of the enzyme lysyl hydroxylase in human skin fibroblast cultures at concentrations down to 25 lmol L)1, leading to pro- duction of a collagen deficient in hydroxylysine.49 This appeared to be specific for lysyl hydroxylase as the activity of prolyl hydroxylase, which shares the same substrates and cofactors as lysyl hydroxylase, wasunaffected. Minoxidil (0Æ5 mmol L)1) also suppressed collagen synthesis by rat vibrissae dermal papilla cells, both in monolayer cultures and in cells grown in collagen gels.50 The concentrations of minoxidil used in these studies were quite high and the relevance of the results to hair growth is unknown".

http://www.dslaboratories.co.uk/spectralDNC-L/BJD150MinoxidilMech.PDF

[TheDude]

If Minoxidil caused premature againg, women would never touch the stuff

Funny you mention that because this is exactly what this women's skin site is worried about..

http://www.savvyskin.com/does-rogaine-cause-wrinkles

Im not advocating whether it does or doesn't, i too have been on it for the past 4 years, im just worried that its causing a decrease in the collagen in my face..

Do people on this stuff notice this kind of skin deterioration or is it another "how can you prove its minoxidil or just age"

[john2399]

Yeah i don't believe this too. We have enough to worry about, we don't need to add this myth to our problems. Minoxidil works and the maybe the wrinkles are coming from all the worrying from hairloss!!

[Tracy C]

Is this stuff prematurely aging us..

This nonsense again? I've been using Minxodil for over four years now. If Minoxidil caused premature againg, women would never touch the stuff. More women need to use Minoxidil than you realize. It hasn't aged me one tiny bit. I look more than ten years younger than I actually am.

I swear there is someone out there trying to scare people away from using legitimate treatments for hereditary hair loss.

[chrisis]

If true then how annoying.

Finasteride breaks my dick. Minoxidil breaks my face.

I'm not religious, but it's like a big **** you from the guy upstairs.

[TheDude]

Is this stuff prematurely aging us..

Im worried about this since im still young but am noticing what it seems like premature wrinkles when compared to my friends faces..

Apparently minoxidil depletes or decreases the collagen in your skin and not only your face but everywhere since it travels through the blood stream.

Here's a site where people are saying just that..

http://www.publichealthforums.com/h-33-minoxidil.html