Avodart success or failure?

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  • ThinFast
    Senior Member
    • Apr 2010
    • 152

    #16
    CVAZBAR, my goal has been to retain as much as possible until Histogen, Acell, or something becomes a reality. I still am taking .5mg/day of Avodart in hopes that I'm at least slowing it down. I really don't think I am though based on how fast it is miniaturizing. I've seen a strand of my hair that is no more than 1.5"-2" long and it'll start off nice and thick, halfway down it becomes noticeably thinner until it gets down to the white bulb at the end where it almost invisible. I have tried laser at a clinic and had a PRP with protein matrix session down at Greco's in Florida about 5 months ago. My hair is hell bent on falling out. I will probably stop the avodart since it seems pointless and switch over to trx2. It may be just as ineffective, but it's about $35 USD cheaper a month than avodart.

    I'm not a doctor, so I may not be 100% explaining this correctly, but according to a conversation I had with Dr. Bauman back earlier in 2010 regarding my CAG score and androgen receptors, every person has a different number of androgen receptors for each hair follicle. Receptors are basically the things that DHT "bonds" to if you will. They are the other part of the DHT equation that cause miniaturization. When you take a DHT inhibitor, you're decreasing the amount of DHT in your body that can bond to these receptor sites. If you've read through enough of different poster's treatment regimens on here, I'm sure you've heard of something referred to as "Spiro". Spironolactone has a few functions, but mainly it used to block the androgen receptor sites from bonding with circulating DHT. The more androgen receptors per follicle that a person has, the more dht can bond to that follicle and miniaturize the hair. So even though I've reduced the amount of dht in my blood, I still potentially have a shit ton of androgen receptors per hair follicle for the small amount of dht to bond to, which still miniaturizes my hair. I've tried Spiro too with all of the other treatments, although I was only it for about 3 months, but it also didn't seem to help me. As you correctly said before, I'm pretty much ****ed.

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    • CVAZBAR
      Senior Member
      • Dec 2010
      • 443

      #17
      Originally posted by ThinFast
      CVAZBAR, my goal has been to retain as much as possible until Histogen, Acell, or something becomes a reality. I still am taking .5mg/day of Avodart in hopes that I'm at least slowing it down. I really don't think I am though based on how fast it is miniaturizing. I've seen a strand of my hair that is no more than 1.5"-2" long and it'll start off nice and thick, halfway down it becomes noticeably thinner until it gets down to the white bulb at the end where it almost invisible. I have tried laser at a clinic and had a PRP with protein matrix session down at Greco's in Florida about 5 months ago. My hair is hell bent on falling out. I will probably stop the avodart since it seems pointless and switch over to trx2. It may be just as ineffective, but it's about $35 USD cheaper a month than avodart.

      I'm not a doctor, so I may not be 100% explaining this correctly, but according to a conversation I had with Dr. Bauman back earlier in 2010 regarding my CAG score and androgen receptors, every person has a different number of androgen receptors for each hair follicle. Receptors are basically the things that DHT "bonds" to if you will. They are the other part of the DHT equation that cause miniaturization. When you take a DHT inhibitor, you're decreasing the amount of DHT in your body that can bond to these receptor sites. If you've read through enough of different poster's treatment regimens on here, I'm sure you've heard of something referred to as "Spiro". Spironolactone has a few functions, but mainly it used to block the androgen receptor sites from bonding with circulating DHT. The more androgen receptors per follicle that a person has, the more dht can bond to that follicle and miniaturize the hair. So even though I've reduced the amount of dht in my blood, I still potentially have a shit ton of androgen receptors per hair follicle for the small amount of dht to bond to, which still miniaturizes my hair. I've tried Spiro too with all of the other treatments, although I was only it for about 3 months, but it also didn't seem to help me. As you correctly said before, I'm pretty much ****ed.
      Well i might be having the same problem because Propecia did nothing for me in 6 months and my hair continues to fall out. Did the Avodart help the hair shedding at least? So do you think i should try that Spiro for the androgen receptors, along with the avodart? This shit is ridiculous. I wonder if there could be something to reduce the androgen receptors significantly. I know it sounds stupid because im not a Doctor but if you potentially have more than the average person, i don't know how it would affect you destroying some of those bastards. Maybe you can talk to a doctor about this? It just seems unrealistic that something like that would keep the medicine from working. This makes me think negative about the rest of the medications that will potentially come out. I mean if this shit don't work for us, than how will trx2, Histogen, Aderans of Acell help us?? It's frustrating. Hey Bro at least you have you're girl and I'm sure if she has been with you through all this, you don't have to worry about her at least. i personally don't think i look good bald but i guarantee you that if i was satisfied with how I looked bald, i would not give a shit about going bald. Plus where i come from you see BALD guys everywhere, even when they are not losing their hair haha. Don't worry BRo. Keep Me updated on the TRX2 since you are going to try it already. I will probably have to try it myself sooner or later. Do you know if Spencer talked about this in his show already?

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      • ThinFast
        Senior Member
        • Apr 2010
        • 152

        #18
        CVAZBAR, the funny thing about my hair shedding is that it was pretty much constant whether I was taking propecia, avodart, or using some sort of minoxidil formula. It never changed. I don't think I necessarily had "sheds" but I could count about 70 hairs that would accumulate when I would shower. The main thing was just the amount of miniaturization that was taking place on each follicle. I was told by a doctor that miniaturization is something that happens over cycles of each hair follicle and that it's not something you can see on an individual hair. I'd really like to know then why every single one of my hairs starts out really thick and gets much thinner almost immediately.

        I'm not sure you can destroy the androgen receptors. I believe it's one of those "it is what it is" deals. As far as the effectiveness of other meds vs. the status quo dht inhibitors like propecia and avodart, I'm actually encouraged. The normal stuff didn't work and the fact that today the science is attacking this problem from a different angle and at more of a cellular level has my hopes up.

        My girl is somewhat in denial about my hairloss. She is really the only reason I haven't shaved my head yet cause she says she will hate the way it looks. So, it's not quite as peachy there as it could be. I've accepted what's going on and everytime I show her what hair loss is, she claims she can't see it. I'm not sure if it's to not hurt my feelings or what, but I've accepted it and she needs to as well. I did shave my head once in highschool and ironically got more girls then than when I had a full head of hair. Still, you could obviously see the shadow of where I would have hair on my head, unlike the baby smooth skin a truly bald guy will have on his dome.

        I didn't get a chance to tune in for all of Spencer's show this past Sunday evening, I caught the last hour or so and they were talking about religion for all of it. It obviously wasn't informative in regards to hairloss and I didn't particularly care for it, but I do understand the format of his show and you can't just talk about hair loss all of the time. Most of the time it is very informative and to me it sounds like a bunch of guys just chilling, having a drink at a bar and shooting the shit which I like. I haven't ordered trx2 yet, probably will bite that bullet this evening. I'm just holding out a little longer to do a little more research on it. Good luck man!

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