Dut and Ketoconazole interaction

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  • BaldingHelpMe
    Member
    • Sep 2015
    • 90

    #1

    Dut and Ketoconazole interaction

    Over here, it lists drugs that will affect Avodart:

    https://www.drugs.com/avodart.html

    and here, it states: "Ketoconazole may increase the blood levels of dutasteride"

    https://www.drugs.com/drug-interacti...-1412-837.html

    So, using keto will actually increase the effectiveness of dutasteride?
  • BaldingHelpMe
    Member
    • Sep 2015
    • 90

    #2
    Upon further reading, dutasteride is metabolized extensively by CYP3A4 enzyme, whereas Ketoconazole is a strong CYP3A4 inhibitor, and they do have drug interaction.

    So, better avoid using ketoconazole while on dut?

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