Dutasteride + NR-10 + Finasteride (All topical)

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  • doke
    replied
    Originally posted by Conpecia
    i hate it when guys just abandon threads without the simple courtesy of saying "it didn't work" or "i gave up on it." i've seen recent pics of incredible results from a turkish guy who claims to have mixed 10 pills of avodart into minox for 6 months. regrew all of his hair. a google search of topical dut with minox led me to this thread, where apparently brazilians were doing this with success. of course there are no pics and the threadstarter bailed months ago. who knows if this works or not? why waste our time if you're not going to follow up??

    if anybody has heard anything about this treatment PLEASE let us know...
    Hi have you a link to his pics and did he mix 10 avodart into 60mls of minox and also which brand of minox did he use?

    Leave a comment:


  • gDavid
    replied
    Has anyone else tried this regimen? I think I might try this.

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  • Conpecia
    replied
    i hate it when guys just abandon threads without the simple courtesy of saying "it didn't work" or "i gave up on it." i've seen recent pics of incredible results from a turkish guy who claims to have mixed 10 pills of avodart into minox for 6 months. regrew all of his hair. a google search of topical dut with minox led me to this thread, where apparently brazilians were doing this with success. of course there are no pics and the threadstarter bailed months ago. who knows if this works or not? why waste our time if you're not going to follow up??

    if anybody has heard anything about this treatment PLEASE let us know...

    Leave a comment:


  • Plan C
    replied
    Can somebody explain how one purchases Polaris products please.

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  • adarse
    replied
    whos the maker of generic proscar?

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  • Tarikko
    replied
    Originally posted by Jazz1
    Bro guess what I bought aswell? NR-11 il take pictures tommorow I'm not trying it yet as I want to use Susan's products, I might add NR-11 to my regime .
    Jazz bro, the NR11 has the same components as what you are ordering from Susan, no?

    Leave a comment:


  • StayThick
    replied
    I might try this.

    I'm in the camp that have suffered mightily with FIN sides when taken orally. I am really curious if this would cause similar sides as well.

    However; I'm still confused on how many 0.5mg tablets I must mix into a bottle of Kirkland minox. I don't want to use many (overkill) since I suffered with very bad sides with FIN. What is the recommended dose for someone wanting to ease their way into this?

    5 pills, 10 pills? What would that equate to mg wise if assumed it was oral? Trying to figure out the math here...

    Leave a comment:


  • Jazz1
    replied
    Originally posted by Tarikko
    Hey Julio,

    Could you provide us with an update?
    Bro guess what I bought aswell? NR-11 il take pictures tommorow I'm not trying it yet as I want to use Susan's products, I might add NR-11 to my regime .

    Leave a comment:


  • Tarikko
    replied
    Hey Julio,

    Could you provide us with an update?

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  • burtandernie
    replied
    I just to remind people with short memories that merk actually gave men the choice of topical or oral finasteride back before propecia and men choose oral. So all the sides and all that are our choice we picked the convenience of the oral pill over the safer topical version. Why 20 years later there are still no actual topical DHT inhibitors approved for MPB though I have no idea.

    Leave a comment:


  • Jazz1
    replied
    Bump, is the NR-10 any good stuff?

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  • angmar
    replied
    Originally posted by JulioGP
    Guys,

    I'm starting a new treatment protocol . As already suffered the side with oral finasteride , now all topic. We're checking here in Brazil there are several people with excellent feedback regarding topical dutasteride .

    The process is quite simple . Mix the contents of the capsules of dutasteride to some common Minoxidil ( in my case , I mix with Polaris NR - 10 ) . There are many people who are putting in Kirkland , with great results .

    Here , we are mixing 20 capsules ( 0.5 mg each) for each 60ml Minoxidil . This gives a concentration of 10 mg of dutasteride for each 60ml , or a concentration of 0.016 % in topical solution .

    Some say it is the best treatment we have done and achieved easily and in short time , jumping from a NW3 (vertex ) for NW2 and continue to improve. Are users who are already in this fight against baldness for years . Most had severe side effects with oral finasteride , however, when using topical dutasteride , reported no side effects .

    It would therefore like to share with you . Under the portfolio of my new treatment .



    Results how?
    Do you still use?
    (Are there side effects?)
    I am writing from Turkey. What do you suggest?

    Leave a comment:


  • angmar
    replied
    Hi, I want to try.
    Is there a danger? Are there side effects?

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  • thechamp
    replied
    I found some info

    I'm not sure if anyone knows
    At least 2 and at most 10 per month, if you want your scalp to get the same DHT conentration as 2.5mg orally would give. My guess is 4 is optimal. Most people who tried did 8 or 10 and got great results. Lower doses cost less and have less systemic effect. I advise applying it at least twice per day, since I don't know how long it stays in the scalp before getting rinsed away by the blood.

    You will NOT overdose on 10, or even 30, unless your scalp aborbs 100% compared to your intestine's 60%, which would mean you get the systemic effect of taking 0.56 to 1.66 pills per day oral, which is 0.28mg to 0.83mg per day. I suspect only 1/3 will get absorbed, and at 4 pills a month, your body gets ((4/(3*30))/0.6)*.5mg = 0.037mg/day, which is less than the amount that is equivalent to Propecia (0.1mg). And the much of amount the body gets will already be used because it took AR5 from the scalp with it. However, your scalp will get 200 times this much based on volue, if the Dut stays there long enough, which means 7.4mg per day. If the scalp gets saturated with Dut, no more will be absorbed until some leaves. I suspect the blood will take a lot away, but I don't know how much or fast, and therefore can't give an ideal dose.

    Math:
    Any transplant site will tell you the MPB are is 200cm2. Lets include the surounding horse shoe and say 400cm2. Laser hair removal sights say that most follicles are 2-5mm deep, but that scalp hair is 7mm deep. So assume the scalp is 1cm deep. That is 400cm3. Assume the human body is 80kg and has the density of water, 1g/cm3 which is 1kg/1000cm3.
    400cm3/80,000cm3 = 1/200. Concentration = amount of Dut/volume. The intestine absorbs 60% of Dut in capsules. I read that testosterone patches, which have 12g of testosterone in a past, only get 4g through the skin, and Dut is bigger than testosterone, but absorption ratios are much higher at low concentrations and especially in liquids instead of pastes.
    Pictures below:
    Dutasteride blocks both Type 1 and Type 2 5-alpha reductase, cutting serum DHT by up to 94%. The mechanism step by step, in BPH, hair loss and the PK data.


    http://www.bdg.co.nz/reference-standard ... 925.0.html
    I use 1/3 absorption as a ball park figure. It could be 95% or 30%, but an underestimate makes sure you get enough. Your goal is to load what 2.5mg orally would do to the scalp. I assume that DHT concentrations in serum and scalp are the same, but I could be way off on that. The prostate probably takes most of it was it since it is big and near the gut and has type II AR, which Dut likes. The scalp is probably mostly type I. Good news is most topicals come down the follicle like a highway, while also slowly entering directly through the skin. This is the only reason to keep your pores unplugged, so the smallest follicles that need it most can get some. Anyway, take the 1/3 and plug use it and you get the math expressions I have above. 7.4mg per day is very high, but since the blood probably rinses Dut away as it comes in, concentrations probably don't get that high. I'd use a small dose more often if you don't mind applying it, like 2-3 capsules per bottle and 1.5 bottles per month, three times per day. You probably need more than 1mL to cover your 200cm2 (and let the rest diffuse to your horse shoe. So maybe 1-2 capsules per bottle of Minoxidil 5% diluted with 70% issoproply, 2 mL per application, 3 times per day.

    The people who applied 1mL twice per day with 8-10 capsules in 1 bottle had great results. But remember that what goes in, unless sweated out, must go to the body, and can give you the full does with side effects, just with your hair fortunately getting first shot instead of the prostate skimming it all off the top.

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  • thechamp
    replied
    Calling Julio you think it would be worth putting 3 to 4 fur tablets in minoxdill has any body on the Brazil forum put less than 20 tablets in 60 ml of minoxdil.

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