Dutasteride + NR-10 + Finasteride (All topical)

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  • thechamp
    replied
    20 capsules in 60 ml minoxdil sounds a liitle bit too much, Julio what's a good way to try dut topically you think I could try shampoo or just take the capsules and run them on my head , maybe I can avoid weight gain and get results ??

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  • JulioGP
    replied
    When using oral finasteride, which is either to reduce the DHT in the scalp. When applying Finasteride or Dutasteride scalp, you have a DIRECT site reaction, doing the same process with the 5AR.

    This has been proven recently at the 7th World Congress on the subject. Although there is some systemic absorption can probably be that the metabolism of finasteride through skin absorption takes place in a different form of oral and in turn does not jeopardize neurosteroids that are identified as the main problems related to side effects, mainly irreversible.

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  • frankzukini
    replied
    Well, testosterone is also locally metabolized into DHT by the enzyme, but you're essentially right. Topically using an androgen receptor antagonist (RU58841) makes so much more sense.

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  • kmit028
    replied
    Default Fin is a type II 5α-reductase inhibitor!

    Fin is a type II 5α-reductase inhibitor. 5α-reductase is an enzyme that converts testosterone to dihydrotestosterone (DHT).

    So FIN does not react with or affect DHT directly. It only inhibits the chemical (5α-reductase) that creates DHT from Testosterone.

    So if you have FIN in your scalp but not in your blood, wouldnt it be useless as the enzyme 5α-reductase will still make DHT???

    Could someone confirm this as not sure my science is quite right

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  • Jcm800
    replied
    Originally posted by Jazz1
    Iron dragon sell liquid Dut.
    Thanks Julio.

    Where are iron dragon based, Japan?!

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  • Jazz1
    replied
    Originally posted by JulioGP
    Sorry about the intrusion.

    I found here:


    Not in the UK, but without prescription. But they don“t send to Brazil.
    Iron dragon sell liquid Dut.

    Leave a comment:


  • JulioGP
    replied
    Sorry about the intrusion.

    I found here:


    Not in the UK, but without prescription. But they don´t send to Brazil.

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  • Jcm800
    replied
    Hey Doke - are you aware of anywhere legit in the UK that I could get some dutas without a prescription? Not likely I guess?!

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  • JulioGP
    replied
    Doke,

    The best result I've had so far with some topical treatment was the time I used the Spectral DNC-L, but the formula has changed and found that the product has lost effectiveness. I went from NW3 to NW2 in a matter of 3 months.

    Currently I am using the NR-10 as the transport vehicle to add dutasteride, since the NR-10 contains Finasteride in its formula and already has the required to transport the same vehicle, so I take the same ingredients for transport the Dutarterida. The Genhair I use only to increase the % of Finasteride.

    Not sure about that combo can bring more results, use only to enhance the treatment and enjoy the vehicles needed to carry dutasteride I'm entering the bottle.

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  • doke
    replied
    Originally posted by JulioGP
    Yes, I will do blood tests every 2 months.

    Interestingly, some users in Brazil are having the results simply by opening the capsules Avodart and passing liquid directly on the scalp, with no need to mix any other components for the transportation of the product.
    Just do a little local ticket and nothing more.

    These users had used oral finasteride and had serious side effects. They had also tried all other topics based Minixidil etc., as Kirkland, Spectral DNC-L, DNC, Polaris, Lipogaine and etc. Anyway, just wanted to pass on to the staff what is working, adding that in their treatments, especially if they are not giving the expected results, give it a try since whoever is doing is having results. I'll be back in a few months to give some feedback.

    Give it a try.
    hi j was you getting results before using topical dutas or are you getting better regrowth with the combo?

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  • JulioGP
    replied
    Yes, I will do blood tests every 2 months.

    Interestingly, some users in Brazil are having the results simply by opening the capsules Avodart and passing liquid directly on the scalp, with no need to mix any other components for the transportation of the product.
    Just do a little local ticket and nothing more.

    These users had used oral finasteride and had serious side effects. They had also tried all other topics based Minixidil etc., as Kirkland, Spectral DNC-L, DNC, Polaris, Lipogaine and etc. Anyway, just wanted to pass on to the staff what is working, adding that in their treatments, especially if they are not giving the expected results, give it a try since whoever is doing is having results. I'll be back in a few months to give some feedback.

    Give it a try.

    Leave a comment:


  • Dan26
    replied
    Julio do you plan still to test your blood while you are on this new protocol?

    I think maybe it could be effective in a special vehicle or with mesotherapy but in a standard vehicle it wont have any greater local activity etc

    Leave a comment:


  • JulioGP
    replied
    If someone did before, did not know.

    I'm just reporting that some people have done it here and has worked. The first report is from December 23, 2011.

    Already a long time and I think if there were systemic absorption, they would have said, but did not continue using. And users who have had serious side effects with the use of oral finasteride problems.

    I would not put so many certainties in these statements, I prefer to believe the people who are using and continue reporting today.

    For those interested, here is the information (only in Portuguese).


    I do not want anyone here believe in something, each believe what they like. Just wanted to bring the information.

    Be well.

    Leave a comment:


  • SOTF
    replied
    Originally posted by frankzukini
    Do you have anything to back this statement? Realistically, it could exhibit antiandrogenic activity exclusively in the scalp, by being metabolised before going systemic, much like CB does.
    Except that won't happen. Both will go systemic and give you the exact same benefits and pitfalls as if you took them orally.

    Do I need to post a "Man Lands on the Moon" headline?

    Where have some of you been? Do you truly believe people weren't putting both fin and dut on their scalps since day one?

    People are "getting results" from applying these drugs topically because they are GOING SYSTEMIC.

    We as a community have exhausted every other option right now so it is time to recycle old, tired ideas as if the people doing this are new-age pioneers. Come on!

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  • frankzukini
    replied
    Originally posted by Dan26
    If it works it will be because it's lowering your blood DHT
    Do you have anything to back this statement? Realistically, it could exhibit antiandrogenic activity exclusively in the scalp, by being metabolised before going systemic, much like CB does.

    Leave a comment:

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