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Could Histogen cause serious health risks
Hello, accidently posted in wrong forum so wanted to post to Histogen forum and maybe get a response...
Don't mean to be a downer for Histogen, just want to know if anyone out there who is familiar with the science behind Histogen that can add any info on the safety/risks of Histogen and Wnt proteins. I am not very knowledgeable with it or about science in general, but just reading the wikipedia page of "wnt signaling" gives me some worry...
"Traditionally, it is assumed that Wnt proteins can act as Stem Cell Growth Factors, promoting the maintenance and proliferation of stem cells.[32]
However, a recent study conducted by the Stanford University School of Medicine revealed that Wnt appears to block proper communication, with the Wnt signaling pathway having a negative effect on stem cell function. Thus, in the case of muscle tissue, the misdirected stem cells, instead of generating new muscle cells (myoblasts), differentiated into scar-tissue-producing cells called fibroblasts. The stem cells failed to respond to instructions, actually creating wrong cell types."
Elsewhere, I also heard that there's no telling what will be the longer term 5-10 years of Histogen's effect and there are some very serious possible health risks. Is there a risk that Histogen could even get past Phase 3 without issues and then the formula producing dangerous results in subjects years down the line?
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