Safety of Histogen and Wnt protein -
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  1. #1
    Join Date
    Feb 2012

    Default Safety of Histogen and Wnt protein

    Anyone out there who is familiar with the science behind Histogen that can add any info on the safety/risks of Histogen and Wnt protein. I am not very knowledgeable with it or about science in general, but just reading the wikipedia page of "wnt signaling" gives me some worry...

    "Traditionally, it is assumed that Wnt proteins can act as Stem Cell Growth Factors, promoting the maintenance and proliferation of stem cells.[32]
    However, a recent study conducted by the Stanford University School of Medicine revealed that Wnt appears to block proper communication, with the Wnt signaling pathway having a negative effect on stem cell function. Thus, in the case of muscle tissue, the misdirected stem cells, instead of generating new muscle cells (myoblasts), differentiated into scar-tissue-producing cells called fibroblasts. The stem cells failed to respond to instructions, actually creating wrong cell types."

    Is there a risk that Histogen could even get past Phase 3 without issues and then the formula producing dangerous results in subjects years down the line?

  2. #2
    Join Date
    Feb 2012


    Sorry, I'd delete this post and/or move it to the Histogen subforum if I could.

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