Hair loss understood and explained.

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  • beatinghairloss
    Senior Member
    • May 2012
    • 213

    #16
    Hey thanks

    Comment

    • PatientlyWaiting
      Senior Member
      • Jan 2011
      • 1637

      #17
      Propecia works by reducing the size of the prostate and it was later that it was discovered to grow hair on balding crowns of men.
      This is false.

      Myth: Propecia was originally a prostate medication that was found to prevent hair loss.
      Fact: Propecia is not a prostate medication that was by chance noted to have a side effect of hair growth, it is a medication that was known since its discovery that it could grow hair.


      Discover Propecia (Finasteride) for hair loss treatment, expertly reviewed by Dr. Robert M. Bernstein. Learn about its benefits, usage, and effectiveness today!

      Comment

      • beatinghairloss
        Senior Member
        • May 2012
        • 213

        #18
        Your wrong

        History

        In 1974, Julianne Imperato-McGinley of Cornell Medical College in New York attended a conference on birth defects. She reported on a group of hermaphroditic children in the Caribbean who appeared sexually ambiguous at birth, and were initially raised as girls, but then grew external male genitalia and other masculine characteristic post-onset of puberty. Her research group found that these children shared a genetic mutation, causing deficiency of the 5α-reductase enzyme and male hormone dihydrotestosterone (DHT), which was found to have been the etiology behind abnormalities in male sexual development. Upon maturation, these individuals were observed to have smaller prostates which were underdeveloped, and were also observed to lack incidence of male pattern baldness.[47][48]

        In 1975, copies of Imperato-McGinley's presentation were seen by P. Roy Vagelos, who was then serving as Merck's basic-research chief. He was intrigued by the notion that decreased levels of DHT led to the development of smaller prostates. Dr. Vagelos then sought to create a drug which could mimic the condition found in the pseudo-hermaphroditic children in order to treat older men who were suffering from benign prostatic hyperplasia.[49]

        In 1992, finasteride (5 mg) was approved by the U.S. Food and Drug Administration (FDA) for treatment of benign prostatic hyperplasia (BPH), which Merck marketed under the brand name Proscar.

        In 1997, Merck was successful in obtaining FDA approval for a second indication of finasteride (1 mg) for treatment of male pattern baldness (MPB), which was marketed under the brand name Propecia.


        work cited: http://en.wikipedia.org/wiki/Finasteride

        I have this original release of 1992 in news article.



        If I was you I wouldn't be citing bernsteinmedical anymore apparently they are not very reliable.

        Comment

        • beatinghairloss
          Senior Member
          • May 2012
          • 213

          #19
          What happens if your unable to convert T to DHT

          5-Alpha Reductase deficiency

          At puberty, individuals often have primary amenorrhoea and may experience virilization. This may include descending of the testes, hirsutism (facial/body hair considered normal in males - not to be confused with hypertrichosis), deepening of the voice, and enlargement of the clitoris. In adulthood, individuals do not experience male-pattern baldness.[1] As DHT is a far more potent androgen than testosterone alone, virilization in those lacking DHT may be absent or reduced compared to males with functional 5-ARD. It is hypothesized that rising testosterone levels at the start of puberty (around age twelve) are able to generate sufficient levels of DHT either by the action of 5α-reductase type I (active in the adult liver, non-genital skin and some brain areas) or through the expression of low levels of 5α-reductase type II in the testes.



          You see if your prostate cant make DHT your liver and skin can but apparently not enough to cause hair loss. I didn't go into this research with my mind set. I didn't choose to single out ejaculations....no. All roads lead to one conclusion. I have spent hours, days, weeks, years carefully collecting all data from both sides and have come to one conclusion. Ejaculation is the secret culprit "accelerating" hair loss and most men will not believe it no matter how pressing the evidence is. I suppose most of you feel like me.....It's not worth the trade off. So take it for what its worth enjoy your sex life but don't deny your self the knowledge of knowing theres a choice.

          Case Closed

          Comment

          • beatinghairloss
            Senior Member
            • May 2012
            • 213

            #20
            Correction

            I said in my original post Motrin is a vasodilator I ment to say vasoconstrictor this was a typo.****

            Comment

            • beatinghairloss
              Senior Member
              • May 2012
              • 213

              #21
              Botox study was not working



              heres the link that works. The original post link did not work.

              Comment

              • beatinghairloss
                Senior Member
                • May 2012
                • 213

                #22
                Love this explanation

                Comment

                • greatjob!
                  Senior Member
                  • Aug 2011
                  • 909

                  #23
                  ^that is literally the dumbest site ever. Are you the author? Will you please stop peddling this nonsense no one is buying.

                  Comment

                  • 2020
                    Senior Member
                    • Jan 2012
                    • 1513

                    #24
                    botox downregulates inflammation which helps with MPB. Remember that study about elevated PGD2? Again, this has nothing to do with circulation or galea

                    Comment

                    • NeedHairASAP
                      Senior Member
                      • Jul 2011
                      • 1408

                      #25
                      Originally posted by beatinghairloss
                      send your paper to nature, or anywhere, and lets see what the critics have to say.



                      Some questions concerning baldness which
                      were raised by Dr. Ballenger’s comments in The Journal,
                      June 27, may be answered by observations which I made
                      while serving as technician in gross anatomy at the College of
                      Medicine of the University of Illinois (1916-1917). I then had
                      occasion to remove the brains of about 80 cadavers for separate
                      use in the neurology classes and incidentally noted a seemingly
                      obvious relation between the blood (vessel) supply to the scalp
                      and the quantity of hair. Baldness occurred in persons in whom
                      calcification of the skull bones apparently had not only firmly
                      knitted the cranial sutures but also closed or narrowed various
                      small foramens through which blood vessels pass, most prominently
                      in persons with a luxuriant crop of hair. These blood
                      vessels are mainly veins which normally communicate with the
                      diploic veins in the spongy tissue of the skull bones but which
                      are evidently pinched off by calification of the foramens. Various
                      stages of this process of impairing the blood circulation of
                      the scalp could be observed.This, then, not only explains why baldness occurs but also why men are more likely to become bald than women, since
                      bone growth or calcification is generally greater in males than
                      in females. Obviously “hair tonics” or vitamins are not likely to
                      restore a blood circulation through what has practically become
                      “solid ivory.” Moreover, one wonders whether the promotion
                      of a higher calcium intake among adults may not eventually
                      increase the incidence of baldness and the sales of its vaunted
                      remedies.

                      Comment

                      • beatinghairloss
                        Senior Member
                        • May 2012
                        • 213

                        #26
                        Originally posted by greatjob!
                        ^that is literally the dumbest site ever. Are you the author? Will you please stop peddling this nonsense no one is buying.
                        Im not but I strongly agree with him.

                        Comment

                        • beatinghairloss
                          Senior Member
                          • May 2012
                          • 213

                          #27
                          @Needhairasap.

                          Thats a great point. FYI. I do not eat dairy because of the calsification in blood vessels. I have a study that says it decreases blood flow and increases risk of stroke by 30%.

                          Comment

                          • beatinghairloss
                            Senior Member
                            • May 2012
                            • 213

                            #28
                            Originally posted by 2020
                            botox downregulates inflammation which helps with MPB. Remember that study about elevated PGD2? Again, this has nothing to do with circulation or galea
                            Vascular changes

                            Acute inflammation is characterized by marked vascular changes, including vasodilation, increased permeability and the slowing of blood flow, which are induced by the actions of various inflammatory mediators. Vasodilation occurs first at the arteriole level, progressing to the capillary level, and brings about a net increase in the amount of blood present, causing the redness and heat of inflammation. Increased permeability of the vessels results in the movement of plasma into the tissues, with resultant stasis due to the increase in the concentration of the cells within blood - a condition characterized by enlarged vessels packed with cells. Stasis allows leukocytes to marginate (move) along the endothelium, a process critical to their recruitment into the tissues. Normal flowing blood prevents this, as the shearing force along the periphery of the vessels moves cells in the blood into the middle of the vessel.

                            Work Cited: http://en.wikipedia.org/wiki/Inflammation

                            Comment

                            • 2020
                              Senior Member
                              • Jan 2012
                              • 1513

                              #29
                              ^ how does that support your argument?

                              Comment

                              • NeedHairASAP
                                Senior Member
                                • Jul 2011
                                • 1408

                                #30
                                Originally posted by beatinghairloss
                                Im not but I strongly agree with him.
                                so, considering your theory, you must think the hypoxic nature of loreal's new lotion may be helpful?

                                Comment

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