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  1. #12
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    The problem regarding PFS is far more complex, those natural remedies may have a slight impact for a few days but even with the most involved techniques patients often relapse after a week or so. The body realises that you are trying to upregulate a certain androgen/chemical, so it works against you to find its own 'balance'.

    The best explanation researchers have at the moment is that finasteride has either reduced or killed off a portion of androgen receptors in the body, that the drug has resulted in a lower intracellular activity of the compound 5AR and/or that the body has somehow developed a kind of resistance to some androgens. They need to compare androgen ratios between FIN users and healthy users, the fact that SOME people respond well to higher doses of TEST indicates a receptor issue.

    There are a lot of explanations, but, when it comes to the endocrine system, the body has a mind of its own, I think it has treated finasteride as a virus/bacteria or some foreign object and learnt the way it enacts on cells and the endocrine system holistically, therefore the body then imitates the actions of the drug for years after quitting, possibly indefinately.


    ^^that last paragraph is my own theory so feel free to shoot it down, give me your input with reference to journals.

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