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Senior Member
Dr. Irwig’s Propecia study, was it funded by attorneys suing Merck?
http://www.cnn.com/2012/07/13/health...rug/index.html
Did I hear this right? Did the CNN medical reporter say that Dr. Irwig took money from attorney's suing Merck? So does this mean that Iriwig’s Propecia study was funded by the very attorneys representing the study participants? This is crazy if it’s true!
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On his published manuscript he doesn't declare any conflicts of interest which would have to be declared if it were the case
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Senior Member
Originally Posted by rm056789
On his published manuscript he doesn't declare any conflicts of interest which would have to be declared if it were the case
Irwig is supposed to disclose that information, so we all assume that he would, but the CNN health reporter clearing made a point of stating the Irwig did take money from these attorneys and this is the first I have ever heard of this. If the attorneys who are suing Merck are actually the ones who funded this study or gave Irwig any kickbacks then it's pretty shady. How do we find out more about this?
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One way I can think to reconcile these things is if Irwig has taken money from attorneys suing Merck, but those attorneys' money was not used to fund the study itself, in which case I'm thinking he wouldn't have needed to disclose a conflict of interest?
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Senior Member
Originally Posted by 25 going on 65
One way I can think to reconcile these things is if Irwig has taken money from attorneys suing Merck, but those attorneys' money was not used to fund the study itself, in which case I'm thinking he wouldn't have needed to disclose a conflict of interest?
Legally he might not have to disclose this after the fact, but ethically, how can any legitimate clinical investigator take kickbacks from attorneys trying to shake down Merck. There is no way to reconcile that, it's shady all the way if this is true.
What was it like, the attorneys said, “way to go Irwig, you really shook things up! Here's 10k for the hard work.” There is no need for the attorneys to give Irwig any money after the fact, it they did give him the cash then it was probably part of the whole plan. These attorneys needed something to hang their hats on and this study gave them what they needed. Now with all of the media pressure they will probably end up with a multi million dollar settlement for themselves and their clients just to go away.
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I didn't mean it would be ethical, just that it might explain the lack of disclosure if he took money from those attorneys.
To be honest I don't think his series of case studies are necessarily useless, but they are being so widely misinterpreted (a lot of it is due to bad reporting--headlines like "96% of fin users have permanent sides") that more harm has been done than good.
imo a more helpful bit of evidence for PFS was the Merck study on 5 mg finasteride, where something like .5-1% of users got sides that didn't fully resolve after six months. Of course that was done on a bunch of old guys with prostate problems taking 5 mg per day, so the risk would presumably be lower for younger healthy guys taking 1-1.25 mg for hair.
I also wouldn't say it demonstrates irreversible sides since unwanted effects from drugs can go on for months or years before resolving on their own, and also some people have recovered from lingering fin sides by seeking medical treatment (this would not happen for sides that were "permanent" or "irreversible").
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