Propecia/Fin SHould be scrapped for good

[25 going on 65]

it's really not worth it especially as you will probably lose your hair from your genes anyway.

To me and many others it's definitely worth it, no question. If my endocrine system crashes in 10-15 years it would still be worth it.

All drugs have side effects. Some very dangerous and some long-term. Finasteride is a prostate medication with a low rate of sides; things like benzos are much more dangerous and are known to potentially cause years of unwanted effects after quitting. They won't be taken off the market because they still are helpful to a lot of patients.
Every drug you put in/on your body is a gamble. No one is forcing anyone to take the risk. I tried minoxidil for a brief time and was allergic; my face felt like a giant hand stuffed into a tiny alcohol-coated latex glove. So I quit using it. I don't want to ban the drug and take its benefits away from the millions of men and women who gladly accept the risks and use it every day.

[UK_]

Because it works for the majority and the majority of those who use it do not experience the possible side effects. It's that simple.

It is not at all likely that it would be scrapped at all - much less scrapped for good. Some birth control pills and anti-depressants have much more serious side effect profiles. They haven't been scrapped.

The majority, not the minority. That is reality. Most men who use Finasteride do not experience the possible side effects. That is also reality, whether you like it or not, it is what it is.

"Doctors have described taking Propecia as being on par with people playing Russian roulette with their sex drives."

"In a group of 54 otherwise healthy former users of finasteride who developed persistent sexual side effects that lasted for at least 3 months, 96% continued to experience these effects when reassessed 9–16 months (mean 14 months) later, raising the possibility of permanent effects."


"There is a solid and growing body of basic science evidence that finasteride reduces the concentrations of several neuroactive steroids that play a role in neurogenesis and neuronal survival."


"To explain the long-term neurological effects of finasteride, it is possible that reduced concentrations of neuroactive steroids are affecting the plasticity of neuronal architecture in regions of the brain responsible for sexual function."


"Another recently published study found that rats treated with finasteride for 4 weeks had a 26% reduction in the weight of their corpora cavernosa as compared with a control group [27]. This finding is consistent with the reports of genital shrinkage reported by some of the human subjects in this study."


"The most volunteered changes related to the urogenital system in terms of semen quality and decreased ejaculate volume, reduction in penis size, penile curvature or reduced sensation, fewer spontaneous erections, decreased testicular size, testicular pain, and prostatitis. Many subjects also noted changes to their mental abilities, sleeping patterns, and/or depressive symptoms. Many subjects reported a “disconnection” between the mental and physical aspects of sexual function."


"The typical story of men with persistent sexual and other side effects is that they unsuccessfully seek help from various providers in multiple medical specialties. It is important for physicians to acknowledge with their patients the current limitations in medical knowledge, particularly as it relates to neuroscience. There is no known blood or imaging test to study or measure neuroactive steroids or their metabolites in different areas of the brain associated with sexual function."


"Further valuable research could determine who would be susceptible to finasteride through genetic studies of polymorphisms of 5a reductase and the androgen receptor. Further research with validated instruments is needed to study the nonsexual persistent side effects associated with finasteride."


"When the Food and Drug Administration approved the hair-growth drug Propecia in 1997, a number of doctors and medical researchers voiced their strong concerns about the drug’s severe side effects. One outspoken critic was well-known hair-restoration expert L. Lee Bosley who publicly denounced Propecia as a "serious health concern" in the wake of its FDA approval—only to allow his doctors to enthusiastically recommend the medication to patients a few years later.


On Dec. 24, 1997, Bosley Medical—which bills itself as "The World's Most Experienced Hair Restoration Experts" and today boasts some 70 offices in the U.S., Canada, Mexico and China—issued a news release via paid-distribution service Business Wire. Headlined "Supposed Miracle Baldness Cure Creates Serious Health Concerns Among Hair Restoration Professionals," that release (still housed on LexisNexis) quoted Dr. Bosley as saying of Propecia:


"The FDA has just approved a drug that has the capability to impair male sexual performance, creating the inability to achieve an erection [and] decreases libido... The potential side effects, especially the long-term side effects of the drug, should be the overriding concerns to both the users and the manufacturer."


Dr. Bosley also said of Propecia (generic name: finasteride) that "the results attained during the clinical trials would immediately be dismissed as unacceptable by our standards." All of which is enormously ironic, say Bosley patients, particularly the assertion about Propecia being unacceptable by the standards of Dr. Bosley. For as shortly as three years after Dr. Bosley issued his stern warning of Propecia, Bosley Medical doctors began prescribing the risky drug.


Within a few months of starting on Propecia, [Julian] Parks says he developed excruciating pain in one testicle, which lasted two years. A few years later, while still on the drug—though at half-dose—he says he developed Peyronie's disease, a painful disorder characterized by the growth of fibrous scar tissue inside the penis, which often causes curvature of the erect organ. Parks, who says he previously had no major health concerns, finally quit the drug in 2006 after suffering other side effects. To this day, most of them have yet to resolve themselves.


Seven weeks after starting on finasteride, the previously healthy [Thomas] Schultz says he became extremely depressed and was beset by panic attacks. That while witnessing his genitals shrink to tiny proportions and grow completely numb. And though he quit the drug two weeks later, Schultz says his health rapidly worsened.


Among his side effects—which continue to afflict him to this day—have been loss of libido, impotence, breast enlargement, prostate pain, muscle aches, cognitive dysfunction, anhedonia and severe insomnia, as well as Peyronie's disease. Meanwhile, Schultz says he has consulted some of L.A.'s top urologists, neurologists and endocrinologists, all of whom have told him there's nothing they can do to help. When Schultz discovered that Dr. Bosley had issued a press release in 1997 warning of Propecia's dangers, he said, "I grew sick to my stomach at his betrayal of innocent, unsuspecting people like myself."


Known clinically as Post-Finasteride Syndrome, the condition that has ravaged Shultz, Parks and thousands like them around the globe is marked by sexual, neurological, hormonal and physical side effects—including impotence, Peyronie's disease, testosterone deficiency and depression—that do not resolve themselves after quitting Propecia."

[25 going on 65]

"Doctors have described taking Propecia as being on par with people playing Russian roulette with their sex drives."

"In a group of 54 otherwise healthy former users of finasteride who developed persistent sexual side effects that lasted for at least 3 months, 96% continued to experience these effects when reassessed 9–16 months (mean 14 months) later, raising the possibility of permanent effects."


"There is a solid and growing body of basic science evidence that finasteride reduces the concentrations of several neuroactive steroids that play a role in neurogenesis and neuronal survival."


"To explain the long-term neurological effects of finasteride, it is possible that reduced concentrations of neuroactive steroids are affecting the plasticity of neuronal architecture in regions of the brain responsible for sexual function."


"Another recently published study found that rats treated with finasteride for 4 weeks had a 26% reduction in the weight of their corpora cavernosa as compared with a control group [27]. This finding is consistent with the reports of genital shrinkage reported by some of the human subjects in this study."


"The most volunteered changes related to the urogenital system in terms of semen quality and decreased ejaculate volume, reduction in penis size, penile curvature or reduced sensation, fewer spontaneous erections, decreased testicular size, testicular pain, and prostatitis. Many subjects also noted changes to their mental abilities, sleeping patterns, and/or depressive symptoms. Many subjects reported a “disconnection” between the mental and physical aspects of sexual function."


"The typical story of men with persistent sexual and other side effects is that they unsuccessfully seek help from various providers in multiple medical specialties. It is important for physicians to acknowledge with their patients the current limitations in medical knowledge, particularly as it relates to neuroscience. There is no known blood or imaging test to study or measure neuroactive steroids or their metabolites in different areas of the brain associated with sexual function."


"Further valuable research could determine who would be susceptible to finasteride through genetic studies of polymorphisms of 5a reductase and the androgen receptor. Further research with validated instruments is needed to study the nonsexual persistent side effects associated with finasteride."


"When the Food and Drug Administration approved the hair-growth drug Propecia in 1997, a number of doctors and medical researchers voiced their strong concerns about the drug’s severe side effects. One outspoken critic was well-known hair-restoration expert L. Lee Bosley who publicly denounced Propecia as a "serious health concern" in the wake of its FDA approval—only to allow his doctors to enthusiastically recommend the medication to patients a few years later.


On Dec. 24, 1997, Bosley Medical—which bills itself as "The World's Most Experienced Hair Restoration Experts" and today boasts some 70 offices in the U.S., Canada, Mexico and China—issued a news release via paid-distribution service Business Wire. Headlined "Supposed Miracle Baldness Cure Creates Serious Health Concerns Among Hair Restoration Professionals," that release (still housed on LexisNexis) quoted Dr. Bosley as saying of Propecia:


"The FDA has just approved a drug that has the capability to impair male sexual performance, creating the inability to achieve an erection [and] decreases libido... The potential side effects, especially the long-term side effects of the drug, should be the overriding concerns to both the users and the manufacturer."


Dr. Bosley also said of Propecia (generic name: finasteride) that "the results attained during the clinical trials would immediately be dismissed as unacceptable by our standards." All of which is enormously ironic, say Bosley patients, particularly the assertion about Propecia being unacceptable by the standards of Dr. Bosley. For as shortly as three years after Dr. Bosley issued his stern warning of Propecia, Bosley Medical doctors began prescribing the risky drug.


Within a few months of starting on Propecia, [Julian] Parks says he developed excruciating pain in one testicle, which lasted two years. A few years later, while still on the drug—though at half-dose—he says he developed Peyronie's disease, a painful disorder characterized by the growth of fibrous scar tissue inside the penis, which often causes curvature of the erect organ. Parks, who says he previously had no major health concerns, finally quit the drug in 2006 after suffering other side effects. To this day, most of them have yet to resolve themselves.


Seven weeks after starting on finasteride, the previously healthy [Thomas] Schultz says he became extremely depressed and was beset by panic attacks. That while witnessing his genitals shrink to tiny proportions and grow completely numb. And though he quit the drug two weeks later, Schultz says his health rapidly worsened.


Among his side effects—which continue to afflict him to this day—have been loss of libido, impotence, breast enlargement, prostate pain, muscle aches, cognitive dysfunction, anhedonia and severe insomnia, as well as Peyronie's disease. Meanwhile, Schultz says he has consulted some of L.A.'s top urologists, neurologists and endocrinologists, all of whom have told him there's nothing they can do to help. When Schultz discovered that Dr. Bosley had issued a press release in 1997 warning of Propecia's dangers, he said, "I grew sick to my stomach at his betrayal of innocent, unsuspecting people like myself."


Known clinically as Post-Finasteride Syndrome, the condition that has ravaged Shultz, Parks and thousands like them around the globe is marked by sexual, neurological, hormonal and physical side effects—including impotence, Peyronie's disease, testosterone deficiency and depression—that do not resolve themselves after quitting Propecia."

Doesn't sound half as bad as balding.

Genital shrinkage, the ultimate man-scaring phenomenon--soon we'll hear about fin reducing your ability to shoot large firearms and brew strong coffee.
Wait, maybe those are just American-scaring phenomenons.

Edit: lol Bosley.

[Tracy C]

Mentalist,

The words some and all DO NOT mean the same thing. I said some, not all. Do not twist my words just to keep your fear mongering going.

There is nothing ridiculous about anything I said. It is all 100% the truth. You don't have to like it if you don't want to - but it is the truth.

If you do not want to take Finasteride, don't take it - but it should not be taken away from those who do want to use it and are benefiting from it.

[Mentalist]

I realise what you said, and i know the difference so stop backtracking cos you realise I have a point when are you ever going to accept that you're not always right proecia is not a perfect nor effective long term and is USELESS for agressive hair loss anyway. and take a chill pill

[WarLord]

"Doctors have described taking Propecia as being on par with people playing Russian roulette with their sex drives."

"In a group of 54 otherwise healthy former users of finasteride who developed persistent sexual side effects that lasted for at least 3 months, 96% continued to experience these effects when reassessed 9–16 months (mean 14 months) later, raising the possibility of permanent effects."


"There is a solid and growing body of basic science evidence that finasteride reduces the concentrations of several neuroactive steroids that play a role in neurogenesis and neuronal survival."


"To explain the long-term neurological effects of finasteride, it is possible that reduced concentrations of neuroactive steroids are affecting the plasticity of neuronal architecture in regions of the brain responsible for sexual function."


"Another recently published study found that rats treated with finasteride for 4 weeks had a 26% reduction in the weight of their corpora cavernosa as compared with a control group [27]. This finding is consistent with the reports of genital shrinkage reported by some of the human subjects in this study."


"The most volunteered changes related to the urogenital system in terms of semen quality and decreased ejaculate volume, reduction in penis size, penile curvature or reduced sensation, fewer spontaneous erections, decreased testicular size, testicular pain, and prostatitis. Many subjects also noted changes to their mental abilities, sleeping patterns, and/or depressive symptoms. Many subjects reported a “disconnection” between the mental and physical aspects of sexual function."


"The typical story of men with persistent sexual and other side effects is that they unsuccessfully seek help from various providers in multiple medical specialties. It is important for physicians to acknowledge with their patients the current limitations in medical knowledge, particularly as it relates to neuroscience. There is no known blood or imaging test to study or measure neuroactive steroids or their metabolites in different areas of the brain associated with sexual function."


"Further valuable research could determine who would be susceptible to finasteride through genetic studies of polymorphisms of 5a reductase and the androgen receptor. Further research with validated instruments is needed to study the nonsexual persistent side effects associated with finasteride."


"When the Food and Drug Administration approved the hair-growth drug Propecia in 1997, a number of doctors and medical researchers voiced their strong concerns about the drug’s severe side effects. One outspoken critic was well-known hair-restoration expert L. Lee Bosley who publicly denounced Propecia as a "serious health concern" in the wake of its FDA approval—only to allow his doctors to enthusiastically recommend the medication to patients a few years later.


On Dec. 24, 1997, Bosley Medical—which bills itself as "The World's Most Experienced Hair Restoration Experts" and today boasts some 70 offices in the U.S., Canada, Mexico and China—issued a news release via paid-distribution service Business Wire. Headlined "Supposed Miracle Baldness Cure Creates Serious Health Concerns Among Hair Restoration Professionals," that release (still housed on LexisNexis) quoted Dr. Bosley as saying of Propecia:


"The FDA has just approved a drug that has the capability to impair male sexual performance, creating the inability to achieve an erection [and] decreases libido... The potential side effects, especially the long-term side effects of the drug, should be the overriding concerns to both the users and the manufacturer."


Dr. Bosley also said of Propecia (generic name: finasteride) that "the results attained during the clinical trials would immediately be dismissed as unacceptable by our standards." All of which is enormously ironic, say Bosley patients, particularly the assertion about Propecia being unacceptable by the standards of Dr. Bosley. For as shortly as three years after Dr. Bosley issued his stern warning of Propecia, Bosley Medical doctors began prescribing the risky drug.


Within a few months of starting on Propecia, [Julian] Parks says he developed excruciating pain in one testicle, which lasted two years. A few years later, while still on the drug—though at half-dose—he says he developed Peyronie's disease, a painful disorder characterized by the growth of fibrous scar tissue inside the penis, which often causes curvature of the erect organ. Parks, who says he previously had no major health concerns, finally quit the drug in 2006 after suffering other side effects. To this day, most of them have yet to resolve themselves.


Seven weeks after starting on finasteride, the previously healthy [Thomas] Schultz says he became extremely depressed and was beset by panic attacks. That while witnessing his genitals shrink to tiny proportions and grow completely numb. And though he quit the drug two weeks later, Schultz says his health rapidly worsened.


Among his side effects—which continue to afflict him to this day—have been loss of libido, impotence, breast enlargement, prostate pain, muscle aches, cognitive dysfunction, anhedonia and severe insomnia, as well as Peyronie's disease. Meanwhile, Schultz says he has consulted some of L.A.'s top urologists, neurologists and endocrinologists, all of whom have told him there's nothing they can do to help. When Schultz discovered that Dr. Bosley had issued a press release in 1997 warning of Propecia's dangers, he said, "I grew sick to my stomach at his betrayal of innocent, unsuspecting people like myself."


Known clinically as Post-Finasteride Syndrome, the condition that has ravaged Shultz, Parks and thousands like them around the globe is marked by sexual, neurological, hormonal and physical side effects—including impotence, Peyronie's disease, testosterone deficiency and depression—that do not resolve themselves after quitting Propecia."

I think that these guys are psychiatric cases, who would well fit to this forum. There is a plenty of their colleagues here.

[beatinghairloss]

This should be scrapped with all the side affects it should've never had FDA Approval in my opinion. I can understand why people to a certain extent obviously try and halt their hair loss but in the long term it's really stupid that people are taking this as it doesn't halt hair loss forever while you keep taking it or not as hair loss is not just down to DHT and stuff it's down to genetics too and I don't think anybody should be taking it with the serious side effects. It shouldn't even be on the shelves. I'll never really get my head around why people take these pills.

If you have read any of my posts you are well aware that I am against taking the limp pills. So just wanted to add that I agree completely the FDA should be ashamed. There are less risky ways to barely maintain hair.

[25 going on 65]

If you have read any of my posts you are well aware that I am against taking the limp pills. So just wanted to add that I agree completely the FDA should be ashamed. There are less risky ways to barely maintain hair.

Not yet.
10char

[Mentalist]

If you have read any of my posts you are well aware that I am against taking the limp pills. So just wanted to add that I agree completely the FDA should be ashamed. There are less risky ways to barely maintain hair.

Thank you.