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  1. #1
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    Default Ketoconazole (shampoo or creme) and PGD2, cox2, etc.

    can we find any connections between the keto and either PGD2 or COX2 or CRTH receptors?


    I guess ketoconazole is nizoral?

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    The CYP17 inhibitor ketoconazole (Scott et al. 2009) reduced testosterone production without affecting PGD2 synthesis (Figure 3D,E).

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    apparenlty keto CREATES MORE PGD2??? that makes no sense


    http://webcache.googleusercontent.co...&ct=clnk&gl=us

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    However, it seems that KCZ also influences themetabolism of cyclooxygenase products. The drug has been shown to inhibit thesynthesis of thromboxane [7] while concomitantly stimulating thesynthesis of prostaglandins PGE2 and PGD2
    doesn't give any numbers though... PGE2 stimulation could be much higher than PGD2 so extra PGE2 may offset the inhibiting effect of PGD2?

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    Quote Originally Posted by 2020 View Post
    doesn't give any numbers though... PGE2 stimulation could be much higher than PGD2 so extra PGE2 may offset the inhibiting effect of PGD2?
    I don't follow you

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    Quote Originally Posted by NeedHairASAP View Post
    I don't follow you
    PGD2 increase by 20%
    PGE2 increase by 50%

    that would still give you a positive effect even if PGD2 is slightly increased

  7. #7
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    Quote Originally Posted by NeedHairASAP View Post
    can we find any connections between the keto and either PGD2 or COX2 or CRTH receptors?


    I guess ketoconazole is nizoral?
    you can get keto in foam form, i purchased it a few years back i cant remember where from though.

    http://www.rxlist.com/extina-drug.htm

  8. #8
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    Quote Originally Posted by 2020 View Post
    PGD2 increase by 20%
    PGE2 increase by 50%

    that would still give you a positive effect even if PGD2 is slightly increased
    I don't know what PGE2 is... thats a pro*****liinwhatever that coutneracts PGD2?

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    Quote Originally Posted by gutted View Post
    you can get keto in foam form, i purchased it a few years back i cant remember where from though.

    http://www.rxlist.com/extina-drug.htm

    hmm, well people have been using it for years and havn't gotten significant regrowth, so perhaps that wasn't it. It did help with the itch tho, and cleared up my scale scalp REAL well.

  10. #10
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    I've been applying keto 2% cream on my temples 2 times a day for about 6 months. It did nothing for me :/

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