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  1. #11
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    Quote Originally Posted by gutted View Post
    pgd2 is upregulated anywhere where there is inflamation present, it can also be found upregulated in wounds, scars...

    this can easily state the obvious, that the body is attacking something and itself, which it is, the traditional theory may state its dht, which it probably is not and i believe it not to be.
    there probably is an infection going on in follicular cells.

    transplanted follciles/sebcaceous glands are genetically immune in the sense they dont have a high sensitivity to androgens and so dont take androgens up as much as balding susceptible follciles/glands... when hair from donor regions is trasplanted its sebcaceous gland is also taken with the follicle.
    Mice treated with PGD2 lost their fur in the treated area. There is little doubt PGD2 is part of an active chain of events following the androgen receptor. Nothing's flawed about the research. Prostaglandins are simply molecules which act as "local" signals and don't necessarily produce inflamation. In fact, they have a multitude of roles which have nothing to do with inflamation at all.

    Research: http://stm.sciencemag.org/content/4/...6ra34.abstract
    Prostaglandin info: http://en.wikipedia.org/wiki/Prostaglandin

  2. #12
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    Quote Originally Posted by Aston View Post
    Mice treated with PGD2 lost their fur in the treated area. There is little doubt PGD2 is part of an active chain of events following the androgen receptor. Nothing's flawed about the research. Prostaglandins are simply molecules which act as "local" signals and don't necessarily produce inflamation. In fact, they have a multitude of roles which have nothing to do with inflamation at all.

    Research: http://stm.sciencemag.org/content/4/...6ra34.abstract
    Prostaglandin info: http://en.wikipedia.org/wiki/Prostaglandin
    i said they are upregulated in inflamed areas.

    your link to wikipedia -
    "prostaglandin levels are increased by COX-2 in scenarios of inflammation."

    prostglandins are involved with inflamation.

    pgd2 and its role in inflammation.
    http://www.caymanchem.com/app/templa...326280AABDD091

  3. #13
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    Quote Originally Posted by Aston View Post
    Mice treated with PGD2 lost their fur in the treated area. There is little doubt PGD2 is part of an active chain of events following the androgen receptor. Nothing's flawed about the research. Prostaglandins are simply molecules which act as "local" signals and don't necessarily produce inflamation. In fact, they have a multitude of roles which have nothing to do with inflamation at all.

    Research: http://stm.sciencemag.org/content/4/...6ra34.abstract
    Prostaglandin info: http://en.wikipedia.org/wiki/Prostaglandin
    i said the theory that dht targeting the androgen receptor on the hair follicle causing minituarisation is flawed.

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