PGD2 causes hair loss according to Dr. Cotsarelis

[Pate]

I've been wondering, since Cotsarelis is heading up Follica, and that treatment (from what we know) doesn't target PGD2, how does that affect the chances of Follica being released? We obviously don't know anything about their phase 2 results or if they're even planning for phase 3. But do you think this recent discovery negates Follica's method as to what sparks regrowth of hair?

It doesn't negate Follica's other research, which we don't know much about because it's kept tightly under wraps but seems to involve wounding and lithium carbonate, a drug for bipolar disorder.

But to be honest I don't expect much from Follica. They seem to be making only a half-hearted effort towards commercialising their work and Cotsarelis seems to be more interested in the research than the practice. This is why some guys here get on his case, but I don't see the problem with it. He's making some good discoveries, it's just the ungrateful pr*cks on this board who seem to think he was put on this earth to fix their own personal hair loss.

You would think Cotsarelis would be promoting his own product, yet in the interview video posted earlier in this thread he instead suggests that an effective MPB treatment could come from the PGD2 blocking drugs currently in clinical trials.

If you read some of the earlier stuff on this thread you will see that several of the guys involved in the study with Cotsarelis work for companies that have patents over those PGD2 blocking drugs. So it's not Cotsarelis personally who's benefitting but several of the other study authors are.

[Mojo Risin]

I don't agree with you Mojo. You're such a drama queen - you must by gay. And balding gay guys are the worst.

Oh ! Nice homophobia right there.

I'd rather be realistic. But if you prefer licking Cotsarelis's ass with his ''findings'' ... go on buddy.

[Thermal]

here you go broseph :

http://www.2shared.com/document/6a9BdoTG/jm701509k.html

Thanks. Much appreciated.

[Maradona]

Oh ! Nice homophobia right there.

I'd rather be realistic. But if you prefer licking Cotsarelis's ass with his ''findings'' ... go on buddy.

He got insane media attention for something discovered long time ago.
I wonder how he did it.

I even saw this shit on my local news...a channel of my town only.

[Kiwi]

Oh ! Nice homophobia right there.

I'd rather be realistic. But if you prefer licking Cotsarelis's ass with his ''findings'' ... go on buddy.

I'll leave the ass licking to you

[sausage]

I love ass licking, I would love to lick Cheryl Cole's beautiful ass.

[NotBelievingIt]

I love ass licking, I would love to lick Cheryl Cole's beautiful ass.

you're on the wrong website for that!

[gmonasco]

Our Body's Balancing Signals for Hair Loss and More

So while the March 2012 article in Science Translational Medicine is about prostaglandin D2's role in hair loss, the fact that there is a prostaglandin F2-alpha that increases hair growth, and now we know that D2 decreases hair growth, this is yet another example that demonstrates how for every function in our body, there is an "on" and an "off" switch.

http://www.huffingtonpost.com/julie-chen-md/hair-loss-study_b_1378557.html

[yeahyeahyeah]

So while the March 2012 article in Science Translational Medicine is about prostaglandin D2's role in hair loss, the fact that there is a prostaglandin F2-alpha that increases hair growth, and now we know that D2 decreases hair growth, this is yet another example that demonstrates how for every function in our body, there is an "on" and an "off" switch.

http://www.huffingtonpost.com/julie-...b_1378557.html

So is the cure upping prostaglandin F2-alpha?

[NotBelievingIt]

So is the cure upping prostaglandin F2-alpha?

Likely not. The study didn't say a lack of PGF2-a but an excess of PGD2.

They could be antagnoizers of each other though where PGF2-a increase could result in a PGD2 decrease.

[yeahyeahyeah]

Likely not. The study didn't say a lack of PGF2-a but an excess of PGD2.

They could be antagnoizers of each other though where PGF2-a increase could result in a PGD2 decrease.

well how do you do that?

[NotBelievingIt]

well how do you do that?

lol if I knew I'd make the mobnies first!

[elvispresley]

guys can we create a liste of substances that go against the receptor?


this is a question for the expert off course because i have no idea of waht are the substance:

so I/WE can start to try this substance, specially TOPICALLY , for example vinegar on the bald spot...


thx a lot

[BoSox]

I love how they say "Scientists may have found cure for baldness"


You get excited, then when you read the article it says, "May prevent future baldness, but not reverse hair loss."

How the **** is that a cure for baldness? It's a cure for preventing baldness. It may help me because i still have thinning hair, but hairline no and those who are bald, no.

I just don't understand, they find the root to MPB.. and preventing is the best that can come out of it? :/ I REALLY hope this reverses hair loss 100%.

(my one and only pessimistic comment for the year)

[bearhard]

Sodium cromoglycate (SCG) found to inhibit prostaglandin D2 (PGD2)

http://www.uptodate.com/contents/mast-cells-surface-receptors-and-signal-transduction/abstract/52

Sodium cromoglycate (SCG) found in eye drops

http://www.netdoctor.co.uk/allergy-and-asthma/medicines/opticrom-aqueous-eye-drops.html

http://www.optrex.co.uk/optrex_range/optrex_allergy_eye_drops.php

I'm gonna try it! Doesn't look like a particularly toxic substance if it is safe enough to put into eyes.

So anyone started testing this and got anything to report?