PGD2 causes hair loss according to Dr. Cotsarelis

[Mojo Risin]

And aren't you guys tired of seeing every single findings getting reported by media as a POTENTIAL CURE FOR BALDNESS. I mean ... it gets so frustrating. How many times did we read that in the past 10 years ?

[Pate]

And aren't you guys tired of seeing every single findings getting reported by media as a POTENTIAL CURE FOR BALDNESS. I mean ... it gets so frustrating. How many times did we read that in the past 10 years ?

Sure. But that's the media's fault, not Cotsarelis's. The media don't give a damn about prostaglandin inhibitors and their effect on GPR44 receptor. All they care about is that they can print POTENTIAL CURE FOR BALDNESS and watch the paper sales and the advertising revenue roll in.

I think you're picking on the wrong target. Before fully effective treatments of hair loss can be developed we need to know the exact mechanisms that cause it. Cotsarelis is working on this and doing some groundbreaking research. And if he can ensure continued funding for his research with the occasional media press release, then I say good on him. I'd much rather that than that his centre goes bust through lack of funds, hair loss research comes to a dead end and Cotsarelis goes off to study the life cycle of earwigs, or something.

[Thermal]

Sodium cromoglycate (SCG) found to inhibit prostaglandin D2 (PGD2)

http://www.uptodate.com/contents/mast-cells-surface-receptors-and-signal-transduction/abstract/52

Sodium cromoglycate (SCG) found in eye drops

http://www.netdoctor.co.uk/allergy-and-asthma/medicines/opticrom-aqueous-eye-drops.html

http://www.optrex.co.uk/optrex_range/optrex_allergy_eye_drops.php

I'm gonna try it! Doesn't look like a particularly toxic substance if it is safe enough to put into eyes.

[gutted]

Sodium cromoglycate (SCG) found to inhibit prostaglandin D2 (PGD2)

http://www.uptodate.com/contents/mast-cells-surface-receptors-and-signal-transduction/abstract/52

Sodium cromoglycate (SCG) found in eye drops

http://www.netdoctor.co.uk/allergy-and-asthma/medicines/opticrom-aqueous-eye-drops.html

http://www.optrex.co.uk/optrex_range/optrex_allergy_eye_drops.php

I'm gonna try it! Doesn't look like a particularly toxic substance if it is safe enough to put into eyes.

you could try this -> quercetin

http://www.mastcellmaster.com/documents/Skin-Diseases/Niacin-flush-IJIP.pdf

has been shown to inhibit pgd2.

i think inhibiting pgd2, would yeild really good results at the temples/hairline!

[UK_]

So... After they tested the hair follicle that was immune to the effects of PGD2... was it still affected by DHT?

I can't believe after all this time, this is the best Follica can come out with - I thought back in 2008 they were "just around the corner" lol - another 5 years I take it now? so we're all set for 2017? What happened to the lithium study?

Im guessing Histogen will be releasing some Phase II data at the medical convention this May.

[sausage]

Please someone hurry up with a cure. Having a bad day today. Need hair now!

You can have all my money if you can get all my hair back. You can have my Xbox and all my clothes take everything and give me hair.

[elvispresley]

Sodium cromoglycate (SCG) found to inhibit prostaglandin D2 (PGD2)

http://www.uptodate.com/contents/mast-cells-surface-receptors-and-signal-transduction/abstract/52

Sodium cromoglycate (SCG) found in eye drops

http://www.netdoctor.co.uk/allergy-and-asthma/medicines/opticrom-aqueous-eye-drops.html

http://www.optrex.co.uk/optrex_range/optrex_allergy_eye_drops.php

I'm gonna try it! Doesn't look like a particularly toxic substance if it is safe enough to put into eyes.

let me understand you are going to try to put some eye drops on the bald spot , i understood correctly? i can also try depending on the cost of the eye drops... let me know thx

[bananana]

let me understand you are going to try to put some eye drops on the bald spot , i understood correctly? i can also try depending on the cost of the eye drops... let me know thx

Damn this is exciting!
Guys - I would try the same thing but with added scalproller - I guess it would improve the penetration.

[gutted]

i dont think this new to george and people at UPENN

heres a patent filled in 2007 by them, describing the use of prostglandins to treat mpb, acne, rosacea, prostate cancer, and benign prostatic hypertrophy.

http://www.google.com/patents/US20110021599

i suspect they knew about this a long time ago.

[sausage]

"Up to ten drugs have been identified that can stem PGD2’s activity and may soon be available to buy as creams or ointments."

How soon, if drugs already exist what are they currently treating and why can't we just take them?

or is it a case that they need to refine the drug to suit male pattern baldness and want to market as a hairloss cure including having packaging specific to hairloss?

It is not known if the drug would regrow hair but it should stop it. Hopefully it can grow hair otherwise it won't be much use to me. Although if I kept what I have it would be easier for me to have a HT as i'd have enough donor.

[UK_]

http://www.dailymail.co.uk/sciencetech/article-2118277/Cure-baldness-sale-years.html

There's a video at the bottom if you havent already seen it.

[clandestine]

http://www.dailymail.co.uk/sciencete...ale-years.html

There's a video at the bottom if you havent already seen it.

Title is hilarious; "Cure for baldness in could be on sale within five years"

Hear that? Only 5 more years, guys!

[elvispresley]

i found this article maybe is interesting is a test :

http://www.biomedcentral.com/content/pdf/1756-0500-4-47.pdf

so guys lets make a list of product who contain the SCG . i would like to try

do u think it could be dangerous and have side effects?

[UK_]

Title is hilarious; "Cure for baldness in could be on sale within five years"

Hear that? Only 5 more years, guys!

I know ... tell me about it.

[Losing_It]

Now where did I leave that time machine? 2017 here I come. Cotsarelis, the original internet troll