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  1. #1
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    CB-03-01, a molecule patented by Cosmo, is a steroidal ester, androgen antagonist derived from 11-deoxycortisone, which tightly mimics the profile of an ideal anti-androgen for topical use.

    The objective is to create a product for topical application to treat acne, male pattern baldness, and seborrhoea that does not have the side effects of products currently being taken in tablet form.

    An IND was filed in the US for CB-03-01 for acne. Clinical trials are planned to start in the USA in Q2 2012.
    http://www.cosmopharmaceuticals.com/...peline/cb.aspx

    http://www.bloomberg.com/apps/news?p...d=apTE0BEalKQs

  2. #2
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    So this means they're entering phase 1 this May. So we're 8-10 years away?

  3. #3
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    No, they're entering Phase II for acne. The alopecia product is about 12 months behind the acne product from the look of their presentations.

    As I already said in the post you must have read because you replied to it, "3 years for the acne treatment was the original prognosis, 4 years (ie 2016) for MPB."

    The licensing news is a big positive because whoever this big pharma company is, they will have deep pockets so development shouldn't stall through lack of funds.

    And it's not a growth stimulant, it's an anti-androgen. But in the POC study it showed regrowth that I'd say is better than Propecia. Which is not surprising, Propecia only lowers scalp DHT by something like 30% if I recall correctly. This stuff should comfortably beat that figure, while still leaving our serum DHT where it should be!

  4. #4
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    Quote Originally Posted by Pate View Post
    No, they're entering Phase II for acne. The alopecia product is about 12 months behind the acne product from the look of their presentations.

    As I already said in the post you must have read because you replied to it, "3 years for the acne treatment was the original prognosis, 4 years (ie 2016) for MPB."

    The licensing news is a big positive because whoever this big pharma company is, they will have deep pockets so development shouldn't stall through lack of funds.

    And it's not a growth stimulant, it's an anti-androgen. But in the POC study it showed regrowth that I'd say is better than Propecia. Which is not surprising, Propecia only lowers scalp DHT by something like 30% if I recall correctly. This stuff should comfortably beat that figure, while still leaving our serum DHT where it should be!
    Here's hoping. And not just for MPB, but for acne too, in my case atleast .

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