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07-25-2012 06:15 AM
#1821
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07-25-2012 06:29 AM
#1822
Originally Posted by UK_
But as you say it probably won't be required because when a hair from donor is transplanted into slick bald the surrounding tissue thickens and behaves as it did when there was hair there before, so by planting cells the body will know what to do which is why replicel had successful phase 1.
i guess we can only hope. We will know more when they do further trials.
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07-25-2012 06:41 AM
#1823
This study conducted earlier this year shows that DP cells (NOT DSC CELLS) when transplanted through cell therapy work very well with heightened wnt signalling through GSK-3β inhibition, I wonder if Intercytex did it this way?....
The real treatment will come as a combination of the best possibilities:
Abstract:
It is well known that dermal papilla cells (DPCs) play crucial roles in hair follicle induction. In this study, we examined whether Wnt/β-catenin activation results in maintenance of the hair-inducing ability of human DPCs. Expression of DPC marker genes was maintained under Wnt/β-catenin signalling stimulation by GSK-3β inhibition. Furthermore, human DPCs showed constant hair induction when transplanted with murine epidermal cell fraction. Alu-positive human DPCs were essentially detected adjacent to the reconstructing epidermal structure positive for P-cadherin immunoreactivity. The transplanted human DPCs were abundant in the surrounding dermal sheath portion of the fully regenerated hair follicles. These results support the importance of Wnt/β-catenin signalling in hair follicle induction. This study may provide valuable information to establish a culture method of human DPCs for cell-based therapy.
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07-25-2012 07:21 PM
#1824
Originally Posted by UK_
I just got my hair cut - **** man .
Does anyone else here have trouble looking at themselves in the mirror when getting their hair cut?
I wish I had a hair line that was 2mm above my eyebrows
fml.
Ha I feel you man. I hated it so much I learned how to cut my own hair, pretty sad, but Ive gotten pretty good at it
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07-26-2012 11:22 AM
#1825
I know I hope we get an update on when Phase 2 starts real soon.
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07-26-2012 05:45 PM
#1826
Senior Member
Originally Posted by greatjob!
Ha I feel you man. I hated it so much I learned how to cut my own hair, pretty sad, but Ive gotten pretty good at it
same, home hair cutters FTW
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07-27-2012 04:55 AM
#1827
Originally Posted by UK_
I know I hope we get an update on when Phase 2 starts real soon.
Also good as that, is having some information about 12 months results. Last patient completed his 6 months follow up on Jan 12, so we´ve reached 12month mark for all patients.
Already e-mailed them asking if they´re going to release some of this results and when.
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07-29-2012 02:40 PM
#1828
Yeah id love to see those too!
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07-31-2012 10:52 AM
#1829
Originally Posted by UK_
I just got my hair cut - **** man .
Does anyone else here have trouble looking at themselves in the mirror when getting their hair cut?
I wish I had a hair line that was 2mm above my eyebrows
fml.
Every one of us here on this forum, every single one of us!!
Just got to remember you're not the only one, does that even help? I'm not even sure of that.
So, back to thread, back to Replicel...!
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07-31-2012 06:51 PM
#1830
It is comforting to know that the person cutting my hair is also NW6.
This time next year I will be full blown NW6 at the moment I am NW 5.
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