Histogen Update - Spencer Kobren Speaks With Dr. Craig L. Ziering

[BoSox]

Been taking Fin for 5 years, 0 side effects. You'd be a fool not to take this drug, save your hair for HSC.

That aside, can we stay on the topic of Histogen please.. we have other threads for other topics.

[jpm]

According to Spencer, Dr Z has some exciting news. Hopefully he gets the interview soon.

Where did you hear Spencer say this out of interest?

I think the exciting news will be off the back of some of the things they have talked about at the recent conference. Anyone have any idea what Histogen said at the conference?

[neversaynever]

Where did you hear Spencer say this out of interest?

I think the exciting news will be off the back of some of the things they have talked about at the recent conference. Anyone have any idea what Histogen said at the conference?

I dont think people should get excited about their exciting news.

They'll probably end up saying "the big news is that it's safe, and we are seeing increased hair counts. This makes us confident that when phase 2 finishes, we should have good results".

It will be vague. Remember they are still very early into their phase 2, they are a long way from publishing results.

They've always been the biggest hope of the big 4 research groups, because they are getting results, and kept us updated. And the way they plan to release earlier in Asia is a big big plus. But I really dont see what exciting news they'll have when they're not even 6 months into phase 2.

[neversaynever]

Would be nice if spencer can ask Dr Z what he thinks of Dr Cotsarelis' findings concerning prostaglandin D.

If prostaglandin D is the bullet that shrinks our follicles (DHT being the gun?), then it should be of great interest to Histogen.

[yeahyeahyeah]

I dont think people should get excited about their exciting news.

They'll probably end up saying "the big news is that it's safe, and we are seeing increased hair counts. This makes us confident that when phase 2 finishes, we should have good results".

It will be vague. Remember they are still very early into their phase 2, they are a long way from publishing results.

They've always been the biggest hope of the big 4 research groups, because they are getting results, and kept us updated. And the way they plan to release earlier in Asia is a big big plus. But I really dont see what exciting news they'll have when they're not even 6 months into phase 2.

Any POSITIVE news is an encouraging sign that a CURE is near. It also means that histogen are on track to release a viable product. Rather that then hear nothing at all, like follica.

I don't get why people on here are SO NEGATIVE. Do you guys want a better hairloss solution or what?

[neversaynever]

Any POSITIVE news is an encouraging sign that a CURE is near. It also means that histogen are on track to release a viable product. Rather that then hear nothing at all, like follica.

I don't get why people on here are SO NEGATIVE. Do you guys want a better hairloss solution or what?

Im not negative. I believe they'll bring a product to the world, but I dont believe they'll have any big news in the next few weeks. And I really dont think histogen will provide us with a cure! I think it'll be a treatment that will bury current 'treatments'.

Unless the exciting news is that theyve found a formula of HSC that wakes up sleeping stem cells.

[tizzle]

who knows. they inject more hsc in trial no2 so its imaginable that there are even better result. Even in the early stages of the trial.

but i think is wise to keep expectations low

[BoSox]

How the f*ck can you guys be so negative about Histogen? I'm SURE their news will be exciting, they've already proven themselves in phase 1 with incredible results.


Lighten the f*ck up, seriously.

[neversaynever]

How the f*ck can you guys be so negative about Histogen? I'm SURE their news will be exciting, they've already proven themselves in phase 1 with incredible results.


Lighten the f*ck up, seriously.

Noones being negative. How can they provide such amazing news so early into their phase 2 trial? Is that so hard to understand?

Eventually sure, but there is still alot of time.

[BoSox]

Noones being negative. How can they provide such amazing news so early into their phase 2 trial? Is that so hard to understand?

Eventually sure, but there is still alot of time.

They said that got positive news to report, let's just leave it at that. From what I've already heard and seen from Histogen, any additional good news is something to be excited about.

I guess we'll see exactly what

[jpm]

They said that got positive news to report, let's just leave it at that. From what I've already heard and seen from Histogen, any additional good news is something to be excited about.

I guess we'll see exactly what

I agree. Histogen are already very exciting in the progress they have made and the potential to produce a very good treatment. Therefore any other exciting news, no matter how small, is a bonus.

By the way, everyone who says that at 3 months its too early to have any news. At 3 months during the Phase 1/2 trial, 16% regrowth had already been seen!!

[neversaynever]

I agree. Histogen are already very exciting in the progress they have made and the potential to produce a very good treatment. Therefore any other exciting news, no matter how small, is a bonus.

By the way, everyone who says that at 3 months its too early to have any news. At 3 months during the Phase 1/2 trial, 16% regrowth had already been seen!!

I get confused with the histogen % figures. Is that 16% average across all patients or just the highest figure at that point?

[2020]

There is no reason to be negative at this point.... They're not cloning cells or anything, their procedure isn't nearly as complicated compared to other guys. As long as their stuff doesn't grow tumors at high doses, everything else will work out

[gmonasco]

How does Histogen come up with hair count figures like 126.5? What constitutes half a hair? Is there some kind of averaging procedure involved in the hair count process?

[2020]

I get confused with the histogen % figures. Is that 16% average across all patients or just the highest figure at that point?

dude.... it's all on the first page of their site:

http://jddonline.com/articles/dermatology/1650

At the initial 12-week evaluation period, HSC-treated sites demonstrated an increase in hair shaft thickness (6.3% ± 2.5% vs. -0.63% ± 2.1%; P=0.046), thickness density (12.8% ± 4.5% vs. -0.2% ± 2.9%; P=0.028), and terminal hair density (20.6 ± 4.9% vs. 4.4 ± 4.9%; P=0.029).

terminal hair density: average was 20.6% with some subjects getting as much as ~25% and as low as ~16%