Histogen Update - Spencer Kobren Speaks With Dr. Craig L. Ziering

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  • Follicle Death Row
    Senior Member
    • May 2011
    • 1066

    Dr. Cole is a good guy but I'm not sure if his Aderans argument is sound. To be fair, hair system/piece/wigs sales, whatever you want to call them, have been declining for well over ages. I think it makes sense for Aderans to invest in HM now rather than do nothing and see their business collapse. Very shrewd business move I'd say.

    I'll have to have a look at the Aderans timeline I put up somewhere to see when they're supposed to go into phase 3. I'd imagine it must be Q1 or 2 of 2012. They're testing I think 4 different methods of the cultured/multiplied dermal papillae as far as I am aware.

    Comment

    • Follicle Death Row
      Senior Member
      • May 2011
      • 1066

      Originally posted by Jundam
      Yeah. All it takes is for one of them to hit phase III with promise and it'll be covered worldwide by every spectrum of the media. Nobody's going to miss it.
      Might look into buying some stock then.

      Comment

      • Follicle Death Row
        Senior Member
        • May 2011
        • 1066

        Also by the logic I think Aderans are following, it would be in Dr. Cole's interest to keep an eye on this stuff and look to provide it unless he plans on retiring within in the next decade.

        Comment

        • Dasani
          Member
          • Jun 2011
          • 57

          Originally posted by Follicle Death Row
          That definitely sounds promising Dasani. Cheers for that. I wonder does the average young bald guy out there know anything about the likes of Histogen, Aderans, Follica and Replicel? What I mean to say is, is it just a select few, (us mainly, TBT regulars), that are pinning our hopes on these future treatments or is it common knowledge to your average bald guy that this stuff is in trials. It's kind of not socially acceptable to discuss baldness (in my country at least) and it is seen largely as a trivial issue (but I think it's changing) so you never really know what the general public is thinking regarding all this.

          I happen to think the fact all these companies are well into trials is a big deal but are we just overly optimistic on all this? I'm genuinely excited about the results coming in Q1 2012. Aderans, Histogen and Replicel are all due to weigh in with their findings. What interests me is the fact that we have two similar procedures in what Aderans and Replicel are doing yet one is going through the FDA whereas the other is taking the line that the whole procedure is autologous and therefore that circumvents the need to go through traditional FDA trials. Are we genuinely looking at Aderans getting Ji Gami out in 2014 in the US and Replicel coming out somewhere in 2014 along with Histogen?

          If we knew these timelines were realistic we could rest a little easier. If it was guaranteed that these treatments could give you 50FU/cm2 all over by 2016 I would be very content to wait. Would definitely put my mind at rest.
          Yes I agree. No way to tell how good these treatments are going to be, but the people producing them have offered up 2014/2015 as tentative release dates. We're just going to have to wait until January/Feb/March of 2012 to see the clinical trial results. I HOPE they blow everything else out of the water.

          Comment

          • Losing_It
            Member
            • Jun 2011
            • 89

            Idk maybe Dr. Cole's criticism is valid, he is after all an insider to the Industry so maybe a little bird whispered something in his ear. What is up with Follica though, they are like the CIA of the hair loss industry.

            Comment

            • Jundam
              Senior Member
              • Mar 2011
              • 110

              A hypocritical "insider" with everything to lose and nothing to gain from the potential success of the scientific progress he's talking shit about.
              I give his opinion absolutely no credit.

              As far as Follica goes it's anybody's guess. Everything you hear about them seems to be founded on rumors.

              Comment

              • Dasani
                Member
                • Jun 2011
                • 57

                So who in this thread is obsessed with the potential for a cure besides me? I'm 23, and I just recently noticed I was starting to get thin in my crown. I was shocked because I had never thought about hair loss and I just didn't think about it as something that happens to people in their early 20's. So I freaked out, but immediately got on Finasteride and Minoxidil after a quick visit to the dermatologist. ~2.5-3 months later... my hair has had very good results. It's gotten much thicker and I really can't see any thinning in my crown.

                So now if this was 1992 I'd still consider myself screwed and just delaying the inevitable. However today, there's hope for potentially 'curing' baldness in the near future. I'd say (based on clinical trail results for finasteride and minox + my results so far + plan guesswork) I have anywhere from 5-7 maybe 8 years before the effects of my treatments start wearing off. Histogen has said it's product could be available as early as 2014 in certain countries (~2.5 years away). Aderans has also said 2014. Replicel, who knows but I can't image it being significantly longer.

                Needless to say I'm white-nuckling it and just plain hoping these potential future treatments actually pan out.

                Comment

                • stillinHS1994
                  Member
                  • Jul 2011
                  • 72

                  Ummmm all of us? I think its safe to say all of us are obsessed with a potential cure...I know I am

                  Comment

                  • Jundam
                    Senior Member
                    • Mar 2011
                    • 110

                    I'm not really obsessed, I'm just intrigued by the possibility. It's one of the few fields of research that I have a personal interest in so it gets some extra attention during downtime. I still have a pretty full head of hair thanks to Propecia and Rogaine but I'm currently shaving it all off with a razor every few days and I kind of like it. My problem with it, and the reason I'm hoping for a cure, is because this look requires shaving essentially every day/every other day. I'd prefer just getting a haircut every 3 months like I used to. To some extent I'd also prefer to have the choice of going between shaved and long hair, rather than being forced into one for the rest of my life. I'm 23 now and my hope is that when I'm somewhere between 30-35 there'll be a solution for me. Although sooner works too. Since I started balding at 19 and looking my father's pattern I'm gonna be a Norwood 6 so hair transplants are out of the question due to limited donor.

                    Comment

                    • Samiam
                      Senior Member
                      • Apr 2011
                      • 268

                      Originally posted by Dasani
                      So who in this thread is obsessed with the potential for a cure besides me? I'm 23, and I just recently noticed I was starting to get thin in my crown. I was shocked because I had never thought about hair loss and I just didn't think about it as something that happens to people in their early 20's. So I freaked out, but immediately got on Finasteride and Minoxidil after a quick visit to the dermatologist. ~2.5-3 months later... my hair has had very good results. It's gotten much thicker and I really can't see any thinning in my crown.

                      So now if this was 1992 I'd still consider myself screwed and just delaying the inevitable. However today, there's hope for potentially 'curing' baldness in the near future. I'd say (based on clinical trail results for finasteride and minox + my results so far + plan guesswork) I have anywhere from 5-7 maybe 8 years before the effects of my treatments start wearing off. Histogen has said it's product could be available as early as 2014 in certain countries (~2.5 years away). Aderans has also said 2014. Replicel, who knows but I can't image it being significantly longer.

                      Needless to say I'm white-nuckling it and just plain hoping these potential future treatments actually pan out.


                      Dude if your treatments are working right now than relax a bit.

                      Comment

                      • Follicle Death Row
                        Senior Member
                        • May 2011
                        • 1066

                        Originally posted by Dasani
                        So who in this thread is obsessed with the potential for a cure besides me? I'm 23, and I just recently noticed I was starting to get thin in my crown. I was shocked because I had never thought about hair loss and I just didn't think about it as something that happens to people in their early 20's. So I freaked out, but immediately got on Finasteride and Minoxidil after a quick visit to the dermatologist. ~2.5-3 months later... my hair has had very good results. It's gotten much thicker and I really can't see any thinning in my crown.

                        So now if this was 1992 I'd still consider myself screwed and just delaying the inevitable. However today, there's hope for potentially 'curing' baldness in the near future. I'd say (based on clinical trail results for finasteride and minox + my results so far + plan guesswork) I have anywhere from 5-7 maybe 8 years before the effects of my treatments start wearing off. Histogen has said it's product could be available as early as 2014 in certain countries (~2.5 years away). Aderans has also said 2014. Replicel, who knows but I can't image it being significantly longer.

                        Needless to say I'm white-nuckling it and just plain hoping these potential future treatments actually pan out.
                        I think you'll make it to follicle escape velocity. You could well keep your hair. I'm not so confident of my own prospects (I'm not on fin). The treatments of the future will have to be able to give me some hair back.

                        Comment

                        • Follicle Death Row
                          Senior Member
                          • May 2011
                          • 1066

                          Originally posted by Jundam
                          I'm not really obsessed, I'm just intrigued by the possibility. It's one of the few fields of research that I have a personal interest in so it gets some extra attention during downtime. I still have a pretty full head of hair thanks to Propecia and Rogaine but I'm currently shaving it all off with a razor every few days and I kind of like it. My problem with it, and the reason I'm hoping for a cure, is because this look requires shaving essentially every day/every other day. I'd prefer just getting a haircut every 3 months like I used to. To some extent I'd also prefer to have the choice of going between shaved and long hair, rather than being forced into one for the rest of my life. I'm 23 now and my hope is that when I'm somewhere between 30-35 there'll be a solution for me. Although sooner works too. Since I started balding at 19 and looking my father's pattern I'm gonna be a Norwood 6 so hair transplants are out of the question due to limited donor.
                          I'm facing a similar scenario. I'm 25 now and would be happy enough if these treatments came along by 33ish. It would be nice to get back a full head of hair before time catches up and the rest of the body goes to shit anyway and you wonder why you were ever bothered by hair loss in the first place. It's ****ing horrible losing your hair in your early 20s. It's certainly not average or normal (based on people I know anyway). Of course things could be a lot worse but I still feel a little bitter because I feel cheated a bit and it's not par for the course. Think it would be fair enough if the hair started the balding process at 35 like it did for my old man (ok well I haven't been cheated since it's in the genes but why so young?). Kind of seems fairer when you're approaching early-middle age and it's more in sync with the rest of the changes your body undergoes. I suppose it's just tough because it does feel like you've been robbed of some of your youth to an extent.

                          I think if I make it to 35-40 and there's no cure it won't really be an issue anymore. I'd be like sod it, bit late now. I know people will always care about their appearance no matter what age they are but I think not having hair at 35 or 40 has a lot less of an impact on your self image and on how others perceive you than if you were in your early 20s. It's about what's normal, for me at least. Kind of sucks when you're young and everyone else is rocking a full head of hair.

                          Comment

                          • Sogeking
                            Senior Member
                            • Feb 2011
                            • 497

                            @Follicle Death Row
                            Hey Follicle I think there are a few reasons why I going bald before the 35-40 time interval sucks more, although it is not a pleasant affliction at any age:

                            1. You are young so you are still in the hunting mode for young women since your testosterone level is higher, having hair increases the odds.

                            2. By the age of 35-40 I expected to be married with hopefully a good wife which wouldn't be bothered by my hair loss. In that case hair loss would be less of a nuisance. For the most part having hair is about getting chicks. I don't care much about what guys think of me if I am bald. No offense guys.

                            3. At the age of 23 when my hair started to thin, I was and I still am a student. I have no money for anything expect the basic needs in life that are provided by my parents. If I were at a later age I might even have money to try new treatments maybe even afford Rogaine foam on a regular basis.
                            If a new treatment arrives I wouldn't have money for it.

                            Hair loss sucks at any age but especially at younger ages.
                            However I still believe there are worse fates than hair loss.

                            Comment

                            • CVAZBAR
                              Senior Member
                              • Dec 2010
                              • 444

                              Yes the biggest problem for me is accepting baldness at a young age. Still have some hair and almost hitting 30 but still. But maybe we should look at it, the way Spencer put it. "This is the best time ever to go bald". We might be saved in the near future guys.

                              Comment

                              • Jundam
                                Senior Member
                                • Mar 2011
                                • 110

                                Well, actually the best time ever to go bald would be when an effective hair loss treatment is already on the market because then you'd never have to worry about anything but the potential expenses.

                                The bitch about going bald now is the uncertainty. There is hope but there is no confirmation of it being justified. If Replicel or Histogen comes through in clinical trials and shows an ability to effectively cure our condition I won't really care if I have to wait till 2014-2016. There really won't be anybody in this world appreciating their hair as much as the formerly bald.

                                Comment

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