Histogen Update - Spencer Kobren Speaks With Dr. Craig L. Ziering
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Yeah, I'm gonna pass on the explanation. I think I've got a handle on all you're gonna say. Good luck on your exams, though!Comment
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You are saying a lot more than that - and you are reading more into what others are saying than they are actually saying. Next thing you know you will claim I said it's better to let it go slick bald - which would be a complete lie. There is no way I would ever say that.Comment
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I think both Histogen and Replicel are on two different paths to a better solution - both correct paths. Though Histogen's treatment won't be a true cure, I do believe it will be a significantly better treatment than those currently available. Replicel is on the way to a true cure though. I can easily envision these two treatments being used together to achieve both the goals of restoring a full head of hair (Histogen) and preventing future hair loss (Replicel). Time will tell.Comment
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I think both Histogen and Replicel are on two different paths to a better solution - both correct paths. Though Histogen's treatment won't be a true cure, I do believe it will be a significantly better treatment than those currently available. Replicel is on the way to a true cure though. I can easily envision these two treatments being used together to achieve both the goals of restoring a full head of hair (Histogen) and preventing future hair loss (Replicel). Time will tell.Comment
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I think both Histogen and Replicel are on two different paths to a better solution - both correct paths. Though Histogen's treatment won't be a true cure, I do believe it will be a significantly better treatment than those currently available. Replicel is on the way to a true cure though. I can easily envision these two treatments being used together to achieve both the goals of restoring a full head of hair (Histogen) and preventing future hair loss (Replicel). Time will tell.
Anyway, some interesting results published by Histogen. It's nice to see pictures which show substantial hair regrowth for once. The part about it being compoundable is also very promising.
Nevertheless, we've also seen comparable pictures for known snake oils. So until I see more pictures like these for balding men, I won't get too optimistic. Definitely warrants another interview and renewed attention however.Comment
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Did you read the post above yours?
Yes, I do undertand the science involved a little more than the average person. Another person asked for my opinion and I gave it. I am entitled to have an opinion - and I am entitled to give that opinion if someone asks for it, even if it isn't popular think positive around here.Comment
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Did you read the post above yours?
Yes, I do undertand the science involved a little more than the average person. Another person asked for my opinion and I gave it. I am entitled to have an opinion - and I am entitled to give that opinion if someone asks for it, even if it isn't popular think positive around here.Comment
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I hope that everyone is clear on the fact that when they state that there was a 50% or whatever it was increase from the baseline count at 3 months, that they don't mean a 50% increase of what a full head of hair is, they mean a 50% increase in the hair that was presently there.
Thus, if one if these pictures from Histogen says it had a 60% increase in an area where there was only 20% of their original hair, that really the hsc only made them have an increase of around 10% from what their full head of hair would be. anyone following me here??? maybe im stupid and you all already know this....Comment
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So when will this be available in Asia? It would help with the funding for next phase trials.
We need another interview Spencer...
Questions
Did HST work to some degree on all patients?
What were the norward scales of the male patients being treated and was it tested in slick bald areas?
How are the 24 patients from the pilot study, is there hair continuing to grow and is DHT having any effect on the hair they have grown and there existing hair?
Has it been tested in areas of transplanted hair?
Release in Asia 2013
Love your work SpencerComment
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let's be a realistic here. this result was for women who have low DHT, mild and recent hair loss.
won't grow hair in bald scalps that have been bald for years.
By the time this comes out we will be a nw7. You need to maintain to get some results that may not even happen because we don't know the results on MAN.
I achieved this same result but had to drop minox because of sides.
In resume all this is: a minoxidil on steroids.
Still helpful and you don't have to apply daily.
And there have been results in men, even more so in phase I/II than in the pilot study. Who knows, if Replicel can improve their results, maybe a combination of Histogen and Replicel can regrow hair in a bald scalp.
And this is much more than "minoxidil on steroids." Histogen and Minoxidil shouldn't even be used in the same sentence. Histogen actually turns miniaturized follicles back to terminal - minoxidil does no such thing. In fact, I'm inclined to believe that minoxidil doesn't actually do shit for your follicles - the only reason it makes your hair appear thicker is that it gets all the follicles on the same "schedule" so that they're all breaking the scalp surface at the same time, creating the appearance of more hair. And it may possibly lengthen the anagen phase. But i don't think it actually helps the follicles at all.Comment
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I hope that everyone is clear on the fact that when they state that there was a 50% or whatever it was increase from the baseline count at 3 months, that they don't mean a 50% increase of what a full head of hair is, they mean a 50% increase in the hair that was presently there.
Thus, if one if these pictures from Histogen says it had a 60% increase in an area where there was only 20% of their original hair, that really the hsc only made them have an increase of around 10% from what their full head of hair would be. anyone following me here??? maybe im stupid and you all already know this....
lets assume HSC revitalizes shrunken hair follicles :
1. Early stage of MPB where 50% of the follicles are out of business (Shrunk) and 50% are perfectly active
-->50% increase from baseline means you end up with 75% hair (of your original state before MPB) and therefore lets say HSC will have a succes rate of 50% on shrunken follicles (The other 50% lets say are gone period)
2. Progressed stage of MBP where only 20% of the follicles are still perfectly active
--> of the 80% inactive, HSC will "wake up" half of them (Ergo 40%) so in the end you will jump from 20% to 60% of your original state before MBP (in comparison to example 1 where you only jump from 50% to 75%.
This is all hypothetical. I just wanted to show that only because you compare trial results to haircount from baseline does not mean that if you are completely bald, that you will not get back some hair from HSC
It all depends on how HSC works exactly (We dont know), how it will effect shrunken follicles (We dont know) and if it does anything to follicles that so many here call "dead" (we dont know)
But i cant wait for further resuults. Histogen has done so extremely well, im sure they will even make HSC more effective than it is now in the next stages of the trialsComment
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