Histogen Update - Spencer Kobren Speaks With Dr. Craig L. Ziering

[cannonball]

For visualization purposes, I went around looking a common household objects to find something that is about the same size as the test area. 2 square millimeters is roughly the size of the diameter of a grounding pin on a 3-prong electrical plug in the United States. If you don't know what that is, here is a photo.

http://www.raygirling.com/ryobi/images/fig01.gif

In that area, 25 new hairs were seen at one year.

Oh, but I think its rather 2 square cm, which should be around the third of a square inch...

[KeepHoping]

I think that part of the plug would be one sqare centimeter right?

[Purple Glow]

I think that part of the plug would be one sqare centimeter right?

No, here is an image of one square centimeter proportional to a pencil.
http://www.mathsisfun.com/measure/images/square-cm.jpg

As you can see, that box is much larger than a grounding pin on a 3-prong plug.

[RichardDawkins]

So then, whats the verdict here :-)

Good or Bad. But how did you guys come on 25 hairs, i heared something about 100 hairs :-)

[gmonasco]

I think all the speculation about hair counts is moot until we know:

1) That HSC is actually producing new hairs (rather than merely coaxing existing hairs out of the telogen phase).

2) Whether the effect is compoundable with larger or repeated dosages.

[Purple Glow]

So then, whats the verdict here :-)

Good or Bad. But how did you guys come on 25 hairs, i heared something about 100 hairs :-)

I got 25 hairs from a direct quote from Dr. Z that I quoted in post #193 of this thread.

[mlao]

I think all the speculation about hair counts is moot until we know:

1) That HSC is actually producing new hairs (rather than merely coaxing existing hairs out of the telogen phase).

2) Whether the effect is compoundable with larger or repeated dosages.

Thumbs up to this statement!

[UK_]

I got 25 hairs from a direct quote from Dr. Z that I quoted in post #193 of this thread.

Was it not 84.5 hairs after 12 months? This in an area of 1.46cm2 I believe.

Found this on their website:

Histogen named a Top 300 Startup by fundedIDEAS for 2011! Company successfully completes Series A financing round, and opens Series B, with Phase I / II trial beginning this Spring.

http://www.fundedideas.com/index.html

Congratulations guys!

[CAlex]

Yes UK you are basically correct. an increase of about 84 hairs in a 1.47 cm/2 area was the result in phase 1.

179 hairs baseline to 263 hairs after 1 year. It was basically a 47% increase in new hairs but the studied posted a 70 plus % increase because histogen took into account existing hairs increase in thickness etc.

The only thing in terms of percentages and numbers we need to take from phase 1 is that there was a good result from a SAFETY trial and this method holds much promise.
Phase II will include much more patients in the study with more emphasis on dosages and frequency of shots etc.

Phase II numbers will definitely be much more meaningful even if they still produce only the same hair increase as phase 1. It will show the ability to reproduce the results over a much more extensive patient base and recipient area.

[CVAZBAR]

For visualization purposes, I went around looking a common household objects to find something that is about the same size as the test area. 2 square millimeters is roughly the size of the diameter of a grounding pin on a 3-prong electrical plug in the United States. If you don't know what that is, here is a photo.

http://www.raygirling.com/ryobi/images/fig01.gif

In that area, 25 new hairs were seen at one year.

Excellent idea Purp.