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05-09-2012 08:47 AM
#1521
Senior Member
Originally Posted by Pate
They did say that average regrowth at 12 months was 25 hairs per injection. I think in most cases that would be about a 15% increase in total hair count.
15% after 12 months? Where are you getting this? Even after 3 months, the hair count jumped 20%+ on average.
That 73% was the maximum result they were able to achieve at 12 months with a small injection.
Things are looking good with Histogen. As long as this stuff doesn't grow tumors at high doses, we're good
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05-09-2012 09:18 AM
#1522
we should stop throwing all these numbers. its confusing
i think we should wait until this second study is over
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05-09-2012 10:42 AM
#1523
I think the numbers and info are a bit too vague at this point. Sure, max 73% increase, but in one patient, in an area that had plenty of hairs already.
The bigger issue are areas of scalps with invisible hairs.
Im also curious of what they think about Dr Cots prostaglandin D synthase finding.
"The inhibition of hair growth is triggered when the protein binds to a receptor on the cells of hair follicles, said Prof Cotsarelis"
Personally, I believe that is the most specific info we've had for a long time. I wonder how HSC deals with that....
Besides, havent they only elapsed 3 months of 2 years? Phase 2 is two years right? And then phase 3 is 2 years....no?
Correct me if im wrong, which i hope is the case
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05-09-2012 11:44 PM
#1524
If anyone knows what Histogen says at this conference that is currently going on, can they please post
Thanks
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05-10-2012 04:35 AM
#1525
Originally Posted by 2020
15% after 12 months? Where are you getting this? Even after 3 months, the hair count jumped 20%+ on average.
That 73% was the maximum result they were able to achieve at 12 months with a small injection.
Things are looking good with Histogen. As long as this stuff doesn't grow tumors at high doses, we're good
No, 20% was the increase in terminal hair count, which has always been higher than the increase in total hair. The chart on the website, which appears to show the average of the trials, has a 15% increase in total hair count at 12 months.
And no, 123% was the maximum increase in terminal hair achieved at 12 months. The 73% figure was their second best.
25 hairs per sq
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05-10-2012 05:05 AM
#1526
Originally Posted by neversaynever
I think the numbers and info are a bit too vague at this point. Sure, max 73% increase, but in one patient, in an area that had plenty of hairs already.
The bigger issue are areas of scalps with invisible hairs.
Im also curious of what they think about Dr Cots prostaglandin D synthase finding.
"The inhibition of hair growth is triggered when the protein binds to a receptor on the cells of hair follicles, said Prof Cotsarelis"
Personally, I believe that is the most specific info we've had for a long time. I wonder how HSC deals with that....
Besides, havent they only elapsed 3 months of 2 years? Phase 2 is two years right? And then phase 3 is 2 years....no?
Correct me if im wrong, which i hope is the case
I'd rather vague from Histogen over shite from RepliCel :P
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05-10-2012 05:05 AM
#1527
Originally Posted by jpm
If anyone knows what Histogen says at this conference that is currently going on, can they please post
Thanks
Whats the link to the conference site?
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05-10-2012 05:29 AM
#1528
Okay, so. In order to stop these figures flying back and forth all over BTT and the other forums... I have bought the Histogen paper published in the JDD and linked to on their website. Cost 15 USD for a one-time purchase. Unfortunately I am not a student any more I would have free access to journals like these through my university but oh well, 15 USD is a small price to pay.
So here are the official figures from Histogen, published in the peer-reviewed journal.
At 3 months:
Shaft thickness +6%
Thickness density +13%
Terminal hair count +21%
No mention of total hair count, presumably it was not statistically significant
At 5 months:
No statistically significant increase over 3 months (obviously some individuals had better results at 5 months but the overall change was not statistically significant).
At 12 months:
Total hair count +16%
Thickness density +18%
Terminal hair count +30%
So there you have it, straight from the source. A single injection of HSC resulted in an average 30% increase in terminal hair count at 12 months. There is some other interesting stuff in the paper too but I haven't read it all yet.
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05-10-2012 05:39 AM
#1529
Originally Posted by Pate
Okay, so. In order to stop these figures flying back and forth all over BTT and the other forums... I have bought the Histogen paper published in the JDD and linked to on their website. Cost 15 USD for a one-time purchase. Unfortunately I am not a student any more I would have free access to journals like these through my university but oh well, 15 USD is a small price to pay.
So here are the official figures from Histogen, published in the peer-reviewed journal.
At 3 months:
Shaft thickness +6%
Thickness density +13%
Terminal hair count +21%
No mention of total hair count, presumably it was not statistically significant
At 5 months:
No statistically significant increase over 3 months (obviously some individuals had better results at 5 months but the overall change was not statistically significant).
At 12 months:
Total hair count +16%
Thickness density +18%
Terminal hair count +30%
So there you have it, straight from the source. A single injection of HSC resulted in an average 30% increase in terminal hair count at 12 months. There is some other interesting stuff in the paper too but I haven't read it all yet.
Nice find. Can't wait for their next update!!
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05-10-2012 05:42 AM
#1530
Originally Posted by Pate
Okay, so. In order to stop these figures flying back and forth all over BTT and the other forums... I have bought the Histogen paper published in the JDD and linked to on their website. Cost 15 USD for a one-time purchase. Unfortunately I am not a student any more I would have free access to journals like these through my university but oh well, 15 USD is a small price to pay.
So here are the official figures from Histogen, published in the peer-reviewed journal.
At 3 months:
Shaft thickness +6%
Thickness density +13%
Terminal hair count +21%
No mention of total hair count, presumably it was not statistically significant
At 5 months:
No statistically significant increase over 3 months (obviously some individuals had better results at 5 months but the overall change was not statistically significant).
At 12 months:
Total hair count +16%
Thickness density +18%
Terminal hair count +30%
So there you have it, straight from the source. A single injection of HSC resulted in an average 30% increase in terminal hair count at 12 months. There is some other interesting stuff in the paper too but I haven't read it all yet.
it takes 1 year for significant results to grow hair , which is the reason why replicel's 6 months results perceived as failure , probably they will also get good results after 6 months
but histogen is far ahead , 30% is excellent , hope they offer it soon
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