Histogen Update - Spencer Kobren Speaks With Dr. Craig L. Ziering
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And I don't think I'm a lost cause for HSC yet (my hairline probably is though). We just don't have enough info yet on how it'll work on more advanced miniaturisation. It may be that it still works but needs more injections, or higher concentrations, or takes longer to respond.
Just hang on to what you've got as much as possible. If gmonasco's interpretation is right then we higher Norwoods will need all the help we can get.Comment
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I think that as long as you haven't been slick bald for years then its going to help you.
As for hair - some people have had results using Minoxidil on their hairline, so if this is only Minoxidil 'on steroids' then it maybe to help at the hairline. That near invisible peach fuzz could turn terminal!
I'm taking no chances, gonna stay on fin to maintain until its releasedComment
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I found this Q&A on another forum, it might awsner a few questions you guys have. Turns out HSC will work on all forms of hair loss, and transplanted areas.
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Dr Craig L. Ziering (Histogen’s principal clinical investigator) answered to some questions from users on the ************* forum back in February:
Q. Do you think a person who’s approaching a Norwood 5 or 6 can be helped with Histogen?
A. It has the potential to treat all stages of hairloss.
http://www.*************.com/showpost.p ... stcount=25
Q. Will having a hair transplant now will interfere with having Histogen injections in the future?
A. No , having a transplant now will not prevent you from receiving HSC injections in the future. The great thing is that HSC works on the recipient area and has nothing to do with the donor at this time . This should give new hope to all those that have poor or no donor hair available.
http://www.*************.com/showpost.p ... stcount=15
Q. Aside from Singapore I haven`t heard of any other countries in Asia taking part in the trials. Which, if any, other countries are going to take part in the trials? Thanks.
A. Right now Singapore but possibly Korea as well.
http://www.*************.com/showpost.p ... stcount=16
Q. I got an email from gail naugton last month saying "We are starting phase 1/2 in Singapore before the end of May and hope to have phase 3 pan-Asian data by Sept 2012 for an NDA submission and 2013 approval. (hopefull Q2 2013)."
Is it possible that the NDA submissions could be shortened? Does it have to be 6-12 months long?
Is it possible to lobby the Singapore Health Authority to shorten it?
A. Sorry , but I dont see this time frame being shortened.
http://www.*************.com/showpost.p ... stcount=27
Q. Are the new hairs from the HSC injections colored hair, for a person with greying hair?
For example if a person has white hair (ie anderson cooper) will the new grown hairs from HSC injections be white or black?
A. The hair would likely take on its original darker color.
http://www.*************.com/showpost.p ... stcount=30
Q. 1. It has not become clear to me what exactly are the results 2 years after one single injection. I can see pictures on the Histogen website which show the hair growth after 12 weeks, 5 month and 12 month. As i can see in the statistics below the the pictures, after 12 month there is still new and thicker hair growing. Now after 2 years, is there still an increase in numbers of hair and hair thickness? I mean compared to the 1 year update, are there now more and thicker Hairs? Or were the 1 year results just lasting for one more year?
2. Will there be an update on the Histogen website which shows macrophotos and statistics regarding the 2 year results?
A. The Histogen study was originally a safety study with 12 mos follow up, with efficacy as a secondary endpoint. The Company was able to modify the clinical protocol to add a two year safety endpoint but couldn't perform the full efficacy study. Photos were taken of the treatment site which indicate persistence of hair at the treatment site but an accurate hair number and thickness assessment can not be done. The scientists at Histogen believe that the new hairs seen at 1 year are a result of stimulating stem cells in the scalp and in existing normal and miniaturizing follicles to grow new hairs. There is no reason to believe that additional hairs would be stimulated after one year with only one injection at baseline. That being said, the fact that new hairs continue to grow over the one year period is quite remarkable and unprecedented in the hair growth field.
Histogen is performing exploratory case studies in Asia where patients are receiving 50+ injections at base line to assess hair growth over time. The Company hopes to have initial results from the first case studies in the next four weeks and plans on sharing those with the hair transplant community.
http://www.*************.com/showpost.p ... stcount=70
date Feb 2011
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OF COURSE it will work at all stages of hair loss! Why would it matter?
The only reason why they're not yet testing it on a bald scalp is because they know that the results would be minimal with one injection so they won't even bother "wasting" subjects just for that.....
if it grew 50 new hairs on a bald scalp, you can't really show that to your investors and say "hey look at that growth! can I have $20 million for my next phase?" So that's why they're currently targeting "hairy" areas because that's what makes their charts and graphs look goodComment
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Doesn't anyone remember this study?
But the new study shows that bald people have the same number of stem cells as those with hair. So if scientists could coax the stem cells into producing more hair follicle progenitor cells, then it would be possible to generate bigger hair follicles that could grow hair, he said.Comment
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Knowledgeable, positive, but realistic. You're an endangered species, I think.Comment
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that study is bullshit. Yes the stem cells may be there, but there are more structures that have been ravaged by MPB. Histogen won't bring all of them back.
It's better to stick with "keep as many follicles in shape as you can" than "just go slick bald the stem cells are still there so you will benefit too".Comment
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I'm sorry but you are just not paying attention... I don't know why so many of you insist that none of these future treatments will be able to help a slick bald scalp. None of you actually know that. None of you actually know anything at all - yet ya'll insist on perpetuating this nonsense. This is completely non-productive and yes it is nonsense. Until it has been shown in legitimate studies, it is nonsense. Ya'll are doing far more harm than good when you speculate in such a negative way. Sure it will likely take longer - but that does not mean they won't be able to do it. Time will tell - not speculation. Hold your horses until the real data about this is known.Comment
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I'm sorry but you are just not paying attention... I don't know why so many of you insist that none of these future treatments will be able to help a slick bald scalp. None of you actually know that. None of you actually know anything at all - yet ya'll insist on perpetuating this nonsense. This is completely non-productive and yes it is nonsense. Until it has been shown in legitimate studies, it is nonsense. Ya'll are doing far more harm than good when you speculate in such a negative way. Sure it will likely take longer - but that does not mean they won't be able to do it. Time will tell - not speculation. Hold your horses until the real data about this is known.
All these clinical trials have always been on moderate-early stage pattern baldness. Not a single one has shown or done results on slick bald areas, except aderans who's struggling to get anything else other than microscopic hair.
Many scientists in the past have experimented with replicel's aderan's and intercytex techniques. Intercytex and gho did use the same method as aderans/replicel and they FAILED because the results were not consistent, meaning that once the follicle has been affected for more than 5 years, it's done, no way to bring it back with HM.
Yes you can reactive the stem cells and bring all your hair back but that will happen most likely in 100 years.
It's better to be safe than sorry that's all I'm saying.
So for all with no treatment and if you wanna benefit from these ones coming up:
So just try to keep your follicles in shape, don't go slick bald. Don't take no chance, google, find the papers, research and then make your conclusions.
Don't believe internet trolls "just go slick bald, you can get the same hair since you were 18 years old with your stem cells".Comment
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that study is bullshit. Yes the stem cells may be there, but there are more structures that have been ravaged by MPB. Histogen won't bring all of them back.
It's better to stick with "keep as many follicles in shape as you can" than "just go slick bald the stem cells are still there so you will benefit too".
But on a side note, what structures are damaged, and what does "damaged" mean in that context? I've been trying to find info on that, but haven't been so luckt.Comment
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Stem cells are the precursor responsible for creating the structures that may have been damaged. That's sort of what stem cells ARE, man.
But on a side note, what structures are damaged, and what does "damaged" mean in that context? I've been trying to find info on that, but haven't been so luckt.
It's only one paper and one guy saying this, there are 1000s of others, read them all.
Just trying to save your ass, research more and don't believe me or any other troll. Make your own conclusions friend.Comment
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I hope this is released in 2013. I've been following Histogen since 2008, and it gave me so much joy knowing my hair loss might be fixed.. now that my thinning is getting worse, I might not be able to reach that goal
grrrr, please hurry HSC!
sorry, just venting.Comment
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