Capsaicin / TRPV1 hair-loss , very important !!!!!!!!!!!!!!!!!!!!!!!!!!!!!!! -
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  1. #1
    Join Date
    Oct 2015

    Exclamation Capsaicin / TRPV1 hair-loss , very important !!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!

    Hey guys I found something, 2 major studies about capsaicin / trpv1 and relation with hairloss.

    I don't clearly understand if capsaicin (activator of trpv1) causes hairloss or stops hairloss (I`m not used to english) so please help me understand.

    These are the studies :

    What does it say ? capsaicin causes hairloss or helps with hair growth ?

  2. #2
    Junior Member
    Join Date
    Mar 2017


    TOPICAL capsaicin causes hair loss by activating the TRPV1 receptors in the hair follicle, which cause the hair to enter the catagen phase.

    ORAL capsaicin causes hair growth because it is a selective antagonist of the cannaboid-1 receptor internally. The CB-1 receptor is activated not only be cannabis but by stress, and it's crucial in regulating hair growth--specifically, it inhibits it, which is why potheads have gross hair. This means that oral ORAL capsaicin is good especially for people who are losing hair partly due to stress but should help most people grow hair longer/better.

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