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Time Course of Hair Growth PRP & HBG: Carlos K. Wesley, M.D.
This man in his 20’s was not a good candidate for surgery. He was opposed to taking Propecia due to concern regarding the sexual side effects. After learning about the option of Dr. Wesley’s topical formula for hair growth, he opted to try this daily spray.
His time course of hair growth can be seen before, 7 months after, and one year after initiation of this topical treatment coupled with a platelet-rich plasma (PRP) session.
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Dr. Wesleys hair regrowth solution contains finasteride which only works because it is systemically absorbed into the blood stream. I hope the patient was made aware of this
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IAHRS Recommended Hair Transplant Surgeon
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Hi Dr. Wesley,
Thanks for the prompt and respectful response. I read thru the study you posted and I wanted to note the following (which is directly taken from their findings):
Plasma DHT was reduced by ~ 68 - 75% with the topical solution and by ~ 62 - 72% with the tablet. No relevant changes occurred for plasma testosterone with either treatment. No clinically significant adverse events occurred.
CONCLUSIONS:
A strong and similar inhibition of plasma DHT was found after 1 week of treatment with the topical and tablet finasteride ormulations, albeit finasteride plasma exposure was significantly lower with the topical than with the oral product (p < 0.0001).
So you are right that plasma levels of finasteride are less in patients using a topical formulation as compared to oral administration. However, plasma dht levels in the group that used topical finasteride is even less than the group taking oral finasteride which directly translates to the possibility of more side effects. In either case you are dropping systemic dht levels by more than 60%. The drug is obviously not working at a local level at the scalp. This is likely due to finasterides flat dose response curve.
Furthermore I don't think this is a strong study to base a medical treatment off of as the sample size of patients is only 24. I'd still feel safer using oral fin as we have multi phase fda studies with thousands of test subjects and years of data to go off of. I just really hope the patients utilizing this treatment realize that it is not side effect free and judging from the studies numbers may give even worse side effects than finasteride.
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Hi John MPB Our office certainly shares your concerns. However, as Dr. Wesley stated in his reply, our patients use our hair growth blend only once daily (not twice) whether or not it is coupled with a platelet-rich plasma (PRP) session. I have circled the systemic impact that a once-daily application showed (as opposed to the twice daily to which you are referring). Furthermore, the percentage of finasteride in our topical blend is less than the 0.25% used in this study.
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The photos do not appear to show cosmetically significant regrowth. Come on it's 2016 you can do better than this.
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Originally Posted by DD1
The photos do not appear to show cosmetically significant regrowth. Come on it's 2016 you can do better than this.
LOL you're setting yourself up for disappointments my friend.
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I have been fighting hair loss for many years so I'm very familiar with disappointment. So you think those pictures show real progress? I would like to see his entire head to see how he styles such thick hair.
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