Why do some men go bald at an older age?

[Alex23]

MPB could be completely hormonal, and hormone levels are different by person so you could look at various other differences between people and assume its those differences like diet/smoking... when really it was determined by hormone levels and AR density/distribution instead. Sometimes studies can actually reach false conclusions.
When you get older your DP cells age and are more affected by oxidative stress. Your hair also gets more and more sensitive to the same amount of androgens so balding like most other things gets worse as you age. Hamilton did a study where young and old men both injected with androgens the older men go bald much faster probably from increased AR sensitivity. The missing key we need is a CB or RU that is fully studied that can help mitigate androgen receptors, and combine that with propecia/dut and you have a solid combo to stop androgens. Neither treatment will stop 100 percent androgens on its own.

I'm on ru and dut brah

[dm90]

Age related hairloss does not occur in a pattern and is the result of senescence, which as burtandernie said are now being linked to AGA. We dont need to know every aspect of a disease to treat it effectively. Everyone talks about how complicated hairloss is, but its really not all that complicated, its a series of cellular pathways forced into dysregulation from an initial androgen stimulation. Removing the androgens will protect hair that hasnt started miniaturizing. But It is possible that once the process starts certain hairs will continue to shrink. Minoxidil, if you respond to it, forces many of the pathways back into regulation. Its almost like a miracle drug for those who those who respond to it, and go all the way with treatment.