Takahashi: Lgr5+ preserved using topical Ruxolitinib for GVHD; hair follicle recover

[noisette]

Hello guys, (As I can't post a thread on Hair Loss T, I do it here)

This is a study from Doctor Takahashi and published on April 2016. This study has been shown at BMT Tandem meetings 2016.
It's called : "Topical Ruxolitinib Protects LGR5+ Stem Cells in the Hair Follicle and Ameliorates Skin Graft-Versus-Host Disease "

I have found some pics of this event. On these pics we will see that topical Ruxolitinib promoting hair regeneration.

This topical : 0.5% Ruxolitinib ointment : Ruxolitinb dissolved in DMSO + Vaseline.

On a dermatology newspaper published on April 2016, there is a study (Alopecia Universalis) with a 0.6% Ruxolitinib Topical.
" The patient began treament with topical ruxolitinib, 0.6% cream twice daily to the scalp and eyebrows regions. After 12 weeks of treatment, the eyebrows were nearly normal and there was growth about 10% of scalp hair with numerous 5 to 10 mm darkly pigmented hairs arcuate and annular patches distributed over the entire scalp. The patient tolerated the medication without adverse effets".

Here some pics for your eyes

[pixels]

Great find! What does it mean for your average plebs like us?

[Bobbylobbyhobbythrobby]

It means waiting for at least five years while this goes through trialling where it's promised to be released to the public in just under a decade. After 6-7 years or so it will fade into obscurity because it only actually works 33.4% of the time on patients who previously shaved their head 5 weeks before the trials with garden shears in an anti clockwise direction whilst singing "I don't like Jamaica, I love her".

[Link Mahboi]

It means waiting for at least five years while this goes through trialling where it's promised to be released to the public in just under a decade. After 6-7 years or so it will fade into obscurity because it only actually works 33.4% of the time on patients who previously shaved their head 5 weeks before the trials with garden shears in an anti clockwise direction whilst singing "I don't like Jamaica, I love her".

+1

[pixels]

It means waiting for at least five years while this goes through trialling where it's promised to be released to the public in just under a decade. After 6-7 years or so it will fade into obscurity because it only actually works 33.4% of the time on patients who previously shaved their head 5 weeks before the trials with garden shears in an anti clockwise direction whilst singing "I don't like Jamaica, I love her".

Blah blah.

You do realise there are other countries outside of that religious abomination they call America.

... ones with more relaxed governments.

[Seuxin]

As always, great find Noisette !
Could be it suitable for AGA, we don't know !