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I got the following in an email from Dr. Coles office. This is good. Now if you get PRP you can ask what activates the PRP and maybe Cole seen something positive in guys study. Would be interesting if he post some study results.
Dr. Cole has developed a new method of preparing PRP for his patients. The process involves lysing the platelets to release growth factors. Most clinics either do not activate the platelets or they activate with calcium gluconate. When clinics do not activate the PRP, there is very little release of growth factors, so the results are usually absent. When calcium gluconate is used with the PRP, there is a release of growth factors, but it is less than that when thrombin is used. Unfortunately, bovine thrombin caries many risks such as an allergic reaction and infections. Dr. Cole’s technique caries no risk like those of thrombin and the concentration of growth factors is often 6 to 8 times higher than the concentration from bovine thrombin. What Dr. Cole has noted is that the percentage of hairs remaining in the active growing phase following hair transplantation is much higher when he uses his revolutionary method of lysing platelets to release the growth factors. Dr. Cole was the first in the world to combine Acell with PRP, and this new method of preparing PRP once again sets a new industry standard for the use of PRP as both a stand alone treatment and/or an adjunct to surgical hair restoration. In addition, his new method of preparing PRP eliminates all unwanted cellular fragments that upon degradation can lead to oxidative injury to surrounding cells.
Dr. Cole has developed a new method of preparing PRP for his patients. The process involves lysing the platelets to release growth factors. Most clinics either do not activate the platelets or they activate with calcium gluconate. When clinics do not activate the PRP, there is very little release of growth factors, so the results are usually absent. When calcium gluconate is used with the PRP, there is a release of growth factors, but it is less than that when thrombin is used. Unfortunately, bovine thrombin caries many risks such as an allergic reaction and infections. Dr. Cole’s technique caries no risk like those of thrombin and the concentration of growth factors is often 6 to 8 times higher than the concentration from bovine thrombin. What Dr. Cole has noted is that the percentage of hairs remaining in the active growing phase following hair transplantation is much higher when he uses his revolutionary method of lysing platelets to release the growth factors. Dr. Cole was the first in the world to combine Acell with PRP, and this new method of preparing PRP once again sets a new industry standard for the use of PRP as both a stand alone treatment and/or an adjunct to surgical hair restoration. In addition, his new method of preparing PRP eliminates all unwanted cellular fragments that upon degradation can lead to oxidative injury to surrounding cells.