Desmond -- Update us on your topical fin experiment?

[maddy17]

Thank you for your informative posts. I love your photo (I am female but the guys board is way more active and honestly, you guys know more about this stuff.) The Espumil looks very interesting as a solution, read some of your other posts on fin. Their website does says Azaelic acid is "untested" with the Espumil, so you think it is compatible? I have taken the Blackseed Oil orally to decrease mast cell activation. also, Sodium Butyrate can also be taken orally, and when we have a really healthy gut and intake enough fiber our microbes make it, but if our diet is not perfect, if we have had antibiotic exposure, etc it can be depleted. Scientifically, it does many things, but it increases Tregs both in the gut and peripherally in tissue and Tregs downregulate mast cells. Mast cells are involved in hair loss. It also decreases the secretion of IL6 from the lining of intestines, and IL6 is an inflammatory cytokine with many downstream impacts. IL6 upregulates the adrenals response to ACTH, which means not only more cortisol but also more DHEA...which the body converts into androgens...source of DHT. S.B, also increases insulin sensitivity by 30%. Insulin makes the 5AR enzyme run faster, so we want lower insulin. It also upregulates adiponectin.