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  1. #1
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    Default Desmond -- Update us on your topical fin experiment?

    I know you explained how to create a topical finasteride almost a year ago and began using that, and you mentioned early on that you believed it was working due to it stopping the itching.

    In light of Hasson & Wong finally making their version available, are you still using topical finasteride? What have the results been? Any side effects? And were you using oral finasteride before that?

  2. #2
    Senior Member Desmond84's Avatar
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    Default

    Hi brother I've been meaning to update everyone here on topical finasteride but never got the chance to. So here it goes:

    We have been compounding topical finasteride for over a year now for a lot patients. Over this time, I've done a lot of research, so here's all you need to know. Making topical fin, CB, Minox or even RU is so easy you would not believe! All you need is:
    1. Your active ingredient
    2. Suitable solvent
    3. Espumil foaming solution

    Here's the link to Espumil:
    https://www.fagron.com/en/product-innovations/espumiltm

    That's all. For example to make topical fin:
    Crush your Finasteride tablets
    Dissolve in alcohol (solvent)
    Filter using a filter paper
    Add to Espumil solution
    Poor into a foaming bottle.
    Voila

    Thats it. It works and at least 20 ppl that I personally know of are using it.

    Here's a video to help you do it:



    Hope that helps everyone if you have questions about calculations, how much to put in, etc let me know and I'll post a thorough step by step protocol.

    Cheers,

    Des

  3. #3
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    Default

    where are the after photos of this guy?

  4. #4
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    Default

    Quote Originally Posted by Desmond84 View Post

    Thats it. It works and at least 20 ppl that I personally know of are using it.

    works the same as ingesting it?

  5. #5
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    Default

    Sides?

  6. #6
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    Default

    Hey Desmond ! About CB, Versapro and HRT cream is to forget ??? Espumil is a better vehicle ?? Thanks

  7. #7
    Senior Member Arashi's Avatar
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    Default

    What's the advantage here ? That you'd need to use less fin ?

  8. #8
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    Default

    does anyone know the topical ml you need to apply to inhibit a percent of serum DHT? Does it go systemic less then oral? I guess I also wonder what is the benefit to doing this work and going topical over internal?

  9. #9
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    Default

    Great, Desmond, you're here. Thanks much for the instructions. A few specific questions for you...

    1. You said 20 people are using it and it works. Do you mean 20 people who had side effects on oral finasteride are using topical finasteride effectively but WITHOUT side effects? Avoiding side effects of the pill is really what we're interested in here.

    2. Do you believe H&W's liposomal version makes sense, and is likely to make a difference compared to other formulations? (Particularly with regard to avoiding side effects?)


    Also, this is the 2007 paper on liposomal topical finasteride that someone cited: http://www.ncbi.nlm.nih.gov/pubmed/18161632

    The full paper -- which I can't make heads or tails of -- is here: https://www.scribd.com/doc/307372835...al-finasteride

    Maybe someone can interpret that for us.

  10. #10
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    Default Fin solution compounding

    Des is right on but let me add a couple of things:
    1. Finasteride is fully soluble in isopropyl alchohol 70%
    2. A lot of alc is not necessary. I dissolved 500mg in 20ml.
    3. Although readily soluble I let the fin and alc set for 30 minutes to assure solubility.
    4. Filter thru a funnel you can buy on line or perhaps kitchen section of home store.
    5. Pharmaceutical filters are usually less porous so I use 2 coffee cone filters that trap most of the fillers in the crushed fin in alc solution.
    6. Once you have the filtered product add Espumil to desired concentration.
    7. You don't have heat or stir vigorously like in the minoxidil demo.
    8. To calculate your desired strength remember per cent is calculated as number of grams of material per 100ml. So a 5% solution would have 5 grams in 100mls, 1% is one gram in 100ml. You can do your math to calculate the concentration you want which apparently according to Des gets results at various concentrations.

    And your local pharmacy or compounding pharmacy may be gracious enough to order Espumil for you.



    Quote Originally Posted by Desmond84 View Post
    Hi brother I've been meaning to update everyone here on topical finasteride but never got the chance to. So here it goes:

    We have been compounding topical finasteride for over a year now for a lot patients. Over this time, I've done a lot of research, so here's all you need to know. Making topical fin, CB, Minox or even RU is so easy you would not believe! All you need is:
    1. Your active ingredient
    2. Suitable solvent
    3. Espumil foaming solution

    Here's the link to Espumil:
    https://www.fagron.com/en/product-innovations/espumiltm

    That's all. For example to make topical fin:
    Crush your Finasteride tablets
    Dissolve in alcohol (solvent)
    Filter using a filter paper
    Add to Espumil solution
    Poor into a foaming bottle.
    Voila

    Thats it. It works and at least 20 ppl that I personally know of are using it.

    Here's a video to help you do it:



    Hope that helps everyone if you have questions about calculations, how much to put in, etc let me know and I'll post a thorough step by step protocol.

    Cheers,

    Des

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