View Poll Results: Niacin hurts or helps hair regrowth?
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Here is what I found, it's from 2012 on another hair loss forum. However, I have no idea if this info is correct. Maybe someone on here with better knowledge on the subject can confirm. I have a problem where I have bad circulation in my extremities (Raynaud's disease), so at the very least maybe Niacin can help that.
"There are two types of PGD2 receptors, DP1 and DP2 (DP2 is also known as 'GPR44' and 'CRTH2'). Laropiprant (Merck's drug) selectively blocks the PD1 receptor - Cotsarelis showed that the PD2 receptor (and not PD1) is involved in hair growth downregulation. BTW, niacin produces flushing via the PD1 receptor - the PD2 receptor is not involved in the flushing at all."
"Niacin flushes PGD2 through the receptor that have nothing to do with hair loss, Niacin flush doesn't make make you lose hair, in fact it makes PGD2 less available to be used with the receptor that damages the hair. And knowing that lowering PGD2 it more important that raising PGE and PGf2a, i would say Niacin is a must for anyone wanting to keep hair, based on all the information now available."
Last edited by Blushark; 02-15-2016 at 05:23 PM.
Reason: Bad referece
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