+ Reply to Thread
Page 1 of 9 1 2 3 ... LastLast
Results 1 to 10 of 89
  1. #1
    Junior Member
    Join Date
    May 2015
    Posts
    25

    Default New Topical Finasteride: Anchoring liposomes at the skin level (serum levels: 1/18th)

    Hi everyone,

    what do you think about this:
    https://hassonandwong.com/topical-fi...-prescription/
    https://3pfizs243h34c09mn6s0ul69-wpe...-DR-HASSON.pdf

    Here is a link to the website of the research group mentioned (Prof. Paola Minghetti):
    http://www.farmacia.unimi.it/Facolta..._ITA_HTML.html

    and, I think this might be the pharmacy offering this gel solution in Italy soon:
    http://www.farmaciaparati.it/

    The idea sounds great, though not sure how the silicon particles would cause the finasteride-loaded liposomes to physisorbe to the cells in the scalp. Maybe 'swooping', 'chemical', or someone else could comment on this.

    Thanks in advance

  2. #2
    Member
    Join Date
    Sep 2015
    Posts
    52

    Default

    I have 2 questions.

    1: If this is something that you use every day for the rest of your live, what happens to the silicone particles that you are introducing to your system. To my best knowledge silicone in not excreted from the body. Or is it sitting on top of your head and slowly releasing finasteride to your scalp? That would be good.

    2: Is that study all they did? If I understood it correctly they are basically guessing the systemic finasteride concentration based on an in vitro study and a mathematical formula?? They didn't even measure systemic finasteride concentrations by taking blood samples?

  3. #3
    Junior Member
    Join Date
    May 2015
    Posts
    25

    Default

    Quote Originally Posted by paleocapa89 View Post
    1: If this is something that you use every day for the rest of your live, what happens to the silicone particles that you are introducing to your system. To my best knowledge silicone in not excreted from the body. Or is it sitting on top of your head and slowly releasing finasteride to your scalp? That would be good.
    Silicon particles can be tuned to be biodegradable: http://www.nature.com/nmat/journal/v...f/nmat2398.pdf

  4. #4
    Member
    Join Date
    Sep 2015
    Posts
    52

    Default

    To my best understanding silicon and silicone are two different things. Although I am pretty sure the silicone in this case is sitting on top of the scalp and slowly releasing the finasteride, but some reassurance would be great.

  5. #5
    Member
    Join Date
    Apr 2015
    Posts
    47

    Default

    Quote Originally Posted by stratowich View Post
    Hi everyone,

    what do you think about this:
    https://hassonandwong.com/topical-fi...-prescription/
    https://3pfizs243h34c09mn6s0ul69-wpe...-DR-HASSON.pdf

    Here is a link to the website of the research group mentioned (Prof. Paola Minghetti):
    http://www.farmacia.unimi.it/Facolta..._ITA_HTML.html

    and, I think this might be the pharmacy offering this gel solution in Italy soon:
    http://www.farmaciaparati.it/

    The idea sounds great, though not sure how the silicon particles would cause the finasteride-loaded liposomes to physisorbe to the cells in the scalp. Maybe 'swooping', 'chemical', or someone else could comment on this.

    Thanks in advance
    A topical finasteride gel without side effects would be great.

    So when will this be available? And is it only in Italy?

  6. #6
    Junior Member
    Join Date
    Jan 2016
    Posts
    19

    Default

    Hope they will ship to Europe freely

  7. #7
    Junior Member
    Join Date
    Jan 2016
    Posts
    9

    Default

    If anyone is in Spain ISDIN have Finasteride with Minoxidil available.

  8. #8
    Member
    Join Date
    Aug 2014
    Posts
    61

    Default

    Doesn't this sound too simple and too good to be true? Not to mention somewhat out of the blue?

  9. #9
    Member
    Join Date
    Apr 2015
    Posts
    47

    Default

    They removed their blog post! WTF

  10. #10
    Junior Member
    Join Date
    May 2015
    Posts
    25

    Default

    Quote Originally Posted by paleocapa89 View Post
    To my best understanding silicon and silicone are two different things. Although I am pretty sure the silicone in this case is sitting on top of the scalp and slowly releasing the finasteride, but some reassurance would be great.
    Sorry mate, you are right, I was a bit to quick on that one. I thought they were manufacturing some kind of silicon nanoparticle liposome hybrid with special peptide targeting and internalization properties.

    I'm not really read up on silicones for skin products or drug-delivery so I can't provide deep educated comments on that. I will do some literature research on it in the next days/weeks and check back.

Similar Threads

  1. Skin expansion grows new skin and hair in burns victims
    By brunobald in forum Cutting Edge / Future Treatments
    Replies: 12
    Last Post: 02-27-2016, 05:43 PM
  2. Finasteride Oral x Finasteride Topical
    By theGirlfriend in forum Hair Loss Treatments
    Replies: 5
    Last Post: 02-10-2016, 09:15 PM
  3. ionic liquids facilitating deep skin penetration - helpful for topical dut/fin?
    By Difthin in forum Cutting Edge / Future Treatments
    Replies: 3
    Last Post: 09-15-2014, 10:10 PM
  4. Personal levels of tolerance and acceptance re finasteride sides
    By bobbyt in forum Men's Hair Loss: Start Your Own Topic
    Replies: 30
    Last Post: 07-15-2012, 03:43 PM
  5. Proscar EOD and DHT serum levels advice
    By diffusing in forum Introduce Yourself & Share Your Story
    Replies: 5
    Last Post: 02-26-2011, 03:53 PM

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts

» IAHRS

hair transplant surgeons

» The Bald Truth

» Recent Threads

Could I Pull Off The Bald Look?
03-22-2017 02:46 PM
by tomec1
Last Post By thome
Today 03:25 PM
Avodart / Finasteride shed
Yesterday 03:12 PM
Last Post By Spex
Today 01:47 PM
I may have jumped the gun
08-10-2017 09:29 PM
Last Post By Hairhope4ever
Today 01:23 PM
Sun Exposure after Hair Transplant
02-26-2009 02:36 PM
Last Post By Hairhope4ever
Today 01:20 PM
We're close!
Today 07:07 AM
by Jackito
Last Post By Hairhope4ever
Today 01:17 PM