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However, the effectiveness of Androgen Antagonists should be as follow: 1) pure 2) non pure and at the last 3) 5 alpha inhibitors. I sat down, and I thought what could be an alternative, and my eureka moment was when I was looking at the my stella beer. Yes! gene therapy seemed like an alternative alternative. I designed an Antisense Oligonucleotide, and blast the sequence to human genome, to make sure it specifically target AR with no off targets. Antisense Oligonucleotide are much cheaper to make than siRNA, so I chose them as my option. Also, once inside the cell, they can remain active for almost a week, Unlike siRNA's.
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