I'm going to be honest James. I think it's not going to do much. At least for AGA. Not better than minoxidil overall.
First of all the the pictures are extremely
unprofessional.
Some people focus on that one guy who had some regrowth. He did have regrowth, but the pictures differ that much and that makes it look way more impressive than it is. If we look at another picture for instance;
Like what the hell is that? I can't even comment on how sad it is if you have to showcase such a picture.
If you also compare the data of minoxidil to her data, minoxidil wins. I have seen better cosmetic regrowth from guys using minoxidil also than that "impressive" picture from Histogen too.
She also has zero reasoning to say that Histogen will work as a maintenance treatment, because it makes no sense. Like the guys from Replicel said basically; "Histogen just delivers factors that push the cells to work a little harder but doesn't do anything against the damage". I concur with that, because that is true. After all androgens will still be activating the AR.
The only thing I see good about Histogen is that it would be easier than something like minoxidil (getting a few injections with perhaps a better safety profile) instead of daily use. But I don't see it doing better than minoxidil as a whole. I see it being more effective for something like TE, and AFAIK she is planning a women only trial (smart, because women tend to suffer more from TE than men. See the picture of the lady with temple regrowth, that was TE).
Now comes the most funny part though;
https://www.zacksinvest.com/histogen-inc
She is lacking funding for a laughable amount of $18 million. That is pathetic. The hair transplant industry alone is soaring up to a $3 billion market annually. Add to that the sales of treatments like minoxidil, propecia and all the snake oil treatments.
We are talking about billions yearly here. There is much money to be made.
So ask yourself if Histogen would show a reasonable edge towards minoxidil or even challenge hair transplant then how the hell isn't it being funded? Perhaps more people see it as a joke?
A treatment that would challenge the hair transplant industry or be more effective than minoxidil by a reasonable margin would be worth a ton of cash, 18 million would be nothing. If you look at Allergan for instance, they have recently bought Kybella for hundreds of millions of dollars.
What do you think James?
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