inbeforethecure:
I do not know yet if Foxa2 is upregulated or downregulated in AGA individuals, not just necessarily in the scalp itself- but possibly in the organs that are vital to the scalp's functioning. (e.g thyroid, parathyroid, thymus- all of which Pax1 itself is heavily expressed in).
But what i do know from studies is that knockout of FOXa2 switches the response to TH2 cytokines- and this is the group of that is responsible for 'AGA itch' and is contained in sebocytes. So i will assume that FOXA2 is downregulated in AGA individuals. i might be wrong though.
I do not know yet if Foxa2 is upregulated or downregulated in AGA individuals, not just necessarily in the scalp itself- but possibly in the organs that are vital to the scalp's functioning. (e.g thyroid, parathyroid, thymus- all of which Pax1 itself is heavily expressed in).
But what i do know from studies is that knockout of FOXa2 switches the response to TH2 cytokines- and this is the group of that is responsible for 'AGA itch' and is contained in sebocytes. So i will assume that FOXA2 is downregulated in AGA individuals. i might be wrong though.
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