When is it appropriate to switch from finasteride to dutasteride?

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  • Centrino
    Junior Member
    • Jan 2015
    • 4

    When is it appropriate to switch from finasteride to dutasteride?

    Diffuse thinning - pronounced at crown.
    Been on finasteride (and Rogaine) for 2 years.
    Still slowly thinning. (Guessing the finasteride has slowed it, though.)
    But the hairloss has not actually been halted (or reversed).

    So I'm wondering if and when it's a good strategy to upgrade to dutasteride?

    Thanks.
  • allTheGoodNamesAreTaken
    Senior Member
    • Aug 2015
    • 342

    #2
    2 years is when I did it.

    Comment

    • Centrino
      Junior Member
      • Jan 2015
      • 4

      #3
      Originally posted by allTheGoodNamesAreTaken
      2 years is when I did it.
      How long ago was that? Why did you switch? Noticeable results due to the switch?

      Comment

      • allTheGoodNamesAreTaken
        Senior Member
        • Aug 2015
        • 342

        #4
        I carried on losing hair on finasteride (brand name propecia, not generic). I'd say it has carried on at roughly the same rate after I've switched to dutasteride (proper avodart) but it's hard to say. I'm 27, first noticed the very beginnings of a little bit of frontal recession at 21, started propecia at just before 23 once I could afford it. Switched to dutasteride at 25. Always purchased from pharmacydirectgb. I'm a thin NW2 now but the further back on the top of my head you go, the thicker it gets. My dad was fully bald on top by my age so this DHT reduction has probably slowed things down significantly, just hasn't stopped it. When I did switch I think I had a shed for a few months, there was definitely a period where I was losing more hair and I've been back to normal since then. I've never been a major shedder though. Oh, during most of the time I've been on dutasteride, I've also used Regenepure DR (the gentle shampoo with the ketoconazole in it), about 2-2.5 times a week roughly (leaving it on for a good ten minutes at least to soak in) and still slowly continued to lose hair. I stopped that a few months ago and have noticed no difference.

        Comment

        • rdawg
          Senior Member
          • Jun 2012
          • 1019

          #5
          Did it after two years as well, I've been on DUT for about 9 months now.

          it's a slow loss still, but the benefit is after the initial run-through of switching over, once it gets in your system you really only need to take it 1-2 times a week at most to keep it in your system.

          Fin would stay in my system for 2-3 days, DUT stays for about 21 days at the same level as day one.

          It's definitely stronger, but my hair is very slowly still going, can't imagine what it would be like without this stuff. Luckily we may have some new products within a few years so I can possibly get off this stuff once and for all because it definitely changes your system!

          Comment

          • Ziggyz123
            Senior Member
            • Feb 2015
            • 368

            #6
            Originally posted by Rashid Rashid, MD, PhD
            I think it is best to wait 1-2 years on finasteride and when the effects wear off and/or if it never had any effect then you can consider increasing the dose then moving on to duasteride. Overall, it should still be done under physician guidance.
            Hey Dr. Rashid,

            At one ear on finasteride I had a large shed, with burning pains/ bruised feeling on my hairline. Do ou think finasteride wore off and I should have switched to dutasteride?

            Comment

            • Frankthetank
              Junior Member
              • May 2015
              • 22

              #7
              I switched after 1 year on fin, been on dut for a little over 3 months now. I'm young and it wasn't stopping my loss so I figured i'd give it a shot before throwing in the towel

              as a side note, how is it possible for dut to not work for someone? it blocks out so much dht that it does not seem to make sense

              Comment

              • Frankthetank
                Junior Member
                • May 2015
                • 22

                #8
                Originally posted by rdawg
                it's a slow loss still, but the benefit is after the initial run-through of switching over, once it gets in your system you really only need to take it 1-2 times a week at most to keep it in your system.
                is this true? If i have been on dut for 3 months, does that mean that I can down my dose to a few times a week without loosing any efficacy? This would be a $ saver.

                Comment

                • hope777
                  Junior Member
                  • Jan 2015
                  • 16

                  #9
                  Originally posted by Frankthetank
                  how is it possible for dut to not work for someone? it blocks out so much dht that it does not seem to make sense
                  besides the how much of the dht they reduce (by blocking the 5aR enzyme), fin and dut work with different strength on different variants of the 5aR enzyme - hence some people with a certain variant may benefit more from fin while others may benefit more from dut.

                  see the study: http://www.ncbi.nlm.nih.gov/pubmed/15956333

                  Comment

                  • Dimoxynil
                    Senior Member
                    • Oct 2014
                    • 126

                    #10
                    Anyone got any positive stories to tell from switching ?

                    Comment

                    • Sanchez123
                      Member
                      • Jun 2016
                      • 67

                      #11
                      Originally posted by rdawg
                      Did it after two years as well, I've been on DUT for about 9 months now.

                      it's a slow loss still, but the benefit is after the initial run-through of switching over, once it gets in your system you really only need to take it 1-2 times a week at most to keep it in your system.

                      Fin would stay in my system for 2-3 days, DUT stays for about 21 days at the same level as day one.

                      It's definitely stronger, but my hair is very slowly still going, can't imagine what it would be like without this stuff. Luckily we may have some new products within a few years so I can possibly get off this stuff once and for all because it definitely changes your system!
                      rdawg, how is your hair now? Fin and dut do nothing for me.. so i am wondering if you are more lucky.

                      Comment

                      • osom
                        Junior Member
                        • May 2017
                        • 7

                        #12
                        did anyone see a leaflet mentioning the drug as an androgenetic balding treatment ?

                        Comment

                        • osom
                          Junior Member
                          • May 2017
                          • 7

                          #13
                          did anyone see a dutasteride drug mention on their leaflet that it promotes hair growth or is everyone just taking it as off-label. i mean is anyone living in south korea and did you see it ?

                          Comment

                          • Mehair
                            Junior Member
                            • Apr 2019
                            • 1

                            #14
                            I just skip the finasteride and go with dutasteride, it has worked wonders for me.

                            Comment

                            • Spex
                              Dr Representative
                              • Nov 2008
                              • 4289

                              #15
                              I found the switch of benefit. I was on fin 17 years on fin and switched onto Dut with positive results.

                              Regards
                              spex

                              A world renowned hair loss and hair transplant adviser. Spex has received several hair transplant procedures along with appropriate treatments!
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                              I am not a doctor or medical professional and my words should not be taken as medical advice. All opinions expressed are my own unless stated otherwise. Always consult with your own family doctor prior to embarking on any form of hair loss treatment or surgery.

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