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I remember when dr. Xu & dr. Cotsraelis converted ips cells to epithelial cells in 2014 many forum members said the final step was to make dermal papilla cells from ips cells. Fast forward to 2015, dr terskikh & sanford burnham researchers used ips cells to make dermal papilla. My question is using these 2 components can't they grow hair follicles in a dish and have a surgeon implant them one by one? This would be a full blown cure nw7 to nw1.
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I'm sure research and maybe even trials are going on in china that we don't know about. Chinese people are very secretive, don't like to disclose much info until they are 100%.
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Originally Posted by Renee
I remember when dr. Xu & dr. Cotsraelis converted ips cells to epithelial cells in 2014 many forum members said the final step was to make dermal papilla cells from ips cells. Fast forward to 2015, dr terskikh & sanford burnham researchers used ips cells to make dermal papilla. My question is using these 2 components can't they grow hair follicles in a dish and have a surgeon implant them one by one? This would be a full blown cure nw7 to nw1.
you're right. what the sanford-burham guys achieved is huge so far. the only setback is, that they mentioned, the iPS conversion to DP cells is not yet very efficient. something like 2 or 3% of the iPS cells are successfully converted and rest of it is trash. so in theory, with those 2 or 3% they could already make a proof of concept in human scalps, and i guess this is what they are planning within the next 2 years, especially now after they received a huge funding. so the low efficiency would mean they have to produce much more iPS cells (which is no problem) but i think low efficiency means more work and more culturing time in the lab and therefore much higher cost, for now.
if they find a way to get some automation into the game then even the low efficiency doesn't have to be a show-stopper. but of course they are probably going to try increase the efficiency first before they inject that stuff into human scalps.
it would really make sense for them to just do the proof of concept with some volunteers, to see if those from iPS created DP cells, which grew lot of hairs in mice with human grafted skin, also work in real scalps. after that they could concentrate on efficiency issues.
however, i think the sanford-burham research is the most promising so far. lauster and jahoda won't show any more progress, i think. they don't have a focus on curing hairloss. jahoda is just tinkering around in his lab and tries some funny experiments with DP cells, and lauster's team has its focus more on lab-on-a-chip technology (to replace cosmetic tests on animals). hair culturing or even a full hairloss cure has no priority for them. i don't expect anything from them anymore. even if dr. beren atac attends the congress in miami, it will be no revolutionizing news. she will just show some fancy powerpoint slides again, and mention that they have a lot more work to do.
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Dr terskikh said the next step is to test it in humans. Let's see.
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Originally Posted by lacazette
the first center was funded in 2000 by two Beijing universities and the Beijing Unit Wealth Company. After 8 years of collaboration the center launched several state level projects and gained support from national government. Based on the research results, they use stem cells for clinical treatment
http://www.chinastemcell.com.cn/en/A...013122974.html
We don't talk here about a crazy anonymous doctor or whatever
And 99% of their patients comes from all over the world, so you're out of the subject when you said "everything else is very poor and a lot of population is illiterate,.."
China have 1,35 billion population, so of course they will have a lot of good universities and very educated people, but on whole country level they are still very behind from Japan, Korea or Singapore.
Scientists claims everything, but they still didnt give us a good proof that stem cells will give significant results in humans. Stem cells therapies are still science fiction.
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Foofighter those patients exist, it's not what I call science fiction.
just one of their many exemples:
By Dr. Xu, Wang and Wu
Patient is a 56 year old male and UK citizen;
Admission Diagnosis: 1. Chronic Renal Failure (CRF)
2. Hypertension (3 degrees, extreme high risk)
Treatment Plan: The treatment program is 5 weeks
1. Active treatment for his primary affliction, control his blood pressure, prevent any complications.
2. Improve the patient internal environment; activate his own stem cells, prepare the stem cells for implantation.
3. Four times Mesenchymal Stem Cells (MSCs) implantation, comprehensive medication to help the survival of these stem cells.
4. Treatment to help the stem cells express normal functions in the patient body.
Treatment Results:
The edema has disappeared, the patient anemia improved very much: Hb increased to120g/L. Patient renal functioning had obvious improvement: BUN 7.2 mmol/L Cr 92 umol/L
We followed the patient for more than one year up to now, currently his condition is stable.
So yes we are at the beginning, but it's not science fiction.
Another study from national research in china regarding hair and Mesenchymal Stem Cells
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973717/
they used modified MSCs to repair hair follicle abnormalities and improved hair formation through HF structure remodeling
So it's good to see that for exemple this UK patient has been treated with MSCs treatment, and it's work, without side effects (for the moment)
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Originally Posted by lacazette
Foofighter those patients exist, it's not what I call science fiction.
just one of their many exemples:
By Dr. Xu, Wang and Wu
Patient is a 56 year old male and UK citizen;
Admission Diagnosis: 1. Chronic Renal Failure (CRF)
2. Hypertension (3 degrees, extreme high risk)
Treatment Plan: The treatment program is 5 weeks
1. Active treatment for his primary affliction, control his blood pressure, prevent any complications.
2. Improve the patient internal environment; activate his own stem cells, prepare the stem cells for implantation.
3. Four times Mesenchymal Stem Cells (MSCs) implantation, comprehensive medication to help the survival of these stem cells.
4. Treatment to help the stem cells express normal functions in the patient body.
Treatment Results:
The edema has disappeared, the patient anemia improved very much: Hb increased to120g/L. Patient renal functioning had obvious improvement: BUN 7.2 mmol/L Cr 92 umol/L
We followed the patient for more than one year up to now, currently his condition is stable.
So yes we are at the beginning, but it's not science fiction.
Another study from national research in china regarding hair and Mesenchymal Stem Cells
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973717/
they used modified MSCs to repair hair follicle abnormalities and improved hair formation through HF structure remodeling
So it's good to see that for exemple this UK patient has been treated with MSCs treatment, and it's work, without side effects (for the moment )
Maybe you know about marketing propaganda? Do you know that British men in real life, does he really exist or is just chinese imagination to cheat people and come to their clinics? Nigam also post pictures from his stem cell therapy as well
Don’t believe everything that you read on internet especeally this days when everyone have access to internet.
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Damn Foo, I can't do anything for you if you compare this as propaganda, nigam shit..
That was backed by national research in china, the universities,institutes,etc that funded the center are things like Wake forest, afirm, etc.. in usa if you want to compare.
Please before claiming taht everything in china is cheat, do your research and look on the National Natural Science Foundation of China, the National Research Program of China (call "973 program", look at their researchs on website), the National transgenic project, Institute of Genetics and Developmental Biology Chinese Academy of scienses, etc..and so on ..
You clearly have an old vision of china, it's 2015 dude they have the researchers and the technologies.
Sure they could have lonely scammers here and there that use the words "stem cells" for prp shit for a hair example, but it's mean nothing when it's come to national research
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Originally Posted by lacazette
Damn Foo, I can't do anything for you if you compare this as propaganda, nigam shit..
That was backed by national research in china, the universities,institutes,etc that funded the center are things like Wake forest, afirm, etc.. in usa if you want to compare.
Please before claiming taht everything in china is cheat, do your research and look on the National Natural Science Foundation of China, the National Research Program of China (call "973 program", look at their researchs on website), the National transgenic project, Institute of Genetics and Developmental Biology Chinese Academy of scienses, etc..and so on ..
You clearly have an old vision of china, it's 2015 dude they have the researchers and the technologies.
Sure they could have lonely scammers here and there that use the words "stem cells" for prp shit for a hair example, but it's mean nothing when it's come to national research
Actually in most stem cell therapies for hard diseases they give very poor or modest results. Why? We still dont know. Maybe stem cells are not that powerfull like we think.
http://www.newsmax.com/Health/Health.../30/id/659689/
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Just a quick heads up, http://stemcelltreatmentnow.com/about-us/ is currently working, but the website is rebranding, and is now at https://beikecelltherapy.com/about-beike-biotechnology/. Presently your link redirects, but this will likely end at some point soon. Would it be possible for you to update your link?
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